6G2D

Citrate-induced acetyl-CoA carboxylase (ACC-Cit) filament at 5.4 A resolution

GO（遺伝子オントロジー）由来の情報

鎖名	GO（遺伝子オントロジー）id	名前空間	内容
B	0000166	molecular_function	nucleotide binding
B	0001650	cellular_component	fibrillar center
B	0001894	biological_process	tissue homeostasis
B	0003824	molecular_function	catalytic activity
B	0003989	molecular_function	acetyl-CoA carboxylase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0006084	biological_process	acetyl-CoA metabolic process
B	0006629	biological_process	lipid metabolic process
B	0006631	biological_process	fatty acid metabolic process
B	0006633	biological_process	fatty acid biosynthetic process
B	0008152	biological_process	metabolic process
B	0008610	biological_process	lipid biosynthetic process
B	0015629	cellular_component	actin cytoskeleton
B	0016874	molecular_function	ligase activity
B	0019538	biological_process	protein metabolic process
B	0042802	molecular_function	identical protein binding
B	0044281	biological_process	small molecule metabolic process
B	0046872	molecular_function	metal ion binding
B	0046949	biological_process	fatty-acyl-CoA biosynthetic process
B	0051289	biological_process	protein homotetramerization
B	0055088	biological_process	lipid homeostasis
B	0071380	biological_process	cellular response to prostaglandin E stimulus
B	2001295	biological_process	malonyl-CoA biosynthetic process
C	0000166	molecular_function	nucleotide binding
C	0001650	cellular_component	fibrillar center
C	0001894	biological_process	tissue homeostasis
C	0003824	molecular_function	catalytic activity
C	0003989	molecular_function	acetyl-CoA carboxylase activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005829	cellular_component	cytosol
C	0006084	biological_process	acetyl-CoA metabolic process
C	0006629	biological_process	lipid metabolic process
C	0006631	biological_process	fatty acid metabolic process
C	0006633	biological_process	fatty acid biosynthetic process
C	0008152	biological_process	metabolic process
C	0008610	biological_process	lipid biosynthetic process
C	0015629	cellular_component	actin cytoskeleton
C	0016874	molecular_function	ligase activity
C	0019538	biological_process	protein metabolic process
C	0042802	molecular_function	identical protein binding
C	0044281	biological_process	small molecule metabolic process
C	0046872	molecular_function	metal ion binding
C	0046949	biological_process	fatty-acyl-CoA biosynthetic process
C	0051289	biological_process	protein homotetramerization
C	0055088	biological_process	lipid homeostasis
C	0071380	biological_process	cellular response to prostaglandin E stimulus
C	2001295	biological_process	malonyl-CoA biosynthetic process
D	0000166	molecular_function	nucleotide binding
D	0001650	cellular_component	fibrillar center
D	0001894	biological_process	tissue homeostasis
D	0003824	molecular_function	catalytic activity
D	0003989	molecular_function	acetyl-CoA carboxylase activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005829	cellular_component	cytosol
D	0006084	biological_process	acetyl-CoA metabolic process
D	0006629	biological_process	lipid metabolic process
D	0006631	biological_process	fatty acid metabolic process
D	0006633	biological_process	fatty acid biosynthetic process
D	0008152	biological_process	metabolic process
D	0008610	biological_process	lipid biosynthetic process
D	0015629	cellular_component	actin cytoskeleton
D	0016874	molecular_function	ligase activity
D	0019538	biological_process	protein metabolic process
D	0042802	molecular_function	identical protein binding
D	0044281	biological_process	small molecule metabolic process
D	0046872	molecular_function	metal ion binding
D	0046949	biological_process	fatty-acyl-CoA biosynthetic process
D	0051289	biological_process	protein homotetramerization
D	0055088	biological_process	lipid homeostasis
D	0071380	biological_process	cellular response to prostaglandin E stimulus
D	2001295	biological_process	malonyl-CoA biosynthetic process
F	0000166	molecular_function	nucleotide binding
F	0001650	cellular_component	fibrillar center
F	0001894	biological_process	tissue homeostasis
F	0003824	molecular_function	catalytic activity
F	0003989	molecular_function	acetyl-CoA carboxylase activity
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005829	cellular_component	cytosol
F	0006084	biological_process	acetyl-CoA metabolic process
F	0006629	biological_process	lipid metabolic process
F	0006631	biological_process	fatty acid metabolic process
F	0006633	biological_process	fatty acid biosynthetic process
F	0008152	biological_process	metabolic process
F	0008610	biological_process	lipid biosynthetic process
F	0015629	cellular_component	actin cytoskeleton
F	0016874	molecular_function	ligase activity
F	0019538	biological_process	protein metabolic process
F	0042802	molecular_function	identical protein binding
F	0044281	biological_process	small molecule metabolic process
F	0046872	molecular_function	metal ion binding
F	0046949	biological_process	fatty-acyl-CoA biosynthetic process
F	0051289	biological_process	protein homotetramerization
F	0055088	biological_process	lipid homeostasis
F	0071380	biological_process	cellular response to prostaglandin E stimulus
F	2001295	biological_process	malonyl-CoA biosynthetic process

UniProtにおけるモチーフ・データベースPROSITEからの機能情報

site_id	PS00188
残基数	18
詳細	BIOTIN Biotin-requiring enzymes attachment site. GQcYaeIeVMKMvmtLtA

鎖名	残基	詳細
B	GLY776-ALA793

---

site_id	PS00866
残基数	15
詳細	CPSASE_1 Carbamoyl-phosphate synthase subdomain signature 1. YPVMIKASeggGGkG

