6FYX

Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C1)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000028	biological_process	ribosomal small subunit assembly
A	0002181	biological_process	cytoplasmic translation
A	0003735	molecular_function	structural constituent of ribosome
A	0005737	cellular_component	cytoplasm
A	0005840	cellular_component	ribosome
A	0006412	biological_process	translation
A	0015935	cellular_component	small ribosomal subunit
A	0022627	cellular_component	cytosolic small ribosomal subunit
A	0030686	cellular_component	90S preribosome
A	1990904	cellular_component	ribonucleoprotein complex
B	0003735	molecular_function	structural constituent of ribosome
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
B	0022627	cellular_component	cytosolic small ribosomal subunit
B	1990904	cellular_component	ribonucleoprotein complex
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
C	0015935	cellular_component	small ribosomal subunit
C	0022627	cellular_component	cytosolic small ribosomal subunit
C	1990904	cellular_component	ribonucleoprotein complex
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005634	cellular_component	nucleus
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0015935	cellular_component	small ribosomal subunit
D	0022626	cellular_component	cytosolic ribosome
D	0022627	cellular_component	cytosolic small ribosomal subunit
D	1990904	cellular_component	ribonucleoprotein complex
D	2001235	biological_process	positive regulation of apoptotic signaling pathway
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0019843	molecular_function	rRNA binding
E	0022627	cellular_component	cytosolic small ribosomal subunit
E	0032991	cellular_component	protein-containing complex
E	0043229	cellular_component	intracellular organelle
E	1990904	cellular_component	ribonucleoprotein complex
F	0000028	biological_process	ribosomal small subunit assembly
F	0003723	molecular_function	RNA binding
F	0003729	molecular_function	mRNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0015935	cellular_component	small ribosomal subunit
F	0019843	molecular_function	rRNA binding
F	0022627	cellular_component	cytosolic small ribosomal subunit
F	1990904	cellular_component	ribonucleoprotein complex
G	0003735	molecular_function	structural constituent of ribosome
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	1990904	cellular_component	ribonucleoprotein complex
H	0003735	molecular_function	structural constituent of ribosome
H	0005840	cellular_component	ribosome
H	0006364	biological_process	rRNA processing
H	0006412	biological_process	translation
H	0022627	cellular_component	cytosolic small ribosomal subunit
H	0030686	cellular_component	90S preribosome
H	0032040	cellular_component	small-subunit processome
H	0042274	biological_process	ribosomal small subunit biogenesis
H	1990904	cellular_component	ribonucleoprotein complex
I	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
I	0003735	molecular_function	structural constituent of ribosome
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0022627	cellular_component	cytosolic small ribosomal subunit
I	1990904	cellular_component	ribonucleoprotein complex
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0015935	cellular_component	small ribosomal subunit
J	0019843	molecular_function	rRNA binding
J	0022627	cellular_component	cytosolic small ribosomal subunit
J	0042274	biological_process	ribosomal small subunit biogenesis
J	0043226	cellular_component	organelle
J	1990904	cellular_component	ribonucleoprotein complex
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005737	cellular_component	cytoplasm
K	0022627	cellular_component	cytosolic small ribosomal subunit
L	0003735	molecular_function	structural constituent of ribosome
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0022627	cellular_component	cytosolic small ribosomal subunit
L	1990904	cellular_component	ribonucleoprotein complex
M	0003735	molecular_function	structural constituent of ribosome
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0022627	cellular_component	cytosolic small ribosomal subunit
M	1990904	cellular_component	ribonucleoprotein complex
N	0003735	molecular_function	structural constituent of ribosome
N	0005730	cellular_component	nucleolus
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0022627	cellular_component	cytosolic small ribosomal subunit
N	0070181	molecular_function	small ribosomal subunit rRNA binding
N	1990904	cellular_component	ribonucleoprotein complex
O	0000028	biological_process	ribosomal small subunit assembly
O	0003735	molecular_function	structural constituent of ribosome
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0022627	cellular_component	cytosolic small ribosomal subunit
O	1990904	cellular_component	ribonucleoprotein complex
P	0000028	biological_process	ribosomal small subunit assembly
