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3H0L

Structure of trna-dependent amidotransferase gatcab from aquifex aeolicus

GO(遺伝子オントロジー)由来の情報
鎖名GO(遺伝子オントロジー)id名前空間内容
A0000166molecular_functionnucleotide binding
A0003824molecular_functioncatalytic activity
A0005524molecular_functionATP binding
A0006412biological_processtranslation
A0016874molecular_functionligase activity
A0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
A0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
B0000166molecular_functionnucleotide binding
B0003824molecular_functioncatalytic activity
B0005524molecular_functionATP binding
B0006412biological_processtranslation
B0016874molecular_functionligase activity
B0016884molecular_functioncarbon-nitrogen ligase activity, with glutamine as amido-N-donor
B0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
B0050566molecular_functionasparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
B0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
B0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
C0000166molecular_functionnucleotide binding
C0005524molecular_functionATP binding
C0006412biological_processtranslation
C0006450biological_processregulation of translational fidelity
C0016874molecular_functionligase activity
C0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
C0050566molecular_functionasparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
C0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
C0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
D0000166molecular_functionnucleotide binding
D0003824molecular_functioncatalytic activity
D0005524molecular_functionATP binding
D0006412biological_processtranslation
D0016874molecular_functionligase activity
D0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
D0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
E0000166molecular_functionnucleotide binding
E0003824molecular_functioncatalytic activity
E0005524molecular_functionATP binding
E0006412biological_processtranslation
E0016874molecular_functionligase activity
E0016884molecular_functioncarbon-nitrogen ligase activity, with glutamine as amido-N-donor
E0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
E0050566molecular_functionasparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
E0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
E0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
F0000166molecular_functionnucleotide binding
F0005524molecular_functionATP binding
F0006412biological_processtranslation
F0006450biological_processregulation of translational fidelity
F0016874molecular_functionligase activity
F0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
F0050566molecular_functionasparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
F0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
F0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
G0000166molecular_functionnucleotide binding
G0003824molecular_functioncatalytic activity
G0005524molecular_functionATP binding
G0006412biological_processtranslation
G0016874molecular_functionligase activity
G0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
G0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
H0000166molecular_functionnucleotide binding
H0003824molecular_functioncatalytic activity
H0005524molecular_functionATP binding
H0006412biological_processtranslation
H0016874molecular_functionligase activity
H0016884molecular_functioncarbon-nitrogen ligase activity, with glutamine as amido-N-donor
H0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
H0050566molecular_functionasparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
H0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
H0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
I0000166molecular_functionnucleotide binding
I0005524molecular_functionATP binding
I0006412biological_processtranslation
I0006450biological_processregulation of translational fidelity
I0016874molecular_functionligase activity
I0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
I0050566molecular_functionasparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
I0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
I0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
J0000166molecular_functionnucleotide binding
J0003824molecular_functioncatalytic activity
J0005524molecular_functionATP binding
J0006412biological_processtranslation
J0016874molecular_functionligase activity
J0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
J0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
K0000166molecular_functionnucleotide binding
K0003824molecular_functioncatalytic activity
K0005524molecular_functionATP binding
K0006412biological_processtranslation
K0016874molecular_functionligase activity
K0016884molecular_functioncarbon-nitrogen ligase activity, with glutamine as amido-N-donor
K0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
K0050566molecular_functionasparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
K0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
K0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
L0000166molecular_functionnucleotide binding
L0005524molecular_functionATP binding
L0006412biological_processtranslation
L0006450biological_processregulation of translational fidelity
L0016874molecular_functionligase activity
L0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
L0050566molecular_functionasparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
L0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
L0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
M0000166molecular_functionnucleotide binding
M0003824molecular_functioncatalytic activity
M0005524molecular_functionATP binding
M0006412biological_processtranslation
M0016874molecular_functionligase activity
M0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
M0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
N0000166molecular_functionnucleotide binding
N0003824molecular_functioncatalytic activity
N0005524molecular_functionATP binding
N0006412biological_processtranslation
N0016874molecular_functionligase activity
N0016884molecular_functioncarbon-nitrogen ligase activity, with glutamine as amido-N-donor
N0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
N0050566molecular_functionasparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
N0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
N0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
O0000166molecular_functionnucleotide binding
O0005524molecular_functionATP binding
O0006412biological_processtranslation
O0006450biological_processregulation of translational fidelity
O0016874molecular_functionligase activity
O0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
O0050566molecular_functionasparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
O0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
O0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
P0000166molecular_functionnucleotide binding
P0003824molecular_functioncatalytic activity
P0005524molecular_functionATP binding
P0006412biological_processtranslation
P0016874molecular_functionligase activity
P0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
P0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
Q0000166molecular_functionnucleotide binding
Q0003824molecular_functioncatalytic activity
Q0005524molecular_functionATP binding
Q0006412biological_processtranslation
Q0016874molecular_functionligase activity
Q0016884molecular_functioncarbon-nitrogen ligase activity, with glutamine as amido-N-donor
Q0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
Q0050566molecular_functionasparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
Q0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
Q0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
R0000166molecular_functionnucleotide binding
R0005524molecular_functionATP binding
R0006412biological_processtranslation
R0006450biological_processregulation of translational fidelity
R0016874molecular_functionligase activity
R0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
R0050566molecular_functionasparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
R0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
R0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
S0000166molecular_functionnucleotide binding
S0003824molecular_functioncatalytic activity
S0005524molecular_functionATP binding
S0006412biological_processtranslation
S0016874molecular_functionligase activity
S0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
S0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
T0000166molecular_functionnucleotide binding
T0003824molecular_functioncatalytic activity
T0005524molecular_functionATP binding
T0006412biological_processtranslation
T0016874molecular_functionligase activity
T0016884molecular_functioncarbon-nitrogen ligase activity, with glutamine as amido-N-donor
T0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
T0050566molecular_functionasparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
T0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
T0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
U0000166molecular_functionnucleotide binding
U0005524molecular_functionATP binding
U0006412biological_processtranslation
U0006450biological_processregulation of translational fidelity
U0016874molecular_functionligase activity
U0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
U0050566molecular_functionasparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
U0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
U0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
V0000166molecular_functionnucleotide binding
V0003824molecular_functioncatalytic activity
V0005524molecular_functionATP binding
V0006412biological_processtranslation
V0016874molecular_functionligase activity
V0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
V0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
W0000166molecular_functionnucleotide binding
W0003824molecular_functioncatalytic activity
W0005524molecular_functionATP binding
W0006412biological_processtranslation
W0016874molecular_functionligase activity
W0016884molecular_functioncarbon-nitrogen ligase activity, with glutamine as amido-N-donor
W0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
W0050566molecular_functionasparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
W0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
W0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
X0000166molecular_functionnucleotide binding
X0005524molecular_functionATP binding
X0006412biological_processtranslation
X0006450biological_processregulation of translational fidelity
X0016874molecular_functionligase activity
X0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
X0050566molecular_functionasparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
X0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
X0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
PDBデータベースに由来する情報
site_idAC1
残基数12
詳細BINDING SITE FOR RESIDUE ADP B 701
鎖名残基
BVAL8
BSER199
BGLY209
BARG211
BGLY10
BLEU11
BGLU12
BVAL155
BTHR156
BGLU157
BPRO158
BASN197

