3ZTS

Hexagonal form P6122 of the Aquifex aeolicus nucleoside diphosphate kinase (FINAL STAGE OF RADIATION DAMAGE)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006163	biological_process	purine nucleotide metabolic process
A	0006183	biological_process	GTP biosynthetic process
A	0006220	biological_process	pyrimidine nucleotide metabolic process
A	0006228	biological_process	UTP biosynthetic process
A	0006241	biological_process	CTP biosynthetic process
A	0009117	biological_process	nucleotide metabolic process
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016740	molecular_function	transferase activity
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0004550	molecular_function	nucleoside diphosphate kinase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006163	biological_process	purine nucleotide metabolic process
B	0006183	biological_process	GTP biosynthetic process
B	0006220	biological_process	pyrimidine nucleotide metabolic process
B	0006228	biological_process	UTP biosynthetic process
B	0006241	biological_process	CTP biosynthetic process
B	0009117	biological_process	nucleotide metabolic process
B	0016301	molecular_function	kinase activity
B	0016310	biological_process	phosphorylation
B	0016740	molecular_function	transferase activity
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0004550	molecular_function	nucleoside diphosphate kinase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006163	biological_process	purine nucleotide metabolic process
C	0006183	biological_process	GTP biosynthetic process
C	0006220	biological_process	pyrimidine nucleotide metabolic process
C	0006228	biological_process	UTP biosynthetic process
C	0006241	biological_process	CTP biosynthetic process
C	0009117	biological_process	nucleotide metabolic process
C	0016301	molecular_function	kinase activity
C	0016310	biological_process	phosphorylation
C	0016740	molecular_function	transferase activity
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0004550	molecular_function	nucleoside diphosphate kinase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006163	biological_process	purine nucleotide metabolic process
D	0006183	biological_process	GTP biosynthetic process
D	0006220	biological_process	pyrimidine nucleotide metabolic process
D	0006228	biological_process	UTP biosynthetic process
D	0006241	biological_process	CTP biosynthetic process
D	0009117	biological_process	nucleotide metabolic process
D	0016301	molecular_function	kinase activity
D	0016310	biological_process	phosphorylation
D	0016740	molecular_function	transferase activity
D	0046872	molecular_function	metal ion binding
E	0000166	molecular_function	nucleotide binding
E	0004550	molecular_function	nucleoside diphosphate kinase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0006163	biological_process	purine nucleotide metabolic process
E	0006183	biological_process	GTP biosynthetic process
E	0006220	biological_process	pyrimidine nucleotide metabolic process
E	0006228	biological_process	UTP biosynthetic process
E	0006241	biological_process	CTP biosynthetic process
E	0009117	biological_process	nucleotide metabolic process
E	0016301	molecular_function	kinase activity
E	0016310	biological_process	phosphorylation
E	0016740	molecular_function	transferase activity
E	0046872	molecular_function	metal ion binding
F	0000166	molecular_function	nucleotide binding
F	0004550	molecular_function	nucleoside diphosphate kinase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0006163	biological_process	purine nucleotide metabolic process
F	0006183	biological_process	GTP biosynthetic process
F	0006220	biological_process	pyrimidine nucleotide metabolic process
F	0006228	biological_process	UTP biosynthetic process
F	0006241	biological_process	CTP biosynthetic process
F	0009117	biological_process	nucleotide metabolic process
F	0016301	molecular_function	kinase activity
F	0016310	biological_process	phosphorylation
F	0016740	molecular_function	transferase activity
F	0046872	molecular_function	metal ion binding
G	0000166	molecular_function	nucleotide binding
G	0004550	molecular_function	nucleoside diphosphate kinase activity
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0006163	biological_process	purine nucleotide metabolic process
G	0006183	biological_process	GTP biosynthetic process
G	0006220	biological_process	pyrimidine nucleotide metabolic process
G	0006228	biological_process	UTP biosynthetic process
G	0006241	biological_process	CTP biosynthetic process
G	0009117	biological_process	nucleotide metabolic process
G	0016301	molecular_function	kinase activity
G	0016310	biological_process	phosphorylation
G	0016740	molecular_function	transferase activity
G	0046872	molecular_function	metal ion binding
H	0000166	molecular_function	nucleotide binding
H	0004550	molecular_function	nucleoside diphosphate kinase activity
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0006163	biological_process	purine nucleotide metabolic process
H	0006183	biological_process	GTP biosynthetic process
H	0006220	biological_process	pyrimidine nucleotide metabolic process
H	0006228	biological_process	UTP biosynthetic process
H	0006241	biological_process	CTP biosynthetic process
H	0009117	biological_process	nucleotide metabolic process
H	0016301	molecular_function	kinase activity
H	0016310	biological_process	phosphorylation
H	0016740	molecular_function	transferase activity
H	0046872	molecular_function	metal ion binding
I	0000166	molecular_function	nucleotide binding
I	0004550	molecular_function	nucleoside diphosphate kinase activity
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0006163	biological_process	purine nucleotide metabolic process
I	0006183	biological_process	GTP biosynthetic process
I	0006220	biological_process	pyrimidine nucleotide metabolic process
I	0006228	biological_process	UTP biosynthetic process
I	0006241	biological_process	CTP biosynthetic process
I	0009117	biological_process	nucleotide metabolic process
I	0016301	molecular_function	kinase activity
I	0016310	biological_process	phosphorylation
I	0016740	molecular_function	transferase activity
I	0046872	molecular_function	metal ion binding
J	0000166	molecular_function	nucleotide binding
J	0004550	molecular_function	nucleoside diphosphate kinase activity
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0006163	biological_process	purine nucleotide metabolic process
J	0006183	biological_process	GTP biosynthetic process
J	0006220	biological_process	pyrimidine nucleotide metabolic process
J	0006228	biological_process	UTP biosynthetic process
J	0006241	biological_process	CTP biosynthetic process
J	0009117	biological_process	nucleotide metabolic process
J	0016301	molecular_function	kinase activity
J	0016310	biological_process	phosphorylation
J	0016740	molecular_function	transferase activity
J	0046872	molecular_function	metal ion binding
K	0000166	molecular_function	nucleotide binding
K	0004550	molecular_function	nucleoside diphosphate kinase activity
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0006163	biological_process	purine nucleotide metabolic process
K	0006183	biological_process	GTP biosynthetic process
K	0006220	biological_process	pyrimidine nucleotide metabolic process
K	0006228	biological_process	UTP biosynthetic process
K	0006241	biological_process	CTP biosynthetic process
K	0009117	biological_process	nucleotide metabolic process
K	0016301	molecular_function	kinase activity
K	0016310	biological_process	phosphorylation
K	0016740	molecular_function	transferase activity
K	0046872	molecular_function	metal ion binding
L	0000166	molecular_function	nucleotide binding
L	0004550	molecular_function	nucleoside diphosphate kinase activity
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0006163	biological_process	purine nucleotide metabolic process
L	0006183	biological_process	GTP biosynthetic process
L	0006220	biological_process	pyrimidine nucleotide metabolic process
L	0006228	biological_process	UTP biosynthetic process
L	0006241	biological_process	CTP biosynthetic process
L	0009117	biological_process	nucleotide metabolic process
L	0016301	molecular_function	kinase activity
L	0016310	biological_process	phosphorylation
L	0016740	molecular_function	transferase activity
L	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00469
Number of Residues	9
Details	NDPK Nucleoside diphosphate kinase (NDPK) active site signature. NaiHASDSP