P	0003723	molecular_function	RNA binding
P	0003735	molecular_function	structural constituent of ribosome
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0015935	cellular_component	small ribosomal subunit
P	0022627	cellular_component	cytosolic small ribosomal subunit
P	1990904	cellular_component	ribonucleoprotein complex
Q	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0022627	cellular_component	cytosolic small ribosomal subunit
Q	1990904	cellular_component	ribonucleoprotein complex
R	0003735	molecular_function	structural constituent of ribosome
R	0005829	cellular_component	cytosol
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	1990904	cellular_component	ribonucleoprotein complex
S	0003676	molecular_function	nucleic acid binding
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0015935	cellular_component	small ribosomal subunit
S	1990904	cellular_component	ribonucleoprotein complex
T	0000028	biological_process	ribosomal small subunit assembly
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0022627	cellular_component	cytosolic small ribosomal subunit
T	1990904	cellular_component	ribonucleoprotein complex
U	0003735	molecular_function	structural constituent of ribosome
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0015935	cellular_component	small ribosomal subunit
U	0022627	cellular_component	cytosolic small ribosomal subunit
U	1990904	cellular_component	ribonucleoprotein complex
V	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
V	0000461	biological_process	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
V	0003735	molecular_function	structural constituent of ribosome
V	0005737	cellular_component	cytoplasm
V	0005840	cellular_component	ribosome
V	0006364	biological_process	rRNA processing
V	0006412	biological_process	translation
V	0022627	cellular_component	cytosolic small ribosomal subunit
V	1990904	cellular_component	ribonucleoprotein complex
W	0003735	molecular_function	structural constituent of ribosome
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0022627	cellular_component	cytosolic small ribosomal subunit
W	1990904	cellular_component	ribonucleoprotein complex
X	0003735	molecular_function	structural constituent of ribosome
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0015935	cellular_component	small ribosomal subunit
X	0022627	cellular_component	cytosolic small ribosomal subunit
X	1990904	cellular_component	ribonucleoprotein complex
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005840	cellular_component	ribosome
Z	0022627	cellular_component	cytosolic small ribosomal subunit
Z	1990904	cellular_component	ribonucleoprotein complex
a	0003729	molecular_function	mRNA binding
a	0003735	molecular_function	structural constituent of ribosome
a	0005840	cellular_component	ribosome
a	0006412	biological_process	translation
a	0022627	cellular_component	cytosolic small ribosomal subunit
a	1990904	cellular_component	ribonucleoprotein complex
b	0000028	biological_process	ribosomal small subunit assembly
b	0003723	molecular_function	RNA binding
b	0003735	molecular_function	structural constituent of ribosome
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
b	0022627	cellular_component	cytosolic small ribosomal subunit
b	0046872	molecular_function	metal ion binding
b	1990904	cellular_component	ribonucleoprotein complex
c	0000028	biological_process	ribosomal small subunit assembly
c	0003735	molecular_function	structural constituent of ribosome
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
c	0022627	cellular_component	cytosolic small ribosomal subunit
c	0030490	biological_process	maturation of SSU-rRNA
c	1990904	cellular_component	ribonucleoprotein complex
d	0003735	molecular_function	structural constituent of ribosome
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
d	0008270	molecular_function	zinc ion binding
d	0022627	cellular_component	cytosolic small ribosomal subunit
d	1990904	cellular_component	ribonucleoprotein complex
e	0003735	molecular_function	structural constituent of ribosome
e	0005829	cellular_component	cytosol
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
e	0022627	cellular_component	cytosolic small ribosomal subunit
e	1990904	cellular_component	ribonucleoprotein complex
f	0003735	molecular_function	structural constituent of ribosome
f	0005634	cellular_component	nucleus
f	0005737	cellular_component	cytoplasm
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
f	0016567	biological_process	protein ubiquitination
f	0019941	biological_process	modification-dependent protein catabolic process
f	0031386	molecular_function	protein tag activity
f	0031625	molecular_function	ubiquitin protein ligase binding
f	0046872	molecular_function	metal ion binding
f	1990904	cellular_component	ribonucleoprotein complex