site_idAC2
残基数3
詳細BINDING SITE FOR RESIDUE MG B 801
鎖名残基
BHIS14
BGLU127
BGLU153

site_idAC3
残基数4
詳細BINDING SITE FOR RESIDUE ZN B 901
鎖名残基
BCYS25
BCYS27
BCYS40
BCYS43

site_idAC4
残基数12
詳細BINDING SITE FOR RESIDUE ADP E 702
鎖名残基
EVAL8
EGLY10
ELEU11
EGLU12
EVAL155
ETHR156
EGLU157
EPRO158
EASN197
ESER199
EGLY209
EARG211

site_idAC5
残基数3
詳細BINDING SITE FOR RESIDUE MG E 802
鎖名残基
EHIS14
EGLU127
EGLU153

site_idAC6
残基数4
詳細BINDING SITE FOR RESIDUE ZN E 902
鎖名残基
ECYS25
ECYS27
ECYS40
ECYS43

site_idAC7
残基数12
詳細BINDING SITE FOR RESIDUE ADP H 703
鎖名残基
HVAL8
HGLY10
HLEU11
HGLU12
HVAL155
HTHR156
HGLU157
HPRO158
HASN197
HSER199
HGLY209
HARG211

site_idAC8
残基数3
詳細BINDING SITE FOR RESIDUE MG H 803
鎖名残基
HHIS14
HGLU127
HGLU153

site_idAC9
残基数4
詳細BINDING SITE FOR RESIDUE ZN H 903
鎖名残基
HCYS25
HCYS27
HCYS40
HCYS43

site_idBC1
残基数12
詳細BINDING SITE FOR RESIDUE ADP K 704
鎖名残基
KVAL8
KGLY10
KLEU11
KGLU12
KVAL155
KTHR156
KGLU157
KPRO158
KASN197
KSER199
KGLY209
KARG211

site_idBC2
残基数3
詳細BINDING SITE FOR RESIDUE MG K 804
鎖名残基
KHIS14
KGLU127
KGLU153

site_idBC3
残基数4
詳細BINDING SITE FOR RESIDUE ZN K 904
鎖名残基
KCYS25
KCYS27
KCYS40
KCYS43

site_idBC4
残基数12
詳細BINDING SITE FOR RESIDUE ADP N 705
鎖名残基
NVAL8
NGLY10
NLEU11
NGLU12
NVAL155
NTHR156
NGLU157
NPRO158
NASN197
NSER199
NGLY209
NARG211

site_idBC5
残基数3
詳細BINDING SITE FOR RESIDUE MG N 805
鎖名残基
NHIS14
NGLU127
NGLU153

site_idBC6
残基数4
詳細BINDING SITE FOR RESIDUE ZN N 905
鎖名残基
NCYS25
NCYS27
NCYS40
NCYS43

