3NO9
Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004333 | molecular_function | fumarate hydratase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0006106 | biological_process | fumarate metabolic process |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0016829 | molecular_function | lyase activity |
| A | 0045239 | cellular_component | tricarboxylic acid cycle heteromeric enzyme complex |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004333 | molecular_function | fumarate hydratase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0006106 | biological_process | fumarate metabolic process |
| B | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B | 0016829 | molecular_function | lyase activity |
| B | 0045239 | cellular_component | tricarboxylic acid cycle heteromeric enzyme complex |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004333 | molecular_function | fumarate hydratase activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006099 | biological_process | tricarboxylic acid cycle |
| C | 0006106 | biological_process | fumarate metabolic process |
| C | 0009274 | cellular_component | peptidoglycan-based cell wall |
| C | 0016829 | molecular_function | lyase activity |
| C | 0045239 | cellular_component | tricarboxylic acid cycle heteromeric enzyme complex |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004333 | molecular_function | fumarate hydratase activity |
| D | 0005576 | cellular_component | extracellular region |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0006099 | biological_process | tricarboxylic acid cycle |
| D | 0006106 | biological_process | fumarate metabolic process |
| D | 0009274 | cellular_component | peptidoglycan-based cell wall |
| D | 0016829 | molecular_function | lyase activity |
| D | 0045239 | cellular_component | tricarboxylic acid cycle heteromeric enzyme complex |
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 4 |
| 詳細 | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_00743, ECO:0000305|PubMed:22561013, ECO:0007744|PDB:4ADL, ECO:0007744|PDB:4ADM |
| 鎖名 | 残基 | 詳細 |
| A | HIS187 | |
| B | HIS187 | |
| C | HIS187 | |
| D | HIS187 |
| site_id | SWS_FT_FI2 |
| 残基数 | 4 |
| 詳細 | ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00743, ECO:0000269|PubMed:22561013, ECO:0007744|PDB:4ADM |
| 鎖名 | 残基 | 詳細 |
| A | SER318 | |
| B | SER318 | |
| C | SER318 | |
| D | SER318 |
| site_id | SWS_FT_FI3 |
| 残基数 | 4 |
| 詳細 | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00743, ECO:0000269|PubMed:22561013, ECO:0000269|PubMed:27325754, ECO:0007744|PDB:4ADL, ECO:0007744|PDB:4ADM, ECO:0007744|PDB:4APB, ECO:0007744|PDB:5F92 |
| 鎖名 | 残基 | 詳細 |
| A | SER104 | |
| B | SER104 | |
| C | SER104 | |
| D | SER104 |
| site_id | SWS_FT_FI4 |
| 残基数 | 4 |
| 詳細 | BINDING: in site B => ECO:0000255|HAMAP-Rule:MF_00743 |
| 鎖名 | 残基 | 詳細 |
| A | HIS128 | |
| B | HIS128 | |
| C | HIS128 | |
| D | HIS128 |
| site_id | SWS_FT_FI5 |
| 残基数 | 8 |
| 詳細 | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00743, ECO:0000269|PubMed:22561013, ECO:0000269|PubMed:27325754, ECO:0007744|PDB:4ADL, ECO:0007744|PDB:4ADM, ECO:0007744|PDB:4APB, ECO:0007744|PDB:5F91, ECO:0007744|PDB:5F92 |
| 鎖名 | 残基 | 詳細 |
| C | SER138 | |
| C | LYS324 | |
| D | SER138 | |
| D | LYS324 | |
| A | SER138 | |
| A | LYS324 | |
| B | SER138 | |
| B | LYS324 |
| site_id | SWS_FT_FI6 |
| 残基数 | 4 |
| 詳細 | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00743, ECO:0000269|PubMed:22561013, ECO:0000269|PubMed:27325754, ECO:0007744|PDB:4ADL, ECO:0007744|PDB:4APB, ECO:0007744|PDB:5F91, ECO:0007744|PDB:5F92 |
| 鎖名 | 残基 | 詳細 |
| A | THR186 | |
| B | THR186 | |
| C | THR186 | |
| D | THR186 |
| site_id | SWS_FT_FI7 |
| 残基数 | 4 |
| 詳細 | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00743, ECO:0000269|PubMed:22561013, ECO:0000269|PubMed:27325754, ECO:0007744|PDB:4ADL, ECO:0007744|PDB:4APB, ECO:0007744|PDB:5F92 |
| 鎖名 | 残基 | 詳細 |
| A | SER319 | |
| B | SER319 | |
| C | SER319 | |
| D | SER319 |
| site_id | SWS_FT_FI8 |
| 残基数 | 4 |
| 詳細 | SITE: Important for catalytic activity => ECO:0000255|HAMAP-Rule:MF_00743 |
| 鎖名 | 残基 | 詳細 |
| A | GLU331 | |
| B | GLU331 | |
| C | GLU331 | |
| D | GLU331 |
| site_id | SWS_FT_FI9 |
| 残基数 | 4 |
| 詳細 | MOD_RES: N-acetylalanine => ECO:0007744|PubMed:21969609 |
| 鎖名 | 残基 | 詳細 |
| A | ALA2 | |
| B | ALA2 | |
| C | ALA2 | |
| D | ALA2 |
