5X9H
Crystal structure of the Mg2+ channel MgtE in complex with ATP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006812 | biological_process | monoatomic cation transport |
| A | 0008324 | molecular_function | monoatomic cation transmembrane transporter activity |
| A | 0015095 | molecular_function | magnesium ion transmembrane transporter activity |
| A | 0015693 | biological_process | magnesium ion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0098655 | biological_process | monoatomic cation transmembrane transport |
| A | 1903830 | biological_process | magnesium ion transmembrane transport |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006812 | biological_process | monoatomic cation transport |
| B | 0008324 | molecular_function | monoatomic cation transmembrane transporter activity |
| B | 0015095 | molecular_function | magnesium ion transmembrane transporter activity |
| B | 0015693 | biological_process | magnesium ion transport |
| B | 0016020 | cellular_component | membrane |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0098655 | biological_process | monoatomic cation transmembrane transport |
| B | 1903830 | biological_process | magnesium ion transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue ATP A 501 |
| Chain | Residue |
| A | TYR170 |
| A | PRO231 |
| B | GLU166 |
| B | TYR169 |
| A | VAL183 |
| A | SER185 |
| A | ARG187 |
| A | ASN203 |
| A | LYS205 |
| A | VAL206 |
| A | VAL207 |
| A | PHE227 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 502 |
| Chain | Residue |
| A | ASP432 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 504 |
| Chain | Residue |
| A | ASP259 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 505 |
| Chain | Residue |
| A | ASP91 |
| A | ASP247 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 506 |
| Chain | Residue |
| A | ALA223 |
| A | ASP226 |
| B | ASP250 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 507 |
| Chain | Residue |
| A | ASP95 |
| A | GLY136 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 508 |
| Chain | Residue |
| A | GLU59 |
| B | ASP226 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 509 |
| Chain | Residue |
| A | ASP226 |
| B | GLU59 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | binding site for residue ATP B 501 |
| Chain | Residue |
| A | GLU166 |
| A | TYR169 |
| B | TYR170 |
| B | VAL183 |
| B | SER185 |
| B | ARG187 |
| B | ASP188 |
| B | ASN203 |
| B | LYS205 |
| B | VAL206 |
| B | VAL207 |
| B | PHE227 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 502 |
| Chain | Residue |
| B | ALA223 |
| B | ASP224 |
| B | ASP226 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 504 |
| Chain | Residue |
| B | GLU216 |
| B | ASP259 |
| B | ASP418 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 505 |
| Chain | Residue |
| B | ASP91 |
| B | GLU166 |
| B | ASP247 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue MG B 506 |
| Chain | Residue |
| B | ASP95 |
| B | GLY136 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 610 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:17700703, ECO:0000269|PubMed:25367295 |
| Chain | Residue | Details |
| A | MET1-LEU283 | |
| A | ILE338-ASP351 | |
| A | PHE410-ALA420 | |
| B | MET1-LEU283 | |
| B | ILE338-ASP351 | |
| B | PHE410-ALA420 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 234 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:25367295, ECO:0007744|PDB:4U9L, ECO:0007744|PDB:4U9N, ECO:0007744|PDB:4WIB |
| Chain | Residue | Details |
| A | ALA284-PHE306 | |
| B | LEU421-ALA443 | |
| A | LEU316-LEU337 | |
| A | TRP352-ASP381 | |
| A | LEU386-PRO409 | |
| A | LEU421-ALA443 | |
| B | ALA284-PHE306 | |
| B | LEU316-LEU337 | |
| B | TRP352-ASP381 | |
| B | LEU386-PRO409 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 34 |
| Details | TOPO_DOM: Periplasmic => ECO:0000269|PubMed:17700703, ECO:0000269|PubMed:25367295 |
| Chain | Residue | Details |
| A | GLU307-ALA315 | |
| A | GLY382-LEU385 | |
| A | ARG444-VAL450 | |
| B | GLU307-ALA315 | |
| B | GLY382-LEU385 | |
| B | ARG444-VAL450 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19798051, ECO:0000269|PubMed:28747715 |
| Chain | Residue | Details |
| A | GLU59 | |
| B | ASP432 | |
| A | GLU216 | |
| A | GLU255 | |
| A | GLU258 | |
| A | ASP432 | |
| B | GLU59 | |
| B | GLU216 | |
| B | GLU255 | |
| B | GLU258 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19798051, ECO:0000269|PubMed:28747715, ECO:0007744|PDB:2ZY9, ECO:0007744|PDB:5X9G, ECO:0007744|PDB:5X9H |
| Chain | Residue | Details |
| A | ASP91 | |
| A | ASP95 | |
| A | GLY136 | |
| A | ASP247 | |
| B | ASP91 | |
| B | ASP95 | |
| B | GLY136 | |
| B | ASP247 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28747715, ECO:0007744|PDB:5X9G, ECO:0007744|PDB:5X9H |
| Chain | Residue | Details |
| A | TYR170 | |
| B | VAL207 | |
| A | SER185 | |
| A | ARG187 | |
| A | ASP188 | |
| A | VAL207 | |
| B | TYR170 | |
| B | SER185 | |
| B | ARG187 | |
| B | ASP188 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19798051, ECO:0000269|PubMed:28747715, ECO:0007744|PDB:2ZY9, ECO:0007744|PDB:5X9H |
| Chain | Residue | Details |
| A | ALA223 | |
| A | ASP226 | |
| A | ASP250 | |
| B | ALA223 | |
| B | ASP226 | |
| B | ASP250 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19798051, ECO:0000269|PubMed:28747715, ECO:0007744|PDB:2ZY9 |
| Chain | Residue | Details |
| A | ASP259 | |
| A | ASP418 | |
| B | ASP259 | |
| B | ASP418 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:25367295, ECO:0007744|PDB:4U9N |
| Chain | Residue | Details |
| A | GLU275 | |
| B | HIS383 | |
| A | GLN304 | |
| A | GLU307 | |
| A | GLU311 | |
| A | HIS383 | |
| B | GLU275 | |
| B | GLN304 | |
| B | GLU307 | |
| B | GLU311 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19798051 |
| Chain | Residue | Details |
| A | ALA428 | |
| B | ALA428 |
