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4R62

Structure of Rad6~Ub

GO(遺伝子オントロジー)由来の情報
鎖名GO(遺伝子オントロジー)id名前空間内容
A0000166molecular_functionnucleotide binding
A0000209biological_processprotein polyubiquitination
A0000722biological_processtelomere maintenance via recombination
A0000724biological_processdouble-strand break repair via homologous recombination
A0000781cellular_componentchromosome, telomeric region
A0000785cellular_componentchromatin
A0003697molecular_functionsingle-stranded DNA binding
A0004842molecular_functionubiquitin-protein transferase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0006281biological_processDNA repair
A0006325biological_processchromatin organization
A0006353biological_processDNA-templated transcription termination
A0006366biological_processtranscription by RNA polymerase II
A0006511biological_processubiquitin-dependent protein catabolic process
A0006974biological_processDNA damage response
A0016567biological_processprotein ubiquitination
A0016740molecular_functiontransferase activity
A0017116molecular_functionsingle-stranded DNA helicase activity
A0019538biological_processprotein metabolic process
A0030435biological_processsporulation resulting in formation of a cellular spore
A0031509biological_processsubtelomeric heterochromatin formation
A0031571biological_processmitotic G1 DNA damage checkpoint signaling
A0032508biological_processDNA duplex unwinding
A0033503cellular_componentHULC complex
A0036503biological_processERAD pathway
A0042138biological_processmeiotic DNA double-strand break formation
A0042275biological_processerror-free postreplication DNA repair
A0042276biological_processerror-prone translesion synthesis
A0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
A0061631molecular_functionubiquitin conjugating enzyme activity
A0070628molecular_functionproteasome binding
A0070987biological_processerror-free translesion synthesis
A0071596biological_processubiquitin-dependent protein catabolic process via the N-end rule pathway
A0071629biological_processcytoplasm protein quality control by the ubiquitin-proteasome system
A0090089biological_processregulation of dipeptide transport
A0097505cellular_componentRad6-Rad18 complex
A0120174biological_processstress-induced homeostatically regulated protein degradation pathway
A1990303cellular_componentUBR1-RAD6 ubiquitin ligase complex
A1990304cellular_componentMUB1-RAD6-UBR2 ubiquitin ligase complex
A1990305cellular_componentRAD6-UBR2 ubiquitin ligase complex
PDBデータベースに由来する情報
site_idAC1
残基数3
詳細BINDING SITE FOR RESIDUE ACT A 201
鎖名残基
AHIS69
AVAL70
AILE87

UniProtにおけるモチーフ・データベースPROSITEからの機能情報
site_idPS00299
残基数26
詳細UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD
鎖名残基詳細
BLYS27-ASP52

SwissProt/UniProtに記載されている蛋白質分子機能情報
site_idSWS_FT_FI1
残基数2
詳細SITE: Interacts with activating enzyme
鎖名残基詳細
BARG54
BARG72

site_idSWS_FT_FI2
残基数1
詳細SITE: Essential for function
鎖名残基詳細
BHIS68

site_idSWS_FT_FI3
残基数1
詳細MOD_RES: Phosphoserine; by PINK1 => ECO:0000269|PubMed:24660806, ECO:0000269|PubMed:24751536, ECO:0000269|PubMed:24784582, ECO:0000269|PubMed:25527291
鎖名残基詳細
BSER65

site_idSWS_FT_FI4
残基数1
詳細MOD_RES: (Microbial infection) ADP-ribosylthreonine => ECO:0000269|PubMed:32330457
鎖名残基詳細
BTHR66

site_idSWS_FT_FI5
残基数1
詳細MOD_RES: ADP-ribosylglycine => ECO:0000269|PubMed:28525742
鎖名残基詳細
BGLY76

site_idSWS_FT_FI6
残基数1
詳細CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603
鎖名残基詳細
BLYS6

site_idSWS_FT_FI7
残基数2
詳細CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
鎖名残基詳細
BGLY76

site_idSWS_FT_FI8
残基数2
詳細CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144
鎖名残基詳細
BLYS11
BLYS48

site_idSWS_FT_FI9
残基数1
詳細CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860
鎖名残基詳細
BLYS27

site_idSWS_FT_FI10
残基数1
詳細CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:25752573, ECO:0000269|PubMed:25752577, ECO:0000269|PubMed:34239127
鎖名残基詳細
BLYS29

site_idSWS_FT_FI11
残基数1
詳細CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577
鎖名残基詳細
BLYS33

site_idSWS_FT_FI12
残基数1
詳細CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:18719106
鎖名残基詳細
BLYS63

CSAにおける酵素触媒機能の情報
site_idMCSA1
残基数1
詳細M-CSA 939
鎖名残基詳細
ALYS88nucleophile

218853

件を2024-04-24に公開中

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