g	0001934	biological_process	positive regulation of protein phosphorylation
g	0005080	molecular_function	protein kinase C binding
g	0005634	cellular_component	nucleus
g	0005829	cellular_component	cytosol
g	0006417	biological_process	regulation of translation
g	0043022	molecular_function	ribosome binding
g	0045182	molecular_function	translation regulator activity
g	0072344	biological_process	rescue of stalled ribosome
h	0002181	biological_process	cytoplasmic translation
h	0003735	molecular_function	structural constituent of ribosome
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0005840	cellular_component	ribosome
h	0006412	biological_process	translation
h	0022625	cellular_component	cytosolic large ribosomal subunit
h	1990904	cellular_component	ribonucleoprotein complex
i	0001677	biological_process	formation of translation initiation ternary complex
i	0001731	biological_process	formation of translation preinitiation complex
i	0001732	biological_process	formation of cytoplasmic translation initiation complex
i	0002188	biological_process	translation reinitiation
i	0003723	molecular_function	RNA binding
i	0003725	molecular_function	double-stranded RNA binding
i	0003743	molecular_function	translation initiation factor activity
i	0005515	molecular_function	protein binding
i	0005737	cellular_component	cytoplasm
i	0006412	biological_process	translation
i	0006413	biological_process	translational initiation
i	0010494	cellular_component	cytoplasmic stress granule
i	0016282	cellular_component	eukaryotic 43S preinitiation complex
i	0019901	molecular_function	protein kinase binding
i	0031369	molecular_function	translation initiation factor binding
i	0033290	cellular_component	eukaryotic 48S preinitiation complex
i	0043024	molecular_function	ribosomal small subunit binding
j	0001731	biological_process	formation of translation preinitiation complex
j	0003676	molecular_function	nucleic acid binding
j	0003723	molecular_function	RNA binding
j	0003743	molecular_function	translation initiation factor activity
j	0005515	molecular_function	protein binding
j	0005525	molecular_function	GTP binding
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0005840	cellular_component	ribosome
j	0005850	cellular_component	eukaryotic translation initiation factor 2 complex
j	0006412	biological_process	translation
j	0006413	biological_process	translational initiation
j	0010494	cellular_component	cytoplasmic stress granule
j	0033290	cellular_component	eukaryotic 48S preinitiation complex
j	0043022	molecular_function	ribosome binding
j	0043614	cellular_component	multi-eIF complex
j	1990856	molecular_function	methionyl-initiator methionine tRNA binding
k	0000049	molecular_function	tRNA binding
k	0000166	molecular_function	nucleotide binding
k	0001731	biological_process	formation of translation preinitiation complex
k	0003743	molecular_function	translation initiation factor activity
k	0003924	molecular_function	GTPase activity
k	0005515	molecular_function	protein binding
k	0005525	molecular_function	GTP binding
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0005840	cellular_component	ribosome
k	0005850	cellular_component	eukaryotic translation initiation factor 2 complex
k	0006412	biological_process	translation
k	0006413	biological_process	translational initiation
k	0006417	biological_process	regulation of translation
k	0016259	biological_process	selenocysteine metabolic process
k	0016282	cellular_component	eukaryotic 43S preinitiation complex
k	0016787	molecular_function	hydrolase activity
k	0031369	molecular_function	translation initiation factor binding
k	0033290	cellular_component	eukaryotic 48S preinitiation complex
k	0035368	molecular_function	selenocysteine insertion sequence binding
k	0043614	cellular_component	multi-eIF complex
k	0045903	biological_process	positive regulation of translational fidelity
k	1990856	molecular_function	methionyl-initiator methionine tRNA binding
l	0001731	biological_process	formation of translation preinitiation complex
l	0001732	biological_process	formation of cytoplasmic translation initiation complex
l	0003729	molecular_function	mRNA binding
l	0003743	molecular_function	translation initiation factor activity
l	0005515	molecular_function	protein binding
l	0005525	molecular_function	GTP binding
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0005840	cellular_component	ribosome
l	0005850	cellular_component	eukaryotic translation initiation factor 2 complex
l	0006412	biological_process	translation
l	0006413	biological_process	translational initiation
l	0008270	molecular_function	zinc ion binding
l	0016282	cellular_component	eukaryotic 43S preinitiation complex
l	0031369	molecular_function	translation initiation factor binding
l	0043614	cellular_component	multi-eIF complex
l	0046872	molecular_function	metal ion binding
l	1990856	molecular_function	methionyl-initiator methionine tRNA binding
