5DNA

Crystal structure of Candida boidinii formate dehydrogenase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0008863	molecular_function	formate dehydrogenase (NAD+) activity
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0042183	biological_process	formate catabolic process
A	0051287	molecular_function	NAD binding
B	0000166	molecular_function	nucleotide binding
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0008863	molecular_function	formate dehydrogenase (NAD+) activity
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0042183	biological_process	formate catabolic process
B	0051287	molecular_function	NAD binding
C	0000166	molecular_function	nucleotide binding
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005829	cellular_component	cytosol
C	0008863	molecular_function	formate dehydrogenase (NAD+) activity
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0042183	biological_process	formate catabolic process
C	0051287	molecular_function	NAD binding
D	0000166	molecular_function	nucleotide binding
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005829	cellular_component	cytosol
D	0008863	molecular_function	formate dehydrogenase (NAD+) activity
D	0016491	molecular_function	oxidoreductase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0042183	biological_process	formate catabolic process
D	0051287	molecular_function	NAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue SO4 A 401

Chain	Residue
A	GLN197
A	ALA198
A	ARG211
A	HOH514
A	HOH524
A	HOH613

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site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 402

Chain	Residue
A	HOH518
A	HOH744
A	GLY173
A	ARG174
A	HOH506

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site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 B 401

Chain	Residue
B	GLY173
B	ARG174
B	HOH547
B	HOH730
B	HOH774

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site_id	AC4
Number of Residues	6
Details	binding site for residue SO4 D 401

Chain	Residue
D	GLY173
D	ARG174
D	HOH502
D	HOH509
D	HOH572
D	HOH728

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site_id	AC5
Number of Residues	5
Details	binding site for residue SO4 D 402

Chain	Residue
D	GLN197
D	ALA198
D	ARG211
D	HOH503
D	HOH632

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Functional Information from PROSITE/UniProt

site_id	PS00065
Number of Residues	29
Details	D_2_HYDROXYACID_DH_1 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. IATIGaGRIGyrvlerlvpfnpkeLLyYD

Chain	Residue	Details
A	ILE167-ASP195

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site_id	PS00670
Number of Residues	23
Details	D_2_HYDROXYACID_DH_2 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. LVaqADIVtINaPlhagTkgLiN

Chain	Residue	Details
A	LEU218-ASN240

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site_id	PS00671
Number of Residues	17
Details	D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. FKkGaWLVNtARGaICV

Chain	Residue	Details
A	PHE247-VAL263

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