5YXL
A ligand M binding to FXR
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0032052 | molecular_function | bile acid binding |
| A | 0038183 | biological_process | bile acid signaling pathway |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004879 | molecular_function | nuclear receptor activity |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0032052 | molecular_function | bile acid binding |
| C | 0038183 | biological_process | bile acid signaling pathway |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 13 |
| 詳細 | binding site for residue NIW A 301 |
| 鎖名 | 残基 |
| A | PHE41 |
| A | HIS204 |
| A | MET207 |
| A | VAL213 |
| A | TRP226 |
| A | THR45 |
| A | HIS51 |
| A | MET85 |
| A | PHE86 |
| A | SER89 |
| A | ILE114 |
| A | TYR118 |
| A | MET122 |
| site_id | AC2 |
| 残基数 | 15 |
| 詳細 | binding site for residue NIW C 301 |
| 鎖名 | 残基 |
| C | PHE41 |
| C | LEU44 |
| C | THR45 |
| C | ALA48 |
| C | HIS51 |
| C | MET85 |
| C | PHE86 |
| C | ILE114 |
| C | TYR118 |
| C | MET122 |
| C | PHE200 |
| C | HIS203 |
| C | HIS204 |
| C | MET207 |
| C | TRP226 |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 8 |
| 詳細 | BINDING: BINDING => ECO:0007744|PDB:6HL1 |
| 鎖名 | 残基 | 詳細 |
| A | ARG88 | |
| A | TYR118 | |
| A | TYR126 | |
| A | HIS204 | |
| C | ARG88 | |
| C | TYR118 | |
| C | TYR126 | |
| C | HIS204 |
| site_id | SWS_FT_FI2 |
| 残基数 | 2 |
| 詳細 | MOD_RES: Phosphothreonine; by PKC/PRKCZ => ECO:0000305|PubMed:18668687 |
| 鎖名 | 残基 | 詳細 |
| A | THR199 | |
| C | THR199 |
| site_id | SWS_FT_FI3 |
| 残基数 | 4 |
| 詳細 | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0000305|PubMed:23546875 |
| 鎖名 | 残基 | 詳細 |
| A | LYS32 | |
| C | LYS32 |
