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5IQP

14-3-3 PROTEIN TAU ISOFORM

GO(遺伝子オントロジー)由来の情報
鎖名GO(遺伝子オントロジー)id名前空間内容
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005925cellular_componentfocal adhesion
A0006605biological_processprotein targeting
A0007165biological_processsignal transduction
A0007264biological_processsmall GTPase-mediated signal transduction
A0016020cellular_componentmembrane
A0019904molecular_functionprotein domain specific binding
A0021762biological_processsubstantia nigra development
A0032991cellular_componentprotein-containing complex
A0034766biological_processnegative regulation of monoatomic ion transmembrane transport
A0042802molecular_functionidentical protein binding
A0044325molecular_functiontransmembrane transporter binding
A0045202cellular_componentsynapse
A0045892biological_processnegative regulation of DNA-templated transcription
A0070062cellular_componentextracellular exosome
A0071889molecular_function14-3-3 protein binding
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005925cellular_componentfocal adhesion
B0006605biological_processprotein targeting
B0007165biological_processsignal transduction
B0007264biological_processsmall GTPase-mediated signal transduction
B0016020cellular_componentmembrane
B0019904molecular_functionprotein domain specific binding
B0021762biological_processsubstantia nigra development
B0032991cellular_componentprotein-containing complex
B0034766biological_processnegative regulation of monoatomic ion transmembrane transport
B0042802molecular_functionidentical protein binding
B0044325molecular_functiontransmembrane transporter binding
B0045202cellular_componentsynapse
B0045892biological_processnegative regulation of DNA-templated transcription
B0070062cellular_componentextracellular exosome
B0071889molecular_function14-3-3 protein binding
PDBデータベースに由来する情報
site_idAC1
残基数4
詳細binding site for residue SO4 A 301
鎖名残基
ALYS49
AARG56
AARG127
ATYR128

site_idAC2
残基数5
詳細binding site for residue SO4 B 601
鎖名残基
BARG56
BARG127
BTYR128
BHOH715
BHOH747

UniProtにおけるモチーフ・データベースPROSITEからの機能情報
site_idPS00796
残基数11
詳細1433_1 14-3-3 proteins signature 1. RNLLSVAYKNV
鎖名残基詳細
AARG41-VAL51

site_idPS00797
残基数20
詳細1433_2 14-3-3 proteins signature 2. YKDSTLIMQLLRDNLTLWTS
鎖名残基詳細
ATYR211-SER230

SwissProt/UniProtに記載されている蛋白質分子機能情報
site_idSWS_FT_FI1
残基数4
詳細SITE: Interaction with phosphoserine on interacting protein
鎖名残基詳細
AARG56
AARG127
BARG56
BARG127

site_idSWS_FT_FI2
残基数2
詳細MOD_RES: N-acetylmethionine => ECO:0000269|Ref.8, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712
鎖名残基詳細
AMET1
BMET1

site_idSWS_FT_FI3
残基数6
詳細MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
鎖名残基詳細
ALYS3
ALYS68
ALYS115
BLYS3
BLYS68
BLYS115

site_idSWS_FT_FI4
残基数2
詳細MOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861
鎖名残基詳細
ALYS49
BLYS49

site_idSWS_FT_FI5
残基数4
詳細MOD_RES: 3'-nitrotyrosine => ECO:0000250|UniProtKB:Q9CQV8
鎖名残基詳細
ATYR82
ATYR104
BTYR82
BTYR104

site_idSWS_FT_FI6
残基数2
詳細MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P68254
鎖名残基詳細
ASER92
BSER92

site_idSWS_FT_FI7
残基数2
詳細MOD_RES: Phosphoserine => ECO:0000269|PubMed:9360956, ECO:0007744|PubMed:18669648
鎖名残基詳細
ASER232
BSER232

site_idSWS_FT_FI8
残基数4
詳細CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733
鎖名残基詳細
ALYS49
BLYS49

218853

件を2024-04-24に公開中

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