4AQ3
HUMAN BCL-2 WITH PHENYLACYLSULFONAMIDE INHIBITOR
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0042981 | biological_process | regulation of apoptotic process |
| B | 0042981 | biological_process | regulation of apoptotic process |
| C | 0042981 | biological_process | regulation of apoptotic process |
| D | 0042981 | biological_process | regulation of apoptotic process |
| E | 0042981 | biological_process | regulation of apoptotic process |
| F | 0042981 | biological_process | regulation of apoptotic process |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 10 |
| 詳細 | BINDING SITE FOR RESIDUE 398 A 1163 |
| 鎖名 | 残基 |
| A | TYR67 |
| E | GLY162 |
| A | ASP70 |
| A | MET74 |
| A | GLU95 |
| A | LEU96 |
| A | ARG105 |
| E | GLN58 |
| E | LEU160 |
| E | TYR161 |
| site_id | AC2 |
| 残基数 | 15 |
| 詳細 | BINDING SITE FOR RESIDUE 398 B 1163 |
| 鎖名 | 残基 |
| B | PHE63 |
| B | TYR67 |
| B | ASP70 |
| B | PHE71 |
| B | MET74 |
| B | VAL92 |
| B | GLU95 |
| B | GLY104 |
| B | ALA108 |
| B | PHE112 |
| B | TYR161 |
| D | GLN58 |
| D | TYR161 |
| D | GLY162 |
| E | PRO82 |
| site_id | AC3 |
| 残基数 | 11 |
| 詳細 | BINDING SITE FOR RESIDUE 398 C 1163 |
| 鎖名 | 残基 |
| C | PHE63 |
| C | TYR67 |
| C | ASP70 |
| C | MET74 |
| C | GLU95 |
| C | LEU96 |
| C | TYR161 |
| D | PRO82 |
| F | GLN58 |
| F | TYR161 |
| F | GLY162 |
| site_id | AC4 |
| 残基数 | 11 |
| 詳細 | BINDING SITE FOR RESIDUE 398 D 1163 |
| 鎖名 | 残基 |
| A | PRO82 |
| B | GLN58 |
| B | LEU160 |
| B | TYR161 |
| B | GLY162 |
| D | PHE63 |
| D | TYR67 |
| D | ASP70 |
| D | MET74 |
| D | GLU95 |
| D | ALA108 |
| site_id | AC5 |
| 残基数 | 11 |
| 詳細 | BINDING SITE FOR RESIDUE 398 E 1163 |
| 鎖名 | 残基 |
| A | GLN58 |
| A | LEU160 |
| A | TYR161 |
| A | GLY162 |
| E | PHE63 |
| E | TYR67 |
| E | ASP70 |
| E | MET74 |
| E | VAL92 |
| E | GLU95 |
| E | ALA108 |
| site_id | AC6 |
| 残基数 | 11 |
| 詳細 | BINDING SITE FOR RESIDUE 398 F 1163 |
| 鎖名 | 残基 |
| B | PHE83 |
| C | GLN58 |
| C | LEU160 |
| C | TYR161 |
| C | GLY162 |
| F | PHE63 |
| F | TYR67 |
| F | ASP70 |
| F | VAL92 |
| F | GLU95 |
| F | ALA108 |
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
| site_id | PS01080 |
| 残基数 | 19 |
| 詳細 | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFeFGG |
| 鎖名 | 残基 | 詳細 |
| A | LEU96-GLY114 |
| site_id | PS01258 |
| 残基数 | 12 |
| 詳細 | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqdnGGWDaFV |
| 鎖名 | 残基 | 詳細 |
| A | TRP147-VAL158 |
| site_id | PS01259 |
| 残基数 | 15 |
| 詳細 | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VhlaLRqAGDDFSRR |
| 鎖名 | 残基 | 詳細 |
| A | VAL52-ARG66 |
| site_id | PS01260 |
| 残基数 | 21 |
| 詳細 | BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. DNREIVmKYIHYKLSQRGYeW |
| 鎖名 | 残基 | 詳細 |
| A | ASP10-TRP30 |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 6 |
| 詳細 | MOD_RES: Phosphothreonine; by MAPK8 => ECO:0000269|PubMed:18570871 |
| 鎖名 | 残基 | 詳細 |
| B | LEU54 | |
| F | LEU54 | |
| C | LEU54 | |
| D | LEU54 | |
| E | LEU54 | |
| A | LEU54 |
| site_id | SWS_FT_FI2 |
| 残基数 | 6 |
| 詳細 | MOD_RES: Phosphoserine; by MAPK8 and PKC => ECO:0000269|PubMed:18570871 |
| 鎖名 | 残基 | 詳細 |
| E | ALA55 | |
| B | ALA55 | |
| C | ALA55 | |
| D | ALA55 | |
| F | ALA55 | |
| A | ALA55 |
| site_id | SWS_FT_FI3 |
| 残基数 | 6 |
| 詳細 | MOD_RES: Phosphoserine; by MAPK8 => ECO:0000269|PubMed:18570871 |
| 鎖名 | 残基 | 詳細 |
| D | ALA72 | |
| F | ALA72 | |
| E | ALA72 | |
| A | ALA72 | |
| C | ALA72 | |
| B | ALA72 |