m	0000166	molecular_function	nucleotide binding
m	0001731	biological_process	formation of translation preinitiation complex
m	0001732	biological_process	formation of cytoplasmic translation initiation complex
m	0003743	molecular_function	translation initiation factor activity
m	0005092	molecular_function	GDP-dissociation inhibitor activity
m	0005096	molecular_function	GTPase activator activity
m	0005515	molecular_function	protein binding
m	0005525	molecular_function	GTP binding
m	0005829	cellular_component	cytosol
m	0006412	biological_process	translation
m	0006413	biological_process	translational initiation
m	0006446	biological_process	regulation of translational initiation
m	0008270	molecular_function	zinc ion binding
m	0031369	molecular_function	translation initiation factor binding
m	0033290	cellular_component	eukaryotic 48S preinitiation complex
m	0042256	biological_process	cytosolic ribosome assembly
m	0043614	cellular_component	multi-eIF complex
m	0045947	biological_process	negative regulation of translational initiation
m	0071074	molecular_function	eukaryotic initiation factor eIF2 binding
o	0000131	cellular_component	incipient cellular bud site
o	0001732	biological_process	formation of cytoplasmic translation initiation complex
o	0002183	biological_process	cytoplasmic translational initiation
o	0002188	biological_process	translation reinitiation
o	0003723	molecular_function	RNA binding
o	0003729	molecular_function	mRNA binding
o	0003743	molecular_function	translation initiation factor activity
o	0005515	molecular_function	protein binding
o	0005737	cellular_component	cytoplasm
o	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
o	0006412	biological_process	translation
o	0006413	biological_process	translational initiation
o	0010494	cellular_component	cytoplasmic stress granule
o	0016282	cellular_component	eukaryotic 43S preinitiation complex
o	0033290	cellular_component	eukaryotic 48S preinitiation complex
o	0043614	cellular_component	multi-eIF complex
o	0071540	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3e
o	0071541	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3m
p	0001732	biological_process	formation of cytoplasmic translation initiation complex
p	0002183	biological_process	cytoplasmic translational initiation
p	0003676	molecular_function	nucleic acid binding
p	0003723	molecular_function	RNA binding
p	0003743	molecular_function	translation initiation factor activity
p	0005515	molecular_function	protein binding
p	0005737	cellular_component	cytoplasm
p	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
p	0006412	biological_process	translation
p	0006413	biological_process	translational initiation
p	0010494	cellular_component	cytoplasmic stress granule
p	0016282	cellular_component	eukaryotic 43S preinitiation complex
p	0031369	molecular_function	translation initiation factor binding
p	0033290	cellular_component	eukaryotic 48S preinitiation complex
p	0042802	molecular_function	identical protein binding
p	0043614	cellular_component	multi-eIF complex
q	0003723	molecular_function	RNA binding
q	0003743	molecular_function	translation initiation factor activity
q	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
q	0006413	biological_process	translational initiation
q	0031369	molecular_function	translation initiation factor binding
r	0001732	biological_process	formation of cytoplasmic translation initiation complex
r	0002183	biological_process	cytoplasmic translational initiation
r	0003676	molecular_function	nucleic acid binding
r	0003723	molecular_function	RNA binding
r	0003743	molecular_function	translation initiation factor activity
r	0005737	cellular_component	cytoplasm
r	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
r	0006412	biological_process	translation
r	0006413	biological_process	translational initiation
r	0016282	cellular_component	eukaryotic 43S preinitiation complex
r	0033290	cellular_component	eukaryotic 48S preinitiation complex
s	0001732	biological_process	formation of cytoplasmic translation initiation complex
s	0002183	biological_process	cytoplasmic translational initiation
s	0002188	biological_process	translation reinitiation
s	0003723	molecular_function	RNA binding
s	0003743	molecular_function	translation initiation factor activity
s	0005515	molecular_function	protein binding
s	0005737	cellular_component	cytoplasm
s	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
s	0006412	biological_process	translation
s	0006413	biological_process	translational initiation
s	0010494	cellular_component	cytoplasmic stress granule
s	0016282	cellular_component	eukaryotic 43S preinitiation complex
s	0033290	cellular_component	eukaryotic 48S preinitiation complex
s	0043614	cellular_component	multi-eIF complex
s	0071541	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3m

