5F3W

Structure of the ATPrS-Mre11/Rad50-DNA complex

GO（遺伝子オントロジー）由来の情報

鎖名	GO（遺伝子オントロジー）id	名前空間	内容
A	0000403	molecular_function	Y-form DNA binding
A	0003677	molecular_function	DNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004527	molecular_function	exonuclease activity
A	0004529	molecular_function	DNA exonuclease activity
A	0006281	biological_process	DNA repair
A	0006302	biological_process	double-strand break repair
A	0006974	biological_process	DNA damage response
A	0008408	molecular_function	3'-5' exonuclease activity
A	0016787	molecular_function	hydrolase activity
A	0030145	molecular_function	manganese ion binding
A	0042802	molecular_function	identical protein binding
A	0045027	molecular_function	DNA end binding
A	0046872	molecular_function	metal ion binding
B	0006302	biological_process	double-strand break repair
B	0016887	molecular_function	ATP hydrolysis activity
C	0000403	molecular_function	Y-form DNA binding
C	0003677	molecular_function	DNA binding
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0004527	molecular_function	exonuclease activity
C	0004529	molecular_function	DNA exonuclease activity
C	0006281	biological_process	DNA repair
C	0006302	biological_process	double-strand break repair
C	0006974	biological_process	DNA damage response
C	0008408	molecular_function	3'-5' exonuclease activity
C	0016787	molecular_function	hydrolase activity
C	0030145	molecular_function	manganese ion binding
C	0042802	molecular_function	identical protein binding
C	0045027	molecular_function	DNA end binding
C	0046872	molecular_function	metal ion binding
D	0006302	biological_process	double-strand break repair
D	0016887	molecular_function	ATP hydrolysis activity

PDBデータベースに由来する情報

site_id	AC1
残基数	5
詳細	binding site for residue MG A 401

鎖名	残基
A	ASP8
A	HIS10
A	ASP49
A	HIS188
A	MG402

---

site_id	AC2
残基数	5
詳細	binding site for residue MG A 402

鎖名	残基
A	MG401
A	ASP49
A	ASN84
A	HIS158
A	HIS186

---

site_id	AC3
残基数	22
詳細	binding site for residue AGS B 1101

鎖名	残基
B	LYS14
B	SER15
B	GLY35
B	SER36
B	GLY37
B	LYS38
B	SER39
B	SER40
B	THR60
B	ILE62
B	THR63
B	LYS64
B	GLN134
B	ASP946
B	GLU947
B	LYS994
D	TYR890
D	LEU910
D	ASN914
D	SER916
D	GLY917
D	GLU919

---

site_id	AC4
残基数	5
詳細	binding site for residue MG C 401

鎖名	残基
C	ASP49
C	ASN84
C	HIS158
C	HIS186
C	MG402

---

site_id	AC5
残基数	5
詳細	binding site for residue MG C 402

鎖名	残基
C	ASP8
C	HIS10
C	ASP49
C	HIS188
C	MG401

---

site_id	AC6
残基数	21
詳細	binding site for residue AGS D 1101

鎖名	残基
B	TYR890
B	LEU910
B	ASN914
B	SER916
B	GLU919
D	LYS14
D	SER15
D	GLU33
D	GLY35
D	SER36
D	GLY37
D	LYS38
D	SER39
D	SER40
D	THR60
D	ILE62
D	THR63
D	LYS64
D	GLN134
D	GLU947
D	LYS994

---

SwissProt/UniProtに記載されている蛋白質分子機能情報

site_id	SWS_FT_FI1
残基数	2
詳細	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00449, ECO:0007744|PDB:3AUY

鎖名	残基	詳細
B	LYS14
D	LYS14

---

site_id	SWS_FT_FI2
残基数	4
詳細	BINDING: BINDING => ECO:0007744|PDB:3AUX, ECO:0007744|PDB:3AUY

鎖名	残基	詳細
B	GLY35
C	ASP49
C	ASN84
C	HIS158
C	HIS186
C	HIS188
B	ILE62
D	GLY35
D	ILE62
A	HIS158
A	HIS186
A	HIS188
C	ASP8
C	HIS10

---

site_id	SWS_FT_FI3
残基数	2
詳細	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00449

鎖名	残基	詳細
B	GLN134
D	GLN134

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