6G9S

Structural basis for the inhibition of E. coli PBP2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004180	molecular_function	carboxypeptidase activity
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0008360	biological_process	regulation of cell shape
A	0008658	molecular_function	penicillin binding
A	0009002	molecular_function	serine-type D-Ala-D-Ala carboxypeptidase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0046677	biological_process	response to antibiotic
A	0071555	biological_process	cell wall organization
A	0071972	molecular_function	peptidoglycan L,D-transpeptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue ET5 A 701

Chain	Residue
A	ALA329
A	THR547
A	HOH818
A	HOH831
A	SER330
A	LYS333
A	TRP370
A	SER387
A	ASP389
A	ILE453
A	SER545
A	GLY546

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Acyl-ester intermediate => ECO:0000255|HAMAP-Rule:MF_02081, ECO:0000269|PubMed:3148617

Chain	Residue	Details
A	SER330

---