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	binding site for residue MG 2 1801

Chain	Residue
2	G361

---

site_id	AC2
Number of Residues	2
Details	binding site for residue MG 2 1802

Chain	Residue
2	G95
2	G402

---

site_id	AC3
Number of Residues	3
Details	binding site for residue MG 2 1803

Chain	Residue
2	G551
2	A554
2	A555

---

site_id	AC4
Number of Residues	1
Details	binding site for residue MG 2 1804

Chain	Residue
2	A100

---

site_id	AC5
Number of Residues	1
Details	binding site for residue MG 2 1805

Chain	Residue
2	A1024

---

site_id	AC6
Number of Residues	2
Details	binding site for residue MG 2 1807

Chain	Residue
2	A424
2	C49

---

site_id	AC7
Number of Residues	2
Details	binding site for residue MG 2 1809

Chain	Residue
2	G1329
2	C1418

---

site_id	AC8
Number of Residues	1
Details	binding site for residue MG 2 1810

Chain	Residue
2	G10

---

site_id	AC9
Number of Residues	1
Details	binding site for residue MG 2 1811

Chain	Residue
2	A928

---

site_id	AD1
Number of Residues	4
Details	binding site for residue MG 2 1812

Chain	Residue
2	A1761
2	G1765
2	G1766
2	U1769

---

site_id	AD2
Number of Residues	1
Details	binding site for residue MG 2 1813

Chain	Residue
2	G547

---

site_id	AD3
Number of Residues	1
Details	binding site for residue MG 2 1814

Chain	Residue
2	A400

---

site_id	AD4
Number of Residues	1
Details	binding site for residue MG 2 1815

Chain	Residue
2	G16

---

site_id	AD5
Number of Residues	2
Details	binding site for residue MG 2 1816

Chain	Residue
2	A377
2	U378

---

site_id	AD6
Number of Residues	1
Details	binding site for residue MG 2 1817

Chain	Residue
2	A28

---

site_id	AD7
Number of Residues	3
Details	binding site for residue MG 2 1818

Chain	Residue
2	G370
2	A604
2	G606

---

site_id	AD8
Number of Residues	2
Details	binding site for residue MG 2 1819

Chain	Residue
2	G996
2	U1003

---

site_id	AD9
Number of Residues	1
Details	binding site for residue MG 2 1820

Chain	Residue
2	C426

---

site_id	AE1
Number of Residues	3
Details	binding site for residue MG 2 1821

Chain	Residue
2	A43
2	U44
2	A47

---

site_id	AE2
Number of Residues	4
Details	binding site for residue MG 2 1822

Chain	Residue
2	U1759
2	A1760
2	A1761
2	G1766

---

site_id	AE3
Number of Residues	3
Details	binding site for residue MG 2 1823

Chain	Residue
2	A618
2	A619
2	A620

---

site_id	AE4
Number of Residues	1
Details	binding site for residue MG 2 1824

Chain	Residue
2	G561

---

site_id	AE5
Number of Residues	1
Details	binding site for residue MG 2 1825

Chain	Residue
2	A618

---

site_id	AE6
Number of Residues	2
Details	binding site for residue MG 2 1826

Chain	Residue
2	G1327
2	G1329

---

site_id	AE7
Number of Residues	1
Details	binding site for residue MG 2 1827

Chain	Residue
2	A622

---

site_id	AE8
Number of Residues	4
Details	binding site for residue MG 2 1828

Chain	Residue
2	A100
2	U101
2	U102
2	C360

---

site_id	AE9
Number of Residues	1
Details	binding site for residue MG 2 1829

Chain	Residue
2	G20

---

site_id	AF1
Number of Residues	2
Details	binding site for residue MG 2 1830

Chain	Residue
2	G1111
2	A1112

---

site_id	AF2
Number of Residues	1
Details	binding site for residue MG 2 1831

Chain	Residue
2	U1768

---

site_id	AF3
Number of Residues	1
Details	binding site for residue MG 2 1832

Chain	Residue
2	G95

---

site_id	AF4
Number of Residues	2
Details	binding site for residue MG 2 1833

Chain	Residue
2	G1724
2	G1725

---

site_id	AF5
Number of Residues	4
Details	binding site for residue MG 2 1834

Chain	Residue
2	G1627
2	U1628
2	G1791
2	A1792

---

site_id	AF6
Number of Residues	2
Details	binding site for residue MG 2 1835

Chain	Residue
2	A62
2	U82

---

site_id	AF7
Number of Residues	1
Details	binding site for residue MG 2 1836

Chain	Residue
2	G1647

---

site_id	AF8
Number of Residues	2
Details	binding site for residue MG 2 1837

Chain	Residue
2	A459
2	G460

---

site_id	AF9
Number of Residues	1
Details	binding site for residue MG 2 1838

Chain	Residue
2	G466

---

site_id	AG1
Number of Residues	4
Details	binding site for residue MG 2 1839

Chain	Residue
2	A622
2	G623
2	C624
2	U1030

---

site_id	AG2
Number of Residues	2
Details	binding site for residue MG 2 1840

Chain	Residue
2	G984
2	G1013

---

site_id	AG3
Number of Residues	1
Details	binding site for residue MG 2 1843

Chain	Residue
2	U357

---

site_id	AG4
Number of Residues	2
Details	binding site for residue MG 2 1844

Chain	Residue
