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6A1R

Mandelate oxidase mutant-Y128F with the N5-phenylacetyl-FMN adduct

Functional Information from GO Data
ChainGOidnamespacecontents
A0001561biological_processfatty acid alpha-oxidation
A0004459molecular_functionL-lactate dehydrogenase activity
A0005777cellular_componentperoxisome
A0005886cellular_componentplasma membrane
A0010181molecular_functionFMN binding
A0016491molecular_functionoxidoreductase activity
A0016899molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
A0017000biological_processantibiotic biosynthetic process
A0019516biological_processlactate oxidation
A0033072biological_processvancomycin biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues26
Detailsbinding site for residue 9OC A 401
ChainResidue
ALEU25
AMET160
APHE206
ALYS228
ASER250
AHIS252
AGLY253
AARG255
AASP283
AGLY284
AGLY285
AALA76
AARG287
AGLY306
AARG307
AMG402
AHOH563
AHOH603
AHOH605
APRO77
AVAL78
AALA79
ALEU108
AGLN126
APHE128
ATHR154

site_idAC2
Number of Residues5
Detailsbinding site for residue MG A 402
ChainResidue
AGLY284
AGLY285
AILE286
ALEU304
A9OC401

Functional Information from PROSITE/UniProt
site_idPS00557
Number of Residues7
DetailsFMN_HYDROXY_ACID_DH_1 FMN-dependent alpha-hydroxy acid dehydrogenases active site. SNHGGRQ
ChainResidueDetails
ASER250-GLN256

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00683
ChainResidueDetails
AHIS252

site_idSWS_FT_FI2
Number of Residues8
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00683
ChainResidueDetails
APHE128
ATHR154
AARG163
ALYS228
AARG255
AASP283
AGLY306
AGLN126

218500

건을2024-04-17부터공개중

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