site_idBC7
残基数13
詳細BINDING SITE FOR RESIDUE ADP Q 706
鎖名残基
QVAL155
QTHR156
QGLU157
QPRO158
QASN197
QVAL198
QSER199
QGLY209
QARG211
QVAL8
QGLY10
QLEU11
QGLU12

site_idBC8
残基数3
詳細BINDING SITE FOR RESIDUE MG Q 806
鎖名残基
QHIS14
QGLU127
QGLU153

site_idBC9
残基数4
詳細BINDING SITE FOR RESIDUE ZN Q 906
鎖名残基
QCYS25
QCYS27
QCYS40
QCYS43

site_idCC1
残基数12
詳細BINDING SITE FOR RESIDUE ADP T 707
鎖名残基
TVAL8
TGLY10
TLEU11
TGLU12
TVAL155
TTHR156
TGLU157
TPRO158
TASN197
TSER199
TGLY209
TARG211

site_idCC2
残基数3
詳細BINDING SITE FOR RESIDUE MG T 807
鎖名残基
THIS14
TGLU127
TGLU153

site_idCC3
残基数4
詳細BINDING SITE FOR RESIDUE ZN T 907
鎖名残基
TCYS25
TCYS27
TCYS40
TCYS43

site_idCC4
残基数12
詳細BINDING SITE FOR RESIDUE ADP W 708
鎖名残基
WVAL8
WGLY10
WLEU11
WGLU12
WVAL155
WTHR156
WGLU157
WPRO158
WASN197
WSER199
WGLY209
WARG211

site_idCC5
残基数3
詳細BINDING SITE FOR RESIDUE MG W 808
鎖名残基
WHIS14
WGLU127
WGLU153

site_idCC6
残基数4
詳細BINDING SITE FOR RESIDUE ZN W 908
鎖名残基
WCYS25
WCYS27
WCYS40
WCYS43

site_idCC7
残基数11
詳細BINDING SITE FOR RESIDUE ASN A 901
鎖名残基
AALA121
AGLY123
ASER124
ASER147
AGLY169
AGLY170
ASER171
ATYR302
ATYR303
AARG351
AASP418

site_idCC8
残基数11
詳細BINDING SITE FOR RESIDUE ASN D 902
鎖名残基
DALA121
DMET122
DGLY123
DSER124
DGLY169
DGLY170
DSER171
DPHE199
DTYR302
DARG351
DASP418

site_idCC9
残基数11
詳細BINDING SITE FOR RESIDUE ASN G 903
鎖名残基
GALA121
GGLY123
GSER124
GTHR168
GGLY169
GGLY170
GSER171
GPHE199
GTYR302
GARG351
GASP418

site_idDC1
残基数12
詳細BINDING SITE FOR RESIDUE ASN J 904
鎖名残基
JALA121
JMET122
JGLY123
JSER124
JTHR168
JGLY169
JGLY170
JSER171
JPHE199
JTYR302
JARG351
JASP418

site_idDC2
残基数11
詳細BINDING SITE FOR RESIDUE ASN M 905
鎖名残基
MALA121
MMET122
MGLY123
MSER124
MGLY169
MGLY170
MSER171
MTYR302
MTYR303
MARG351
MASP418

site_idDC3
残基数13
詳細BINDING SITE FOR RESIDUE ASN P 906
鎖名残基
PALA121
PMET122
PGLY123
PSER124
PSER147
PTHR168
PGLY169
PGLY170
PSER171
PPHE199
PTYR302
PARG351
PASP418

site_idDC4
残基数12
詳細BINDING SITE FOR RESIDUE ASN S 907
鎖名残基
SALA121
SMET122
SGLY123
SSER124
STHR168
SGLY169
SGLY170
SSER171
SPHE199
STYR302
SARG351
SASP418

site_idDC5
残基数9
詳細BINDING SITE FOR RESIDUE ASN V 908
鎖名残基
VALA121
VGLY123
VGLY169
VGLY170
VSER171
VPHE199
VTYR302
VARG351
VASP418

UniProtにおけるモチーフ・データベースPROSITEからの機能情報
site_idPS00571
残基数32
詳細AMIDASES Amidases signature. GGSSGGsAAsVAvlsapvSlGsDtGgSIRqPA
鎖名残基詳細
AGLY145-ALA176

site_idPS01234
残基数15
詳細GATB Glutamyl-tRNA(Gln) amidotransferase subunit B signature. LNRagtPLMEIvTeP
鎖名残基詳細
BLEU144-PRO158

SwissProt/UniProtに記載されている蛋白質分子機能情報
site_idSWS_FT_FI1
残基数16
詳細ACT_SITE: Charge relay system => ECO:0000250
鎖名残基詳細
ALYS72
MSER147
PLYS72
PSER147
SLYS72
SSER147
VLYS72
VSER147
ASER147
DLYS72
DSER147
GLYS72
GSER147
JLYS72
JSER147
MLYS72

site_idSWS_FT_FI2
残基数8
詳細ACT_SITE: Acyl-ester intermediate => ECO:0000250
鎖名残基詳細
ASER171
DSER171
GSER171
JSER171
MSER171
PSER171
SSER171
VSER171

217705

件を2024-03-27に公開中

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