3ZTO

Orthorhombic crystal form C222 of the Aquifex aeolicus nucleoside diphosphate kinase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006163	biological_process	purine nucleotide metabolic process
A	0006183	biological_process	GTP biosynthetic process
A	0006220	biological_process	pyrimidine nucleotide metabolic process
A	0006228	biological_process	UTP biosynthetic process
A	0006241	biological_process	CTP biosynthetic process
A	0009117	biological_process	nucleotide metabolic process
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016740	molecular_function	transferase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 200

Chain	Residue
A	LYS11
A	TYR51
A	HIS120
A	HOH2115
A	HOH2153
A	HOH2154
A	HOH2184
A	HOH2185

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 201

Chain	Residue
A	THR93
A	ARG107
A	HOH2139
A	HOH2153
A	HOH2154
A	ARG87

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Functional Information from PROSITE/UniProt

site_id	PS00469
Number of Residues	9
Details	NDPK Nucleoside diphosphate kinase (NDPK) active site signature. NaiHASDSP

Chain	Residue	Details
A	ASN117-PRO125

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Pros-phosphohistidine intermediate => ECO:0000255|HAMAP-Rule:MF_00451

Chain	Residue	Details
A	HIS120

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00451

Chain	Residue	Details
A	LYS11
A	PHE59
A	ARG87
A	THR93
A	ARG107
A	ASN117

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