4DA4
Structure of mouse DNMT1 (731-1602) bound to hemimethylated CpG DNA
GO（遺伝子オントロジー）由来の情報
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 21 |
| 詳細 | BINDING SITE FOR RESIDUE SAH A 1701 |
| 鎖名 | 残基 |
| A | PHE1148 |
| A | ASP1193 |
| A | CYS1194 |
| A | GLY1226 |
| A | LYS1247 |
| A | LEU1250 |
| A | ALA1581 |
| A | VAL1582 |
| A | HOH1805 |
| A | HOH1808 |
| A | HOH1834 |
| A | SER1149 |
| A | HOH1900 |
| D | C4918 |
| A | GLY1150 |
| A | GLY1152 |
| A | GLY1153 |
| A | LEU1154 |
| A | GLU1171 |
| A | MET1172 |
| A | TRP1173 |
| site_id | AC2 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN A 1702 |
| 鎖名 | 残基 |
| A | CYS1479 |
| A | CYS1481 |
| A | CYS1487 |
| A | HIS1504 |
| site_id | AC3 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN A 1703 |
| 鎖名 | 残基 |
| A | HIS796 |
| A | CYS823 |
| A | CYS897 |
| A | CYS900 |
| site_id | AC4 |
| 残基数 | 23 |
| 詳細 | BINDING SITE FOR RESIDUE SAH B 1701 |
| 鎖名 | 残基 |
| B | PHE1148 |
| B | SER1149 |
| B | GLY1150 |
| B | GLY1152 |
| B | GLY1153 |
| B | LEU1154 |
| B | GLU1171 |
| B | MET1172 |
| B | TRP1173 |
| B | ASP1193 |
| B | CYS1194 |
| B | GLY1226 |
| B | LYS1247 |
| B | LEU1250 |
| B | ALA1581 |
| B | VAL1582 |
| B | HOH1875 |
| B | HOH1903 |
| B | HOH1940 |
| B | HOH1963 |
| B | HOH2009 |
| B | HOH2153 |
| F | C4918 |
| site_id | AC5 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN B 1702 |
| 鎖名 | 残基 |
| B | CYS1479 |
| B | CYS1481 |
| B | CYS1487 |
| B | HIS1504 |
| site_id | AC6 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN B 1703 |
| 鎖名 | 残基 |
| B | HIS796 |
| B | CYS823 |
| B | CYS897 |
| B | CYS900 |
| site_id | AC7 |
| 残基数 | 13 |
| 詳細 | BINDING SITE FOR RESIDUE CIT B 1704 |
| 鎖名 | 残基 |
| A | ARG1566 |
| A | PHE1568 |
| A | GLY1569 |
| A | ARG1574 |
| A | HOH1910 |
| A | HOH2182 |
| B | ARG1566 |
| B | PHE1567 |
| B | PHE1568 |
| B | GLY1569 |
| B | ARG1574 |
| B | HOH1840 |
| B | HOH2039 |
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 2 |
| 詳細 | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:17576694 |
| 鎖名 | 残基 | 詳細 |
| A | CYS1229 | |
| B | CYS1229 |
| site_id | SWS_FT_FI2 |
| 残基数 | 2 |
| 詳細 | BINDING: BINDING => ECO:0000269|PubMed:21163962, ECO:0007744|PDB:3PT6, ECO:0007744|PDB:4DA4 |
| 鎖名 | 残基 | 詳細 |
| A | SER1149 | |
| B | SER1149 |
| site_id | SWS_FT_FI3 |
| 残基数 | 6 |
| 詳細 | BINDING: BINDING => ECO:0000269|PubMed:21163962, ECO:0007744|PDB:3PT6, ECO:0007744|PDB:3PT9, ECO:0007744|PDB:4DA4 |
| 鎖名 | 残基 | 詳細 |
| A | GLY1153 | |
| A | GLU1171 | |
| A | VAL1582 | |
| B | GLY1153 | |
| B | GLU1171 | |
| B | VAL1582 |
| site_id | SWS_FT_FI4 |
| 残基数 | 2 |
| 詳細 | BINDING: BINDING => ECO:0000269|PubMed:21163962, ECO:0007744|PDB:3PT6, ECO:0007744|PDB:3PT9 |
| 鎖名 | 残基 | 詳細 |
| A | ASP1193 | |
| B | ASP1193 |
| site_id | SWS_FT_FI5 |
| 残基数 | 4 |
| 詳細 | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P26358 |
| 鎖名 | 残基 | 詳細 |
| A | SER735 | |
| A | SER882 | |
| B | SER735 | |
| B | SER882 |
| site_id | SWS_FT_FI6 |
| 残基数 | 22 |
| 詳細 | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P26358 |
| 鎖名 | 残基 | 詳細 |
| A | LYS752 | |
| A | LYS1352 | |
| A | LYS1418 | |
| B | LYS752 | |
| B | LYS895 | |
| B | LYS961 | |
| B | LYS965 | |
| B | LYS979 | |
| B | LYS1114 | |
| B | LYS1116 | |
| B | LYS1118 | |
| A | LYS895 | |
| B | LYS1120 | |
| B | LYS1352 | |
| B | LYS1418 | |
| A | LYS961 | |
| A | LYS965 | |
| A | LYS979 | |
| A | LYS1114 | |
| A | LYS1116 | |
| A | LYS1118 | |
| A | LYS1120 |
| site_id | SWS_FT_FI7 |
| 残基数 | 4 |
| 詳細 | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:23806337 |
| 鎖名 | 残基 | 詳細 |
| A | LYS1122 | |
| A | LYS1124 | |
| B | LYS1122 | |
| B | LYS1124 |
