3IQF

Structure of F420 dependent methylene-tetrahydromethanopterin dehydrogenase in complex with methenyl-tetrahydromethanopterin

GO（遺伝子オントロジー）由来の情報

鎖名	GO（遺伝子オントロジー）id	名前空間	内容
A	0006730	biological_process	one-carbon metabolic process
A	0008901	molecular_function	ferredoxin hydrogenase activity
A	0015948	biological_process	methanogenesis
A	0016491	molecular_function	oxidoreductase activity
A	0019386	biological_process	methanogenesis, from carbon dioxide
A	0030268	molecular_function	methylenetetrahydromethanopterin dehydrogenase activity
B	0006730	biological_process	one-carbon metabolic process
B	0008901	molecular_function	ferredoxin hydrogenase activity
B	0015948	biological_process	methanogenesis
B	0016491	molecular_function	oxidoreductase activity
B	0019386	biological_process	methanogenesis, from carbon dioxide
B	0030268	molecular_function	methylenetetrahydromethanopterin dehydrogenase activity
C	0006730	biological_process	one-carbon metabolic process
C	0008901	molecular_function	ferredoxin hydrogenase activity
C	0015948	biological_process	methanogenesis
C	0016491	molecular_function	oxidoreductase activity
C	0019386	biological_process	methanogenesis, from carbon dioxide
C	0030268	molecular_function	methylenetetrahydromethanopterin dehydrogenase activity
D	0006730	biological_process	one-carbon metabolic process
D	0008901	molecular_function	ferredoxin hydrogenase activity
D	0015948	biological_process	methanogenesis
D	0016491	molecular_function	oxidoreductase activity
D	0019386	biological_process	methanogenesis, from carbon dioxide
D	0030268	molecular_function	methylenetetrahydromethanopterin dehydrogenase activity
E	0006730	biological_process	one-carbon metabolic process
E	0008901	molecular_function	ferredoxin hydrogenase activity
E	0015948	biological_process	methanogenesis
E	0016491	molecular_function	oxidoreductase activity
E	0019386	biological_process	methanogenesis, from carbon dioxide
E	0030268	molecular_function	methylenetetrahydromethanopterin dehydrogenase activity
F	0006730	biological_process	one-carbon metabolic process
F	0008901	molecular_function	ferredoxin hydrogenase activity
F	0015948	biological_process	methanogenesis
F	0016491	molecular_function	oxidoreductase activity
F	0019386	biological_process	methanogenesis, from carbon dioxide
F	0030268	molecular_function	methylenetetrahydromethanopterin dehydrogenase activity
G	0006730	biological_process	one-carbon metabolic process
G	0008901	molecular_function	ferredoxin hydrogenase activity
G	0015948	biological_process	methanogenesis
G	0016491	molecular_function	oxidoreductase activity
G	0019386	biological_process	methanogenesis, from carbon dioxide
G	0030268	molecular_function	methylenetetrahydromethanopterin dehydrogenase activity
H	0006730	biological_process	one-carbon metabolic process
H	0008901	molecular_function	ferredoxin hydrogenase activity
H	0015948	biological_process	methanogenesis
H	0016491	molecular_function	oxidoreductase activity
H	0019386	biological_process	methanogenesis, from carbon dioxide
H	0030268	molecular_function	methylenetetrahydromethanopterin dehydrogenase activity
I	0006730	biological_process	one-carbon metabolic process
I	0008901	molecular_function	ferredoxin hydrogenase activity
I	0015948	biological_process	methanogenesis
I	0016491	molecular_function	oxidoreductase activity
I	0019386	biological_process	methanogenesis, from carbon dioxide
I	0030268	molecular_function	methylenetetrahydromethanopterin dehydrogenase activity
J	0006730	biological_process	one-carbon metabolic process
J	0008901	molecular_function	ferredoxin hydrogenase activity
J	0015948	biological_process	methanogenesis
J	0016491	molecular_function	oxidoreductase activity
J	0019386	biological_process	methanogenesis, from carbon dioxide
J	0030268	molecular_function	methylenetetrahydromethanopterin dehydrogenase activity
K	0006730	biological_process	one-carbon metabolic process
K	0008901	molecular_function	ferredoxin hydrogenase activity
K	0015948	biological_process	methanogenesis
K	0016491	molecular_function	oxidoreductase activity
K	0019386	biological_process	methanogenesis, from carbon dioxide
K	0030268	molecular_function	methylenetetrahydromethanopterin dehydrogenase activity
L	0006730	biological_process	one-carbon metabolic process
L	0008901	molecular_function	ferredoxin hydrogenase activity
L	0015948	biological_process	methanogenesis
L	0016491	molecular_function	oxidoreductase activity
L	0019386	biological_process	methanogenesis, from carbon dioxide
L	0030268	molecular_function	methylenetetrahydromethanopterin dehydrogenase activity