鎖名	残基	詳細
B	TYR306-GLY320

---

site_id	PS00867
残基数	8
詳細	CPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. FLELNPRL

鎖名	残基	詳細
B	PHE435-LEU442

---

SwissProt/UniProtに記載されている蛋白質分子機能情報

site_id	SWS_FT_FI1
残基数	4
詳細	ACT_SITE: ACT_SITE => ECO:0000250

鎖名	残基	詳細
B	ARG441
C	ARG441
D	ARG441
F	ARG441

---

site_id	SWS_FT_FI2
残基数	4
詳細	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00409

鎖名	残基	詳細
B	GLY315
C	GLY315
D	GLY315
F	GLY315

---

site_id	SWS_FT_FI3
残基数	12
詳細	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00409, ECO:0000255|PROSITE-ProRule:PRU00969

鎖名	残基	詳細
C	GLU437
C	ASN439
D	GLU424
D	GLU437
D	ASN439
F	GLU424
F	GLU437
F	ASN439
B	GLU424
B	GLU437
B	ASN439
C	GLU424

---

site_id	SWS_FT_FI4
残基数	12
詳細	BINDING: BINDING => ECO:0000250

鎖名	残基	詳細
D	ARG2129
F	ARG1823
F	LYS2127
F	ARG2129
B	ARG1823
B	LYS2127
B	ARG2129
C	ARG1823
C	LYS2127
C	ARG2129
D	ARG1823
D	LYS2127

---

site_id	SWS_FT_FI5
残基数	4
詳細	MOD_RES: N-acetylmethionine => ECO:0000269|Ref.9, ECO:0007744|PubMed:19369195, ECO:0007744|PubMed:20068231

鎖名	残基	詳細
B	MET1
C	MET1
D	MET1
F	MET1

---

site_id	SWS_FT_FI6
残基数	4
詳細	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19369195, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

鎖名	残基	詳細
B	SER5
C	SER5
D	SER5
F	SER5

---

site_id	SWS_FT_FI7
残基数	4
詳細	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231

鎖名	残基	詳細
D	SER23
F	SER23
B	SER23
C	SER23

---

site_id	SWS_FT_FI8
残基数	4
詳細	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

鎖名	残基	詳細
C	SER25
D	SER25
F	SER25
B	SER25

---

site_id	SWS_FT_FI9
残基数	4
詳細	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:19369195, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

鎖名	残基	詳細
C	SER29
D	SER29
B	SER29
F	SER29

---

site_id	SWS_FT_FI10
残基数	20
詳細	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P11497

鎖名	残基	詳細
B	SER1216
C	SER34
C	SER50
C	SER78
C	SER1201
C	SER1216
D	SER34
D	SER50
D	SER78
D	SER1201
D	SER1216
F	SER34
F	SER50
F	SER78
F	SER1201
F	SER1216
B	SER34
B	SER50
B	SER78
B	SER1201

---

site_id	SWS_FT_FI11
残基数	4
詳細	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231

鎖名	残基	詳細
B	SER48
C	SER48
D	SER48
F	SER48

---

site_id	SWS_FT_FI12
残基数	4
詳細	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983

鎖名	残基	詳細
B	SER53
C	SER53
D	SER53
F	SER53

---

site_id	SWS_FT_FI13
残基数	8
詳細	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q5SWU9

鎖名	残基	詳細
D	THR58
D	THR1227
F	THR58
F	THR1227
B	THR58
B	THR1227
C	THR58
C	THR1227

---

site_id	SWS_FT_FI14
残基数	4
詳細	MOD_RES: Phosphoserine => ECO:0000269|PubMed:29899443, ECO:0000269|Ref.9, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

鎖名	残基	詳細
B	SER80
C	SER80
D	SER80
F	SER80

---

site_id	SWS_FT_FI15
残基数	4
詳細	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18220336

鎖名	残基	詳細
B	SER488
C	SER488
D	SER488
F	SER488

---

site_id	SWS_FT_FI16
残基数	8
詳細	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163

鎖名	残基	詳細
D	THR610
D	THR2153
F	THR610
F	THR2153
B	THR610
B	THR2153
C	THR610
C	THR2153

---

site_id	SWS_FT_FI17
残基数	4
詳細	MOD_RES: N6-biotinyllysine => ECO:0000250|UniProtKB:P11497, ECO:0000255|PROSITE-ProRule:PRU01066

鎖名	残基	詳細
B	LYS786
C	LYS786
D	LYS786
F	LYS786

---

site_id	SWS_FT_FI18
残基数	4
詳細	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

鎖名	残基	詳細
B	SER835
C	SER835
D	SER835
F	SER835

---

site_id	SWS_FT_FI19
残基数	8
詳細	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q5SWU9

鎖名	残基	詳細
D	SER1218
D	SER1259
F	SER1218
F	SER1259
B	SER1218
B	SER1259
C	SER1218
C	SER1259

---

site_id	SWS_FT_FI20
残基数	4
詳細	MOD_RES: Phosphoserine => ECO:0000269|PubMed:16698035, ECO:0000269|PubMed:29899443

鎖名	残基	詳細
B	SER1263
C	SER1263
D	SER1263
F	SER1263

---

site_id	SWS_FT_FI21
残基数	4
詳細	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

鎖名	残基	詳細
B	SER1273
C	SER1273
D	SER1273
F	SER1273

---

site_id	SWS_FT_FI22
残基数	4
詳細	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

鎖名	残基	詳細
B	LYS1334
C	LYS1334
D	LYS1334
F	LYS1334

---