2	G1046
B	GLN157

---

site_id	AG5
Number of Residues	3
Details	binding site for residue MG 2 1846

Chain	Residue
2	G403
G	ARG88
G	GLU91

---

site_id	AG6
Number of Residues	1
Details	binding site for residue MG 2 1847

Chain	Residue
2	U1302

---

site_id	AG7
Number of Residues	2
Details	binding site for residue MG 2 1848

Chain	Residue
2	A978
2	U1014

---

site_id	AG8
Number of Residues	3
Details	binding site for residue MG 2 1849

Chain	Residue
2	U58
2	U88
2	G89

---

site_id	AG9
Number of Residues	2
Details	binding site for residue MG 2 1850

Chain	Residue
2	A760
2	G761

---

site_id	AH1
Number of Residues	3
Details	binding site for residue MG 2 1851

Chain	Residue
2	U8
2	A1138
2	G1139

---

site_id	AH2
Number of Residues	1
Details	binding site for residue MG 2 1852

Chain	Residue
2	C826

---

site_id	AH3
Number of Residues	2
Details	binding site for residue MG 2 1853

Chain	Residue
2	A514
2	C530

---

site_id	AH4
Number of Residues	1
Details	binding site for residue MG 2 1854

Chain	Residue
2	MG1855

---

site_id	AH5
Number of Residues	3
Details	binding site for residue MG 2 1855

Chain	Residue
2	G1293
2	G1294
2	MG1854

---

site_id	AH6
Number of Residues	1
Details	binding site for residue MG 2 1856

Chain	Residue
2	G937

---

site_id	AH7
Number of Residues	1
Details	binding site for residue MG 2 1857

Chain	Residue
2	U988

---

site_id	AH8
Number of Residues	2
Details	binding site for residue MG 2 1858

Chain	Residue
2	G213
2	A212

---

site_id	AH9
Number of Residues	4
Details	binding site for residue MG 2 1859

Chain	Residue
2	G1538
2	G1539
2	G1540
T	GLU44

---

site_id	AI1
Number of Residues	2
Details	binding site for residue MG 2 1863

Chain	Residue
2	G990
2	G1010

---

site_id	AI2
Number of Residues	4
Details	binding site for residue MG 2 1864

Chain	Residue
2	U1116
2	G1117
2	C1127
2	U1128

---

site_id	AI3
Number of Residues	2
Details	binding site for residue MG 2 1865

Chain	Residue
2	C1161
2	G1163

---

site_id	AI4
Number of Residues	1
Details	binding site for residue MG 2 1866

Chain	Residue
2	G924

---

site_id	AI5
Number of Residues	2
Details	binding site for residue MG 2 1868

Chain	Residue
2	C1158
2	U1282

---

site_id	AI6
Number of Residues	2
Details	binding site for residue MG 2 1869

Chain	Residue
2	A1467
2	G1539

---

site_id	AI7
Number of Residues	1
Details	binding site for residue MG 2 1871

Chain	Residue
2	C1455

---

site_id	AI8
Number of Residues	3
Details	binding site for residue MG 2 1872

Chain	Residue
2	G1199
2	G1200
2	A1598

---

site_id	AI9
Number of Residues	3
Details	binding site for residue MG 2 1874

Chain	Residue
2	A1195
2	C1196
2	C1463

---

site_id	AJ1
Number of Residues	4
Details	binding site for residue MG 2 1875

Chain	Residue
2	G1267
2	U1268
2	U1432
2	G1433

---

site_id	AJ2
Number of Residues	3
Details	binding site for residue MG 2 1876

Chain	Residue
2	G1272
2	C1273
2	2MG1426

---

site_id	AJ3
Number of Residues	3
Details	binding site for residue MG 2 1877

Chain	Residue
2	G1537
2	G1538
2	G1539

---

site_id	AJ4
Number of Residues	3
Details	binding site for residue MG 2 1878

Chain	Residue
2	A1481
2	G1482
2	U1520

---

site_id	AJ5
Number of Residues	4
Details	binding site for residue MG 2 1879

Chain	Residue
2	C1273
2	2MG1426
2	G1427
i	ARG13

---

site_id	AJ6
Number of Residues	3
Details	binding site for residue MG 2 1880

Chain	Residue
2	A1201
2	A1202
2	C1597

---

site_id	AJ7
Number of Residues	3
Details	binding site for residue MG 2 1882

Chain	Residue
2	A629
2	G630
2	C968

---

site_id	AJ8
Number of Residues	2
Details	binding site for residue MG 2 1883

Chain	Residue
2	U1184
2	C1455

---

site_id	AJ9
Number of Residues	4
Details	binding site for residue MG 2 1884

Chain	Residue
2	C1158
2	A1159
2	U1577
Q	TYR142

---

site_id	AK1
Number of Residues	2
Details	binding site for residue MG 2 1885

Chain	Residue
2	G1169
2	C1461

---

site_id	AK2
Number of Residues	2
Details	binding site for residue MG 2 1886

Chain	Residue
2	G1168
2	G1169

---

site_id	AK3
Number of Residues	2
Details	binding site for residue MG 2 1887

Chain	Residue
2	G1166
2	U1167

---

site_id	AK4
Number of Residues	2
Details	binding site for residue MG 2 1888

Chain	Residue
2	A1467
2	C1587

---

site_id	AK5
Number of Residues	4
Details	binding site for residue MG 2 1890

Chain	Residue
2	C1479
2	A1522
2	A1523
T	LEU79

---

site_id	AK6
Number of Residues	1
Details	binding site for residue MG 2 1891

Chain	Residue