PDBデータベースに由来する情報

site_id	AC1
残基数	18
詳細	BINDING SITE FOR RESIDUE E4M A 284

鎖名	残基
A	ASN13
A	GLU130
A	ASN141
A	LEU144
A	CYS221
A	TYR230
A	HOH440
D	GLU26
D	ARG27
D	ALA28
A	LEU14
A	GLY15
A	VAL42
A	MET124
A	LEU125
A	ALA127
A	ARG128
A	ARG129

site_id	AC2
残基数	20
詳細	BINDING SITE FOR RESIDUE E4M B 284

鎖名	残基
B	ASN13
B	GLY15
B	VAL42
B	MET124
B	LEU125
B	ALA127
B	ARG128
B	ARG129
B	GLU130
B	ASN141
B	LEU144
B	CYS221
B	TYR230
B	HOH304
B	HOH576
B	HOH769
B	HOH1248
F	GLU26
F	ARG27
F	ALA28

site_id	AC3
残基数	20
詳細	BINDING SITE FOR RESIDUE E4M C 284

鎖名	残基
C	ASN13
C	GLY15
C	VAL42
C	MET124
C	LEU125
C	ALA127
C	ARG128
C	ARG129
C	GLU130
C	MET137
C	ASN141
C	LEU144
C	CYS221
C	TYR230
C	HOH286
C	HOH299
C	HOH1047
E	GLU26
E	ARG27
E	ALA28

site_id	AC4
残基数	19
詳細	BINDING SITE FOR RESIDUE E4M D 284

鎖名	残基
A	GLU26
A	ARG27
A	ALA28
D	ASN13
D	GLY15
D	VAL42
D	MET124
D	LEU125
D	ALA127
D	ARG128
D	ARG129
D	GLU130
D	ASN141
D	LEU144
D	CYS221
D	TYR230
D	HOH296
D	HOH777
D	HOH1172

site_id	AC5
残基数	20
詳細	BINDING SITE FOR RESIDUE E4M E 284

鎖名	残基
C	GLU26
C	ARG27
C	ALA28
C	HOH306
E	ASN13
E	GLY15
E	VAL42
E	MET124
E	LEU125
E	ALA127
E	ARG128
E	ARG129
E	GLU130
E	ASN141
E	LEU144
E	CYS221
E	TYR230
E	HOH305
E	HOH358
E	HOH578

site_id	AC6
残基数	4
詳細	BINDING SITE FOR RESIDUE CA E 285

鎖名	残基
E	GLU47
E	GLU50
B	GLU85
B	ASP89

site_id	AC7
残基数	18
詳細	BINDING SITE FOR RESIDUE E4M F 284

鎖名	残基
B	GLU26
B	ARG27
B	ALA28
B	HOH822
F	ASN13
F	GLY15
F	VAL42
F	MET124
F	LEU125
F	ALA127
F	ARG128
F	ARG129
F	GLU130
F	ASN141
F	CYS221
F	TYR230
F	HOH286
F	HOH1100

