5HSI
Crystal structure of tyrosine decarboxylase at 1.73 Angstroms resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004058 | molecular_function | aromatic-L-amino-acid decarboxylase activity |
| A | 0004837 | molecular_function | tyrosine decarboxylase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016830 | molecular_function | carbon-carbon lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0036468 | molecular_function | L-dopa decarboxylase activity |
| B | 0004058 | molecular_function | aromatic-L-amino-acid decarboxylase activity |
| B | 0004837 | molecular_function | tyrosine decarboxylase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016830 | molecular_function | carbon-carbon lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0019752 | biological_process | carboxylic acid metabolic process |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0036468 | molecular_function | L-dopa decarboxylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 701 |
| Chain | Residue |
| A | HOH822 |
| A | HOH946 |
| A | HOH1128 |
| B | HOH829 |
| B | HOH1148 |
| B | HOH1387 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000305|PubMed:27292129 |
| Chain | Residue | Details |
| A | TYR420 | |
| B | TYR420 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: in other chain => ECO:0000269|PubMed:27292129 |
| Chain | Residue | Details |
| A | ASP389 | |
| B | GLY158 | |
| B | THR298 | |
| B | ASP389 | |
| A | GLY158 | |
| A | THR298 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27292129 |
| Chain | Residue | Details |
| A | SER440 | |
| B | SER440 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000269|PubMed:27292129, ECO:0007744|PDB:5HSJ |
| Chain | Residue | Details |
| A | LYS392 | |
| B | LYS392 |
