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3QZQ

Human enterovirus 71 3C protease mutant E71D in complex with rupintrivir

GO(遺伝子オントロジー)由来の情報
鎖名GO(遺伝子オントロジー)id名前空間内容
A0004197molecular_functioncysteine-type endopeptidase activity
A0005737cellular_componentcytoplasm
A0006508biological_processproteolysis
A0008233molecular_functionpeptidase activity
A0008234molecular_functioncysteine-type peptidase activity
A0016787molecular_functionhydrolase activity
A0030430cellular_componenthost cell cytoplasm
A0039618cellular_componentT=pseudo3 icosahedral viral capsid
B0004197molecular_functioncysteine-type endopeptidase activity
B0005737cellular_componentcytoplasm
B0006508biological_processproteolysis
B0008233molecular_functionpeptidase activity
B0008234molecular_functioncysteine-type peptidase activity
B0016787molecular_functionhydrolase activity
B0030430cellular_componenthost cell cytoplasm
B0039618cellular_componentT=pseudo3 icosahedral viral capsid
C0004197molecular_functioncysteine-type endopeptidase activity
C0005737cellular_componentcytoplasm
C0006508biological_processproteolysis
C0008233molecular_functionpeptidase activity
C0008234molecular_functioncysteine-type peptidase activity
C0016787molecular_functionhydrolase activity
C0030430cellular_componenthost cell cytoplasm
C0039618cellular_componentT=pseudo3 icosahedral viral capsid
D0004197molecular_functioncysteine-type endopeptidase activity
D0005737cellular_componentcytoplasm
D0006508biological_processproteolysis
D0008233molecular_functionpeptidase activity
D0008234molecular_functioncysteine-type peptidase activity
D0016787molecular_functionhydrolase activity
D0030430cellular_componenthost cell cytoplasm
D0039618cellular_componentT=pseudo3 icosahedral viral capsid
PDBデータベースに由来する情報
site_idAC1
残基数17
詳細BINDING SITE FOR RESIDUE AG7 A 501
鎖名残基
AARG39
AGLY145
ACYS147
AHIS161
AILE162
AGLY163
AGLY164
AASN165
APHE170
AHIS40
AASN126
ALEU127
ASER128
ALYS130
ATHR142
ALYS143
AALA144

site_idAC2
残基数20
詳細BINDING SITE FOR RESIDUE AG7 B 501
鎖名残基
ALEU53
BARG39
BHIS40
BTYR122
BLEU125
BASN126
BLEU127
BSER128
BLYS130
BTHR142
BLYS143
BALA144
BGLY145
BCYS147
BHIS161
BILE162
BGLY163
BGLY164
BASN165
BPHE170

site_idAC3
残基数20
詳細BINDING SITE FOR RESIDUE AG7 C 501
鎖名残基
CARG39
CHIS40
CLEU125
CASN126
CLEU127
CSER128
CLYS130
CTHR142
CLYS143
CALA144
CGLY145
CCYS147
CHIS161
CILE162
CGLY163
CGLY164
CASN165
CPHE170
CHOH194
CHOH198

site_idAC4
残基数21
詳細BINDING SITE FOR RESIDUE AG7 D 501
鎖名残基
BHOH193
DARG39
DHIS40
DLEU125
DASN126
DLEU127
DSER128
DLYS130
DTHR142
DLYS143
DALA144
DGLY145
DCYS147
DHIS161
DILE162
DGLY163
DGLY164
DASN165
DPHE170
DHOH258
DHOH479

218500

件を2024-04-17に公開中

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