2	U1767

---

site_id	AK7
Number of Residues	3
Details	binding site for residue MG 2 1892

Chain	Residue
2	G1766
2	U1767
3	A27

---

site_id	AK8
Number of Residues	2
Details	binding site for residue MG 2 1893

Chain	Residue
2	G1758
m	ASN30

---

site_id	AK9
Number of Residues	4
Details	binding site for residue MG 2 1897

Chain	Residue
2	U1793
2	A1795
a	GLY9
a	LYS34

---

site_id	AL1
Number of Residues	4
Details	binding site for residue MG 2 1898

Chain	Residue
2	C565
X	GLU60
X	ILE68
i	ARG62

---

site_id	AL2
Number of Residues	1
Details	binding site for residue MG 2 1899

Chain	Residue
2	A1631

---

site_id	AL3
Number of Residues	1
Details	binding site for residue MG 2 1900

Chain	Residue
2	C423

---

site_id	AL4
Number of Residues	4
Details	binding site for residue MG 2 1901

Chain	Residue
2	G91
2	G395
2	A396
2	G397

---

site_id	AL5
Number of Residues	2
Details	binding site for residue MG 2 1902

Chain	Residue
2	C249
2	A250

---

site_id	AL6
Number of Residues	1
Details	binding site for residue MG 2 1903

Chain	Residue
2	C401

---

site_id	AL7
Number of Residues	2
Details	binding site for residue MG 2 1904

Chain	Residue
2	A543
2	A544

---

site_id	AL8
Number of Residues	2
Details	binding site for residue MG 2 1905

Chain	Residue
2	A634
2	A635

---

site_id	AL9
Number of Residues	2
Details	binding site for residue MG 2 1906

Chain	Residue
2	A756
2	A792

---

site_id	AM1
Number of Residues	2
Details	binding site for residue MG 2 1907

Chain	Residue
2	A861
2	A862

---

site_id	AM2
Number of Residues	5
Details	binding site for residue MG 2 1908

Chain	Residue
2	G894
2	U895
2	G913
2	A914
2	U916

---

site_id	AM3
Number of Residues	2
Details	binding site for residue MG 2 1909

Chain	Residue
2	A969
2	A970

---

site_id	AM4
Number of Residues	2
Details	binding site for residue MG 2 1910

Chain	Residue
2	G1108
2	G1109

---

site_id	AM5
Number of Residues	1
Details	binding site for residue MG 2 1911

Chain	Residue
2	C1204

---

site_id	AM6
Number of Residues	4
Details	binding site for residue MG 2 1912

Chain	Residue
2	A1203
2	C1204
2	U1205
2	G1453

---

site_id	AM7
Number of Residues	2
Details	binding site for residue MG 2 1913

Chain	Residue
2	U1376
2	C1377

---

site_id	AM8
Number of Residues	2
Details	binding site for residue MG 2 1914

Chain	Residue
2	G1446
2	U1447

---

site_id	AM9
Number of Residues	2
Details	binding site for residue MG 2 1915

Chain	Residue
2	C1157
2	G1614

---

site_id	AN1
Number of Residues	2
Details	binding site for residue MG 2 1916

Chain	Residue
2	C1283
2	A1420

---

site_id	AN2
Number of Residues	4
Details	binding site for residue ZN a 500

Chain	Residue
a	CYS23
a	CYS26
a	CYS74
a	CYS77

---

site_id	AN3
Number of Residues	4
Details	binding site for residue ZN b 101

Chain	Residue
b	CYS56
b	CYS59
b	THR61
b	VAL62

---

site_id	AN4
Number of Residues	5
Details	binding site for residue ZN f 501

Chain	Residue
f	CYS121
f	CYS124
f	CYS139
f	LYS141
f	CYS142

---

site_id	AN5
Number of Residues	7
Details	binding site for residue MET k 601

Chain	Residue
1	A76
k	TYR142
k	ASN144
k	PHE381
k	ALA382
k	GLU383
k	LEU395

---

site_id	AN6
Number of Residues	3
Details	binding site for residue MG k 602

Chain	Residue
k	SER114
k	THR137
k	ASP193

---

site_id	AN7
Number of Residues	17
Details	binding site for residue GCP k 603

Chain	Residue
k	HIS108
k	VAL109
k	HIS111
k	GLY112
k	LYS113
k	SER114
k	THR115
k	ARG127
k	ASN135
k	ILE136
k	GLY196
k	ASN249
k	LYS250
k	ALA285
k	GLN286
l	THR238
l	SER264

---

site_id	AN8
Number of Residues	3
Details	binding site for residue ZN l 301

Chain	Residue
l	CYS236
l	THR238
l	SER264

---

site_id	AN9
Number of Residues	4
Details	binding site for residue ZN m 501

Chain	Residue
m	CYS99
m	CYS121
m	LYS126
m	THR128

---

site_id	AO1
Number of Residues	10
Details	binding site for residues 1MG 1 9 and 2MG 1 10

Chain	Residue
1	U8
1	C11
1	A21
1	G22
1	C23
1	C25
1	M2G26
1	U45
1	7MG46
1	H2U47

---

site_id	AO2
Number of Residues	5
Details	binding site for residues 7MG 1 46 and H2U 1 47

Chain	Residue
1	1MG9
1	A21
1	U45
1	5MC48
1	U50

---

site_id	AO3
Number of Residues	11
Details	binding site for residues H2U 1 47 and 5MC 1 48

Chain	Residue
1	G7
1	U8
1	1MG9
1	A14
1	G15
1	A21
1	G22
1	7MG46
1	5MC49
1	U50
1	A59

---

site_id	AO4
Number of Residues	13
Details	binding site for residues 5MC 1 48 and 5MC 1 49

Chain	Residue
1	G7
1	U8
1	A14
1	G15
1	A21
1	G22
1	7MG46
1	H2U47
1	U50
1	A59
1	RIA64
1	G65
1	C66