Chain	Residue	Details
A	ASN117-PRO125

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	ACT_SITE: Pros-phosphohistidine intermediate => ECO:0000255|HAMAP-Rule:MF_00451

Chain	Residue	Details
A	HIS120
B	HIS120
D	HIS120
E	HIS120
F	HIS120
G	HIS120
H	HIS120
I	HIS120
J	HIS120
K	HIS120
L	HIS120
C	HIS120

---

site_id	SWS_FT_FI2
Number of Residues	72
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00451

Chain	Residue	Details
A	LYS11
A	PHE59
A	ARG87
A	THR93
A	ARG107
A	ASN117
B	LYS11
B	PHE59
B	ARG87
B	THR93
B	ARG107
B	ASN117
C	LYS11
C	PHE59
C	ARG87
C	THR93
C	ARG107
C	ASN117
D	LYS11
D	PHE59
D	ARG87
D	THR93
D	ARG107
D	ASN117
E	LYS11
E	PHE59
E	ARG87
E	THR93
E	ARG107
E	ASN117
F	LYS11
F	PHE59
F	ARG87
F	THR93
F	ARG107
F	ASN117
G	LYS11
G	PHE59
G	ARG87
G	THR93
G	ARG107
G	ASN117
H	LYS11
H	PHE59
H	ARG87
H	THR93
H	ARG107
H	ASN117
I	LYS11
I	PHE59
I	ARG87
I	THR93
I	ARG107
I	ASN117
J	LYS11
J	PHE59
J	ARG87
J	THR93
J	ARG107
J	ASN117
K	LYS11
K	PHE59
K	ARG87
K	THR93
K	ARG107
K	ASN117
L	LYS11
L	PHE59
L	ARG87
L	THR93
L	ARG107
L	ASN117

---