site_id	AC8
残基数	1
詳細	BINDING SITE FOR RESIDUE NA F 285

鎖名	残基
F	HOH1159

site_id	AC9
残基数	20
詳細	BINDING SITE FOR RESIDUE E4M G 284

鎖名	残基
G	ASN13
G	GLY15
G	VAL42
G	MET124
G	LEU125
G	ALA127
G	ARG128
G	ARG129
G	GLU130
G	ASN141
G	LEU144
G	CYS221
G	TYR230
G	HOH294
G	HOH303
G	HOH417
G	HOH947
J	GLU26
J	ARG27
J	ALA28

site_id	BC1
残基数	18
詳細	BINDING SITE FOR RESIDUE E4M H 284

鎖名	残基
H	ASN13
H	GLY15
H	MET124
H	LEU125
H	ALA127
H	ARG128
H	ARG129
H	GLU130
H	ASN141
H	LEU144
H	CYS221
H	TYR230
H	HOH306
H	HOH310
H	HOH735
H	HOH1237
L	GLU26
L	ARG27

site_id	BC2
残基数	20
詳細	BINDING SITE FOR RESIDUE E4M I 284

鎖名	残基
I	ASN13
I	GLY15
I	VAL42
I	MET124
I	LEU125
I	ALA127
I	ARG128
I	ARG129
I	GLU130
I	MET137
I	ASN141
I	LEU144
I	CYS221
I	TYR230
I	HOH306
I	HOH529
I	HOH764
I	HOH1225
K	GLU26
K	ARG27

site_id	BC3
残基数	7
詳細	BINDING SITE FOR RESIDUE CA I 285

鎖名	残基
I	ARG129
I	GLU130
I	PHE131
I	LEU132
I	ASP133
K	ARG263
K	PRO265

site_id	BC4
残基数	17
詳細	BINDING SITE FOR RESIDUE E4M J 284

鎖名	残基
G	GLU26
G	ARG27
J	ASN13
J	GLY15
J	MET124
J	LEU125
J	ALA127
J	ARG128
J	ARG129
J	GLU130
J	ASN141
J	LEU144
J	CYS221
J	TYR230
J	HOH298
J	HOH661
J	HOH684

site_id	BC5
残基数	6
詳細	BINDING SITE FOR RESIDUE CA J 285

鎖名	残基
J	SER257
J	ASN258
K	SER257
K	ASN258
L	SER257
L	ASN258

site_id	BC6
残基数	19
詳細	BINDING SITE FOR RESIDUE E4M K 284

鎖名	残基
I	GLU26
I	ARG27
I	ALA28
K	ASN13
K	GLY15
K	VAL42
K	MET124
K	LEU125
K	ALA127
K	ARG128
K	ARG129
K	GLU130
K	ASN141
K	LEU144
K	CYS221
K	TYR230
K	HOH295
K	HOH430
K	HOH783

site_id	BC7
残基数	4
詳細	BINDING SITE FOR RESIDUE CA K 285

鎖名	残基
H	GLU47
H	GLU50
K	GLU85
K	ASP89

site_id	BC8
残基数	6
詳細	BINDING SITE FOR RESIDUE CA K 286

鎖名	残基
K	ASP259
K	ALA260
K	VAL261
K	ARG276
K	PHE278
L	TYR198

site_id	BC9
残基数	19
詳細	BINDING SITE FOR RESIDUE E4M L 284

鎖名	残基
H	GLU26
H	ARG27
H	HOH305
L	ASN13
L	GLY15
L	VAL42
L	MET124
L	LEU125
L	ALA127
L	ARG128
L	ARG129
L	GLU130
L	ASN141
L	LEU144
L	CYS221
L	TYR230
L	HOH293
L	HOH808
L	HOH817

site_id	CC1
残基数	7
詳細	BINDING SITE FOR RESIDUE CA L 285

鎖名	残基
J	TYR198
L	ASP259
L	ALA260
L	VAL261
L	ARG276
L	PHE278
L	HOH1218

		Sequence (fasta)
		PDBx/mmCIF
		PDBML (ヘッダのみ (no-atom))
		PDB形式 (全ての情報)
		検証レポート (PDF)
		EDMap 2fo-fc (MTZ)