4OEF

Crystal Structure Analysis of FGF2-Disaccharide (S6I2) complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008083	molecular_function	growth factor activity

Functional Information from PROSITE/UniProt

site_id	PS00247
Number of Residues	24
Details	HBGF_FGF HBGF/FGF family signature. GrLlAsksvtd.ECfFfErlesnnY

Chain	Residue	Details
A	GLY80-TYR103

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ASN27

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	SITE: Important for interaction with integrin => ECO:0000269|PubMed:28302677

Chain	Residue	Details
A	LYS119
A	ARG120
A	LYS125

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphotyrosine; by TEC => ECO:0000269|PubMed:20230531

Chain	Residue	Details
A	TYR73

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0007744|PubMed:25114211

Chain	Residue	Details
A	LYS86

---