3ZE5
Crystal structure of the integral membrane diacylglycerol kinase - delta4
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004143 | molecular_function | ATP-dependent diacylglycerol kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006654 | biological_process | phosphatidic acid biosynthetic process |
| A | 0008610 | biological_process | lipid biosynthetic process |
| A | 0008654 | biological_process | phospholipid biosynthetic process |
| A | 0009411 | biological_process | response to UV |
| A | 0016020 | cellular_component | membrane |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016310 | biological_process | phosphorylation |
| A | 0016740 | molecular_function | transferase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004143 | molecular_function | ATP-dependent diacylglycerol kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006654 | biological_process | phosphatidic acid biosynthetic process |
| B | 0008610 | biological_process | lipid biosynthetic process |
| B | 0008654 | biological_process | phospholipid biosynthetic process |
| B | 0009411 | biological_process | response to UV |
| B | 0016020 | cellular_component | membrane |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016310 | biological_process | phosphorylation |
| B | 0016740 | molecular_function | transferase activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004143 | molecular_function | ATP-dependent diacylglycerol kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006629 | biological_process | lipid metabolic process |
| C | 0006654 | biological_process | phosphatidic acid biosynthetic process |
| C | 0008610 | biological_process | lipid biosynthetic process |
| C | 0008654 | biological_process | phospholipid biosynthetic process |
| C | 0009411 | biological_process | response to UV |
| C | 0016020 | cellular_component | membrane |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016310 | biological_process | phosphorylation |
| C | 0016740 | molecular_function | transferase activity |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0046872 | molecular_function | metal ion binding |
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
| site_id | PS01069 |
| 残基数 | 12 |
| 詳細 | DAGK_PROKAR Prokaryotic diacylglycerol kinase signature. ElLNSAIEavVD |
| 鎖名 | 残基 | 詳細 |
| A | GLU69-ASP80 |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 87 |
| 詳細 | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:8071224 |
| 鎖名 | 残基 | 詳細 |
| A | ALA1-ALA30 | |
| B | ALA1-ALA30 | |
| C | ALA1-ALA30 |
| site_id | SWS_FT_FI2 |
| 残基数 | 99 |
| 詳細 | TRANSMEM: Helical => ECO:0000305|PubMed:12379131, ECO:0000305|PubMed:8071224 |
| 鎖名 | 残基 | 詳細 |
| A | PHE31-TRP47 | |
| A | ASP51-VAL68 | |
| B | PHE31-TRP47 | |
| B | ASP51-VAL68 | |
| C | PHE31-TRP47 | |
| C | ASP51-VAL68 |
| site_id | SWS_FT_FI3 |
| 残基数 | 6 |
| 詳細 | TOPO_DOM: Periplasmic => ECO:0000305|PubMed:12379131, ECO:0000305|PubMed:8071224 |
| 鎖名 | 残基 | 詳細 |
| A | LEU48-VAL50 | |
| B | LEU48-VAL50 | |
| C | LEU48-VAL50 |
| site_id | SWS_FT_FI4 |
| 残基数 | 75 |
| 詳細 | TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:8071224 |
| 鎖名 | 残基 | 詳細 |
| A | GLU69-LYS94 | |
| B | GLU69-LYS94 | |
| C | GLU69-LYS94 |
| site_id | SWS_FT_FI5 |
| 残基数 | 69 |
| 詳細 | TRANSMEM: Helical => ECO:0000305|PubMed:8071224 |
| 鎖名 | 残基 | 詳細 |