---

Functional Information from PROSITE/UniProt

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. AVSAswDkTLRLWNL

Chain	Residue	Details
g	ALA81-LEU95
g	ILE123-THR137
g	ALA218-LEU232
s	CYS67-VAL81

---

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KskIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
f	LYS27-ASP52

---

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVYKlglAkSvhhARvLI

Chain	Residue	Details
J	LEU105-ILE129

---

site_id	PS01191
Number of Residues	13
Details	RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVvEvCLaDL

Chain	Residue	Details
B	LEU61-LEU73

---

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. IAGGnDkqGfPM

Chain	Residue	Details
G	ILE52-MET63

---

site_id	PS00528
Number of Residues	15
Details	RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRLAaPhhWmLdK

Chain	Residue	Details
E	HIS8-LYS22

---

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvSQvyAirqAiAKGL

Chain	Residue	Details
Q	GLY71-LEU89

---

site_id	PS00712
Number of Residues	16
Details	RIBOSOMAL_S17E Ribosomal protein S17e signature. IqSKrLRNkIAGYtTH

Chain	Residue	Details
R	ILE41-HIS56

---

site_id	PS00996
Number of Residues	9
Details	RIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA

Chain	Residue	Details
V	LEU11-ALA19

---

site_id	PS00733
Number of Residues	8
Details	RIBOSOMAL_S26E Ribosomal protein S26e signature. YCISCAIH

Chain	Residue	Details
a	TYR73-HIS80

---

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. YGggKStGFGlVYNSvadakkfE

Chain	Residue	Details
Y	TYR64-GLU86

---

site_id	PS00548
Number of Residues	37
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfadGfLihSgqpVndfIEtatrhvlLrqGvlG

Chain	Residue	Details
D	ALA147-GLY183

---

site_id	PS01189
Number of Residues	19
Details	RIBOSOMAL_S12E Ribosomal protein S12e signature. ALKvvLrtSlvhDGLarGL

Chain	Residue	Details
M	ALA20-LEU38

---

site_id	PS01168
Number of Residues	33
Details	RIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgClnittvFShAqtavtCesCStvLctPtG

Chain	Residue	Details
b	LYS36-GLY68

---

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. AqLLLAARVHLG

Chain	Residue	Details
A	ALA14-GLY25

---

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlVIVtDprsDaqaIkEssyvNIP

Chain	Residue	Details
A	PRO118-PRO142

---

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
X	LYS62-ARG69

---

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY

Chain	Residue	Details
N	VAL98-TYR128

---

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
c	GLU58-LEU66

---

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGiRHfwGlrVRGQ

Chain	Residue	Details
S	ARG123-GLN136

---

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GLrIgrieDvTPvPSD

Chain	Residue	Details
O	LEU102-ASP124

---

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKvfnqveIrpemVGhyLGEFsiT

Chain	Residue	Details
P	ASN98-THR122

---

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsLMmngrnnGKKlkavrIVkhT

Chain	Residue	Details
F	GLU93-THR119

---

site_id	PS01193
Number of Residues	20
Details	RIBOSOMAL_S8E Ribosomal protein S8e signature. RaaTGAkraqf.RkKrKfELG

Chain	Residue	Details
I	ARG11-GLY30

---

site_id	PS01262
Number of Residues	23
Details	IF1A Eukaryotic initiation factor 1A signature. MlGnGRveasCfDGnkRmaHIrG

Chain	Residue	Details
i	MET41-GLY63

---

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GyvILTTSaGIMdheeAH

Chain	Residue	Details
W	GLY100-HIS117

---

site_id	PS00628
Number of Residues	20
Details	RIBOSOMAL_S19E Ribosomal protein S19e signature. PhkhvdaSgsInRkVLQsLE

Chain	Residue	Details
T	PRO90-GLU109

---

site_id	PS00948
Number of Residues	14
Details	RIBOSOMAL_S7E Ribosomal protein S7e signature. KLtRELEKKFQdRH

Chain	Residue	Details
H	LYS76-HIS89

---

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgQcRPIS

Chain	Residue	Details
L	GLY120-SER132

---

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAvvVVGDsn.GhVGlGiktak.EVag.AI

Chain	Residue	Details
C	GLY98-ILE130

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956

Chain	Residue	Details
s	SER302
k	ASN249
k	SER284

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q04067, ECO:0000255|HAMAP-Rule:MF_03006

Chain	Residue	Details
r	SER131
m	SER172
f	LYS27
f	LYS29
f	LYS33
f	LYS63

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956

Chain	Residue	Details
p	SER669
f	GLY76

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956

Chain	Residue	Details
m	SER228

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18407956

Chain	Residue	Details
m	THR317
l	SER118

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198

Chain	Residue	Details
m	SER397

---