4OMF

The F420-reducing [NiFe]-hydrogenase complex from Methanothermobacter marburgensis, the first X-ray structure of a group 3 family member

GO（遺伝子オントロジー）由来の情報

鎖名	GO（遺伝子オントロジー）id	名前空間	内容
A	0008901	molecular_function	ferredoxin hydrogenase activity
A	0016151	molecular_function	nickel cation binding
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
A	0050454	molecular_function	coenzyme F420 hydrogenase activity
A	0050660	molecular_function	flavin adenine dinucleotide binding
A	0051536	molecular_function	iron-sulfur cluster binding
B	0000166	molecular_function	nucleotide binding
B	0016151	molecular_function	nickel cation binding
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
B	0050454	molecular_function	coenzyme F420 hydrogenase activity
B	0050660	molecular_function	flavin adenine dinucleotide binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	0052592	molecular_function	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor
G	0016151	molecular_function	nickel cation binding
G	0016491	molecular_function	oxidoreductase activity
G	0046872	molecular_function	metal ion binding
G	0050454	molecular_function	coenzyme F420 hydrogenase activity
G	0050660	molecular_function	flavin adenine dinucleotide binding
G	0051536	molecular_function	iron-sulfur cluster binding
G	0051539	molecular_function	4 iron, 4 sulfur cluster binding

PDBデータベースに由来する情報

site_id	AC1
残基数	9
詳細	BINDING SITE FOR RESIDUE SF4 G 301

鎖名	残基
A	HIS150
G	GLY56
G	CYS57
G	ASP60
G	SER131
G	CYS132
G	PHE138
G	GLY170
G	CYS171

---

site_id	AC2
残基数	10
詳細	BINDING SITE FOR RESIDUE SF4 G 302

鎖名	残基
G	GLY207
G	CYS230
G	THR232
G	LEU235
G	LEU244
G	CYS249
G	ILE250
G	CYS252
G	GLY253
G	CYS255

---

site_id	AC3
残基数	8
詳細	BINDING SITE FOR RESIDUE SF4 G 303

鎖名	残基
G	CYS220
G	ILE221
G	GLY222
G	CYS223
G	GLY224
G	CYS226
G	CYS259
G	PRO260

---

site_id	AC4
残基数	6
詳細	BINDING SITE FOR RESIDUE DTZ G 304

鎖名	残基
G	CYS206
G	CYS206
G	CYS208
G	CYS208
G	LYS251
G	HOH565

---

site_id	AC5
残基数	5
詳細	BINDING SITE FOR RESIDUE MG A 501

鎖名	残基
A	GLU233
A	HOH666
A	HOH707
G	ALA148
G	HOH475

---

site_id	AC6
残基数	12
詳細	BINDING SITE FOR RESIDUE NFU A 502

鎖名	残基
A	CYS63
A	CYS66
A	HIS70
A	ALA326
A	PRO327
A	ARG328
A	ASP331
A	VAL349
A	PRO350
A	THR351
A	CYS380
A	CYS383

---

site_id	AC7
残基数	6
詳細	BINDING SITE FOR RESIDUE MG A 503

鎖名	残基
A	GLU44
A	ALA347
A	HIS386
A	HOH961
A	HOH962
A	HOH963

---

site_id	AC8
残基数	6
詳細	BINDING SITE FOR RESIDUE MG A 504

鎖名	残基
A	HOH601
A	HOH925
A	HOH926
A	HOH959
A	HOH965
A	HOH966

---

site_id	AC9
残基数	4
詳細	BINDING SITE FOR RESIDUE CL A 505

鎖名	残基
A	ILE156
A	ARG308
A	HOH683
A	HOH699

---

site_id	BC1
残基数	12
詳細	BINDING SITE FOR RESIDUE SF4 B 401

鎖名	残基
B	ILE102
B	PRO103
B	CYS104
B	CYS134
B	MET135
B	GLU136
B	ASN137
B	CYS192
B	CYS195
B	LYS261
G	ILE221
G	ARG261

---

site_id	BC2
残基数	6
詳細	BINDING SITE FOR RESIDUE MG B 402

鎖名	残基
B	HOH501
B	HOH570
B	HOH626
B	HOH660
B	HOH694
B	HOH695

---

site_id	BC3
残基数	4
詳細	BINDING SITE FOR RESIDUE KEN B 403

鎖名	残基
B	ARG110
B	GLN113
B	ILE126
B	ASP204

---

site_id	BC4
残基数	31
詳細	BINDING SITE FOR RESIDUE FAD B 405

鎖名	残基
B	GLY73
B	THR74
B	LYS75
B	TYR76
B	THR77
B	SER79
B	ASN81
B	TYR133
B	CYS134
B	MET135
B	GLU136
B	ASN137
B	TYR198
B	GLY208
B	SER209
B	VAL210
B	HOH507
B	HOH514
B	HOH591
B	HOH619
B	ALA23
B	GLN24
B	ASP25
B	GLY26
B	GLY27
B	ILE28
B	VAL29
B	THR30
B	VAL47
B	ALA48
B	ALA71

---

UniProtにおけるモチーフ・データベースPROSITEからの機能情報

site_id	PS00198
残基数	12
詳細	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiKCGiCYvQCP

鎖名	残基	詳細
G	CYS249-PRO260

---

site_id	PS00507
残基数	26
詳細	NI_HGENASE_L_1 Nickel-dependent hydrogenases large subunit signature 1. RGLEkmvtgkapetapvmvQRiCGVC

鎖名	残基	詳細
A	ARG41-CYS66

---

site_id	PS00508
残基数	10
詳細	NI_HGENASE_L_2 Nickel-dependent hydrogenases large subunit signature 2. YDPCLSCat.H

鎖名	残基	詳細
A	TYR377-HIS386

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