| A | ASP95-SER118 | |
| B | ASP95-SER118 | |
| C | ASP95-SER118 |
| site_id | SWS_FT_FI6 |
| 残基数 | 6 |
| 詳細 | TOPO_DOM: Periplasmic => ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:8071224 |
| 鎖名 | 残基 | 詳細 |
| A | HIS119-GLY121 | |
| B | HIS119-GLY121 | |
| C | HIS119-GLY121 |
| site_id | SWS_FT_FI7 |
| 残基数 | 3 |
| 詳細 | ACT_SITE: Proton acceptor => ECO:0000305|PubMed:26673816 |
| 鎖名 | 残基 | 詳細 |
| A | GLU69 | |
| B | GLU69 | |
| C | GLU69 |
| site_id | SWS_FT_FI8 |
| 残基数 | 3 |
| 詳細 | BINDING: BINDING => ECO:0000305|PubMed:25012698, ECO:0000305|PubMed:26673816, ECO:0000305|PubMed:26894538 |
| 鎖名 | 残基 | 詳細 |
| A | ARG9 | |
| B | ARG9 | |
| C | ARG9 |
| site_id | SWS_FT_FI9 |
| 残基数 | 3 |
| 詳細 | BINDING: BINDING => ECO:0000305|PubMed:23676677, ECO:0000305|PubMed:25012698, ECO:0000305|PubMed:26894538, ECO:0000305|PubMed:26960129 |
| 鎖名 | 残基 | 詳細 |
| A | ALA13 | |
| B | ALA13 | |
| C | ALA13 |
| site_id | SWS_FT_FI10 |
| 残基数 | 15 |
| 詳細 | BINDING: BINDING => ECO:0000305|PubMed:26673816, ECO:0000305|Ref.26 |
| 鎖名 | 残基 | 詳細 |
| A | TYR16 | |
| B | LYS94 | |
| C | TYR16 | |
| C | GLU28 | |
| C | GLU76 | |
| C | GLU85 | |
| C | LYS94 | |
| A | GLU28 | |
| A | GLU76 | |
| A | GLU85 | |
| A | LYS94 | |
| B | TYR16 | |
| B | GLU28 | |
| B | GLU76 | |
| B | GLU85 |
| site_id | SWS_FT_FI11 |
| 残基数 | 3 |
| 詳細 | BINDING: BINDING => ECO:0000305|PubMed:23676677, ECO:0000305|PubMed:25012698, ECO:0000305|PubMed:25055873, ECO:0000305|PubMed:26673816, ECO:0000305|PubMed:26960129 |
| 鎖名 | 残基 | 詳細 |
| A | ARG22 | |
| B | ARG22 | |
| C | ARG22 |
| site_id | SWS_FT_FI12 |
| 残基数 | 3 |
| 詳細 | BINDING: BINDING => ECO:0000305|PubMed:23676677, ECO:0000305|PubMed:25012698, ECO:0000305|PubMed:25055873, ECO:0000305|PubMed:26673816, ECO:0000305|PubMed:26894538, ECO:0000305|PubMed:26960129 |
| 鎖名 | 残基 | 詳細 |
| A | ALA30 | |
| B | ALA30 | |
| C | ALA30 |
| site_id | SWS_FT_FI13 |
| 残基数 | 3 |
| 詳細 | BINDING: BINDING => ECO:0000305|PubMed:23676677, ECO:0000305|PubMed:25012698, ECO:0000305|PubMed:26673816, ECO:0000305|PubMed:26894538, ECO:0000305|PubMed:26960129, ECO:0000305|Ref.25 |
| 鎖名 | 残基 | 詳細 |
| A | TRP47 | |
| B | TRP47 | |
| C | TRP47 |
| site_id | SWS_FT_FI14 |
| 残基数 | 3 |
| 詳細 | BINDING: BINDING => ECO:0000305|PubMed:23676677, ECO:0000305|PubMed:25012698, ECO:0000305|PubMed:25055873, ECO:0000305|PubMed:26673816, ECO:0000305|PubMed:26894538, ECO:0000305|PubMed:26960129, ECO:0000305|Ref.25 |
| 鎖名 | 残基 | 詳細 |
| A | ARG55 | |
| B | ARG55 | |
| C | ARG55 |
| site_id | SWS_FT_FI15 |
| 残基数 | 3 |
| 詳細 | BINDING: BINDING => ECO:0000305|PubMed:25012698, ECO:0000305|PubMed:26673816, ECO:0000305|PubMed:26894538, ECO:0000305|PubMed:26960129, ECO:0000305|Ref.26 |
| 鎖名 | 残基 | 詳細 |
| A | GLU69 | |
| B | GLU69 | |
| C | GLU69 |
| site_id | SWS_FT_FI16 |
| 残基数 | 3 |
| 詳細 | BINDING: BINDING => ECO:0000305|PubMed:23676677, ECO:0000305|PubMed:25012698, ECO:0000305|PubMed:26673816, ECO:0000305|PubMed:26894538, ECO:0000305|PubMed:26960129 |
| 鎖名 | 残基 | 詳細 |
| A | SER98 | |
| B | SER98 | |
| C | SER98 |
| site_id | SWS_FT_FI17 |
| 残基数 | 3 |
| 詳細 | BINDING: BINDING => ECO:0000305|PubMed:23676677, ECO:0000305|PubMed:25012698, ECO:0000305|PubMed:25055873, ECO:0000305|PubMed:26673816, ECO:0000305|PubMed:26894538, ECO:0000305|PubMed:26960129, ECO:0000305|Ref.26 |
| 鎖名 | 残基 | 詳細 |
| A | TRP112 | |
| B | TRP112 | |
| C | TRP112 |
