3J45
Structure of a non-translocating SecY protein channel with the 70S ribosome
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| E | 0006605 | biological_process | protein targeting |
| E | 0006886 | biological_process | intracellular protein transport |
| E | 0008320 | molecular_function | protein transmembrane transporter activity |
| E | 0009306 | biological_process | protein secretion |
| E | 0016020 | cellular_component | membrane |
| G | 0009306 | biological_process | protein secretion |
| G | 0015450 | molecular_function | protein-transporting ATPase activity |
| G | 0016020 | cellular_component | membrane |
| T | 0000027 | biological_process | ribosomal large subunit assembly |
| T | 0002181 | biological_process | cytoplasmic translation |
| T | 0003723 | molecular_function | RNA binding |
| T | 0003735 | molecular_function | structural constituent of ribosome |
| T | 0005515 | molecular_function | protein binding |
| T | 0005737 | cellular_component | cytoplasm |
| T | 0005840 | cellular_component | ribosome |
| T | 0006412 | biological_process | translation |
| T | 0019843 | molecular_function | rRNA binding |
| T | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| T | 1990904 | cellular_component | ribonucleoprotein complex |
| U | 0000027 | biological_process | ribosomal large subunit assembly |
| U | 0002181 | biological_process | cytoplasmic translation |
| U | 0003723 | molecular_function | RNA binding |
| U | 0003735 | molecular_function | structural constituent of ribosome |
| U | 0005515 | molecular_function | protein binding |
| U | 0005737 | cellular_component | cytoplasm |
| U | 0005829 | cellular_component | cytosol |
| U | 0005840 | cellular_component | ribosome |
| U | 0006412 | biological_process | translation |
| U | 0019843 | molecular_function | rRNA binding |
| U | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| U | 0070180 | molecular_function | large ribosomal subunit rRNA binding |
| U | 1990904 | cellular_component | ribonucleoprotein complex |
| Y | 0000027 | biological_process | ribosomal large subunit assembly |
| Y | 0002181 | biological_process | cytoplasmic translation |
| Y | 0003723 | molecular_function | RNA binding |
| Y | 0003735 | molecular_function | structural constituent of ribosome |
| Y | 0005737 | cellular_component | cytoplasm |
| Y | 0005840 | cellular_component | ribosome |
| Y | 0006412 | biological_process | translation |
| Y | 0019843 | molecular_function | rRNA binding |
| Y | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| Y | 1990904 | cellular_component | ribonucleoprotein complex |
| y | 0005048 | molecular_function | signal sequence binding |
| y | 0005515 | molecular_function | protein binding |
| y | 0005886 | cellular_component | plasma membrane |
| y | 0006605 | biological_process | protein targeting |
| y | 0006616 | biological_process | SRP-dependent cotranslational protein targeting to membrane, translocation |
| y | 0006886 | biological_process | intracellular protein transport |
| y | 0008320 | molecular_function | protein transmembrane transporter activity |
| y | 0015031 | biological_process | protein transport |
| y | 0016020 | cellular_component | membrane |
| y | 0031522 | cellular_component | cell envelope Sec protein transport complex |
| y | 0032978 | biological_process | protein insertion into membrane from inner side |
| y | 0043952 | biological_process | protein transport by the Sec complex |
| y | 0065002 | biological_process | intracellular protein transmembrane transport |
Functional Information from PROSITE/UniProt
| site_id | PS00430 |
| Number of Residues | 66 |
| Details | TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. mireerllkvlraphvsekastameksntivlkvakdatkaeikaavqklfevevevv.........................................................NTLVVKGK |
| Chain | Residue | Details |
| T | MET1-LYS66 |
| site_id | PS00579 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_L29 Ribosomal protein L29 signature. QSHLLKqVRRDVARV |
| Chain | Residue | Details |
| Y | GLN39-VAL53 |
| site_id | PS01108 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeViVLtGkdKGkr.GkV |
| Chain | Residue | Details |
| U | ASP7-VAL24 |
| site_id | PS00755 |
| Number of Residues | 20 |
| Details | SECY_1 Protein secY signature 1. SIFaLGImPYIsASIIIQLL |
| Chain | Residue | Details |
| y | SER76-LEU95 |
| site_id | PS00756 |
| Number of Residues | 18 |
| Details | SECY_2 Protein secY signature 2. WLgEqITer.GIGNGiSII |
| Chain | Residue | Details |
| y | TRP173-ILE190 |
| site_id | PS00050 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVTLKegqnldfV |
| Chain | Residue | Details |
| T | LYS81-VAL96 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 26 |
| Details | TRANSMEM: Helical => ECO:0000305 |
| Chain | Residue | Details |
| G | PHE51-ILE66 | |
| G | ILE14-GLY25 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:15919996 |
| Chain | Residue | Details |
| G | LYS26-ASN50 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 35 |
| Details | TRANSMEM: Discontinuously helical; Name=2 => ECO:0000250 |
| Chain | Residue | Details |
| y | ILE61-THR96 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 9 |
| Details | INTRAMEM: Helical; Name=Helix 2A => ECO:0000305 |
| Chain | Residue | Details |
| y | ILE61-GLY70 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 5 |
| Details | INTRAMEM: INTRAMEM => ECO:0000305 |
| Chain | Residue | Details |
| y | ALA71-SER76 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 19 |
| Details | INTRAMEM: Helical; Name=Helix 2B => ECO:0000305 |
| Chain | Residue | Details |
| y | ILE77-THR96 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 107 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305 |
| Chain | Residue | Details |
| y | VAL97-LYS115 | |
| y | THR179-ILE183 | |
| y | GLU238-GLY273 | |
| y | PHE330-TYR380 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 15 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000305 |
| Chain | Residue | Details |
| y | ILE116-GLN131 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 80 |
| Details | TOPO_DOM: Periplasmic => ECO:0000305 |
| Chain | Residue | Details |
| y | SER132-LEU164 | |
| y | PRO201-VAL223 | |
| y | ALA288-GLY313 | |
| y | LYS396 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 13 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000305 |
| Chain | Residue | Details |
| y | VAL165-ILE178 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 16 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000305 |
| Chain | Residue | Details |
| y | GLY184-PRO200 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 13 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000305 |
| Chain | Residue | Details |
| y | ALA224-VAL237 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 13 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000305 |
| Chain | Residue | Details |
| y | VAL274-PRO287 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 15 |
| Details | TRANSMEM: Helical; Name=8 => ECO:0000305 |
| Chain | Residue | Details |
| y | GLN314-CYS329 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 14 |
| Details | TRANSMEM: Helical; Name=9 => ECO:0000305 |
| Chain | Residue | Details |
| y | ILE381-MET395 |
| site_id | SWS_FT_FI16 |
| Number of Residues | 16 |
| Details | TRANSMEM: Helical; Name=10 => ECO:0000305 |
| Chain | Residue | Details |
| y | VAL397-ILE413 |
