6C3H
The crystal structure of 4-n-heptylbenzoate-bound CYP199A4
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006707 | biological_process | cholesterol catabolic process |
| A | 0008395 | molecular_function | steroid hydroxylase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0020037 | molecular_function | heme binding |
| A | 0036199 | molecular_function | cholest-4-en-3-one 26-monooxygenase activity |
| A | 0046872 | molecular_function | metal ion binding |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 20 |
| 詳細 | binding site for residue HEM A 501 |
| 鎖名 | 残基 |
| A | ILE97 |
| A | ARG300 |
| A | GLY350 |
| A | PHE351 |
| A | GLY352 |
| A | HIS356 |
| A | CYS358 |
| A | VAL359 |
| A | GLY360 |
| A | EJV502 |
| A | HOH708 |
| A | LEU98 |
| A | HOH714 |
| A | HIS105 |
| A | ARG109 |
| A | ALA248 |
| A | GLY249 |
| A | THR252 |
| A | THR253 |
| A | PHE298 |
| site_id | AC2 |
| 残基数 | 12 |
| 詳細 | binding site for residue EJV A 502 |
| 鎖名 | 残基 |
| A | VAL80 |
| A | ARG92 |
| A | SER95 |
| A | LEU98 |
| A | PHE182 |
| A | PHE185 |
| A | SER244 |
| A | ALA248 |
| A | PHE298 |
| A | THR395 |
| A | HEM501 |
| A | HOH664 |
| site_id | AC3 |
| 残基数 | 4 |
| 詳細 | binding site for residue CL A 503 |
| 鎖名 | 残基 |
| A | TYR177 |
| A | GLN203 |
| A | ASN207 |
| A | HOH942 |
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
| site_id | PS00086 |
| 残基数 | 10 |
| 詳細 | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGsGVHMCVG |
| 鎖名 | 残基 | 詳細 |
| A | PHE351-GLY360 |
