6GFR
cyanobacterial GAPDH with NAD
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006006 | biological_process | glucose metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006006 | biological_process | glucose metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050661 | molecular_function | NADP binding |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 36 |
| Details | binding site for residue NAD A 1001 |
| Chain | Residue |
| A | GLY8 |
| A | ALA99 |
| A | THR100 |
| A | GLY101 |
| A | THR123 |
| A | ALA124 |
| A | ASN317 |
| A | TYR321 |
| A | HOH1103 |
| A | HOH1121 |
| A | HOH1128 |
| A | PHE9 |
| A | HOH1137 |
| A | HOH1185 |
| A | HOH1187 |
| A | HOH1188 |
| A | HOH1203 |
| A | HOH1216 |
| A | HOH1220 |
| A | HOH1222 |
| A | HOH1226 |
| A | HOH1234 |
| A | GLY10 |
| A | HOH1237 |
| A | HOH1243 |
| A | HOH1251 |
| A | HOH1252 |
| A | HOH1253 |
| A | HOH1280 |
| B | HOH1157 |
| A | ARG11 |
| A | ILE12 |
| A | ASN35 |
| A | ASP36 |
| A | THR37 |
| A | ARG81 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue ACT A 1002 |
| Chain | Residue |
| A | SER153 |
| A | THR155 |
| A | THR212 |
| A | GLY213 |
| A | ARG235 |
| A | HOH1174 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1003 |
| Chain | Residue |
| A | GLY305 |
| A | ASN307 |
| A | HOH1184 |
| A | HOH1256 |
| A | HOH1260 |
| B | HOH1239 |
| site_id | AC4 |
| Number of Residues | 30 |
| Details | binding site for residue NAD B 1001 |
| Chain | Residue |
| A | HOH1163 |
| B | GLY8 |
| B | PHE9 |
| B | GLY10 |
| B | ARG11 |
| B | ILE12 |
| B | ASN35 |
| B | ASP36 |
| B | THR37 |
| B | ARG81 |
| B | ALA99 |
| B | THR100 |
| B | GLY101 |
| B | PHE103 |
| B | THR123 |
| B | ALA124 |
| B | ASN317 |
| B | TYR321 |
| B | ACT1003 |
| B | HOH1107 |
| B | HOH1113 |
| B | HOH1116 |
| B | HOH1122 |
| B | HOH1129 |
| B | HOH1134 |
| B | HOH1142 |
| B | HOH1151 |
| B | HOH1171 |
| B | HOH1177 |
| B | HOH1197 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 1002 |
| Chain | Residue |
| B | SER153 |
| B | THR155 |
| B | THR212 |
| B | GLY213 |
| B | HOH1112 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue ACT B 1003 |
| Chain | Residue |
| B | THR184 |
| B | ASP186 |
| B | NAD1001 |
Functional Information from PROSITE/UniProt
| site_id | PS00071 |
| Number of Residues | 8 |
| Details | GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL |
| Chain | Residue | Details |
| A | ALA152-LEU159 |
