3FJX
E. coli EPSP synthase (T97I) liganded with S3P
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| A | 0003866 | molecular_function | 3-phosphoshikimate 1-carboxyvinyltransferase activity |
| A | 0004764 | molecular_function | shikimate 3-dehydrogenase (NADP+) activity |
| A | 0004765 | molecular_function | shikimate kinase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 16 |
| 詳細 | BINDING SITE FOR RESIDUE S3P A 428 |
| 鎖名 | 残基 |
| A | LYS22 |
| A | ASP313 |
| A | ASN336 |
| A | LYS340 |
| A | FMT429 |
| A | HOH462 |
| A | HOH470 |
| A | HOH780 |
| A | SER23 |
| A | ARG27 |
| A | ILE97 |
| A | SER169 |
| A | SER170 |
| A | GLN171 |
| A | SER197 |
| A | TYR200 |
| site_id | AC2 |
| 残基数 | 7 |
| 詳細 | BINDING SITE FOR RESIDUE FMT A 429 |
| 鎖名 | 残基 |
| A | LYS22 |
| A | ASP313 |
| A | GLU341 |
| A | ARG344 |
| A | HIS385 |
| A | ARG386 |
| A | S3P428 |
| site_id | AC3 |
| 残基数 | 5 |
| 詳細 | BINDING SITE FOR RESIDUE FMT A 430 |
| 鎖名 | 残基 |
| A | ALA380 |
| A | TYR382 |
| A | HOH511 |
| A | HOH681 |
| A | HOH751 |
| site_id | AC4 |
| 残基数 | 7 |
| 詳細 | BINDING SITE FOR RESIDUE FMT A 431 |
| 鎖名 | 残基 |
| A | LYS373 |
| A | LEU374 |
| A | SER397 |
| A | ASP398 |
| A | HOH589 |
| A | HOH767 |
| A | HOH782 |
| site_id | AC5 |
| 残基数 | 8 |
| 詳細 | BINDING SITE FOR RESIDUE FMT A 432 |
| 鎖名 | 残基 |
| A | LYS22 |
| A | ASN94 |
| A | GLY96 |
| A | ILE97 |
| A | ARG124 |
| A | GLU341 |
| A | LYS411 |
| A | HOH588 |
| site_id | AC6 |
| 残基数 | 5 |
| 詳細 | BINDING SITE FOR RESIDUE FMT A 433 |
| 鎖名 | 残基 |
| A | TYR335 |
| A | VAL339 |
| A | HOH642 |
| A | HOH660 |
| A | HOH709 |
| site_id | AC7 |
| 残基数 | 5 |
| 詳細 | BINDING SITE FOR RESIDUE FMT A 434 |
| 鎖名 | 残基 |
| A | THR58 |
| A | VAL62 |
| A | SER63 |
| A | TYR64 |
| A | HOH748 |
| site_id | AC8 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE FMT A 435 |
| 鎖名 | 残基 |
| A | THR65 |
| A | LEU66 |
| A | SER67 |
| A | ARG72 |
| site_id | AC9 |
| 残基数 | 5 |
| 詳細 | BINDING SITE FOR RESIDUE FMT A 436 |
| 鎖名 | 残基 |
| A | ARG298 |
| A | GLU300 |
| A | LEU301 |
| A | PHE324 |
| A | HOH716 |
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 1 |
| 詳細 | ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00210, ECO:0000269|PubMed:11171958, ECO:0000269|PubMed:12430021, ECO:0000269|PubMed:15736934, ECO:0000269|PubMed:16225867, ECO:0000269|PubMed:17855366, ECO:0000269|PubMed:17958399, ECO:0000269|PubMed:19211556 |
| 鎖名 | 残基 | 詳細 |
| A | ASP313 |
| site_id | SWS_FT_FI2 |
| 残基数 | 1 |
| 詳細 | ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00210, ECO:0000269|PubMed:15736934, ECO:0000305|PubMed:11171958 |
| 鎖名 | 残基 | 詳細 |
| A | GLU341 |
| site_id | SWS_FT_FI3 |
| 残基数 | 3 |
| 詳細 | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00210, ECO:0000269|PubMed:11171958, ECO:0000269|PubMed:12430021, ECO:0000269|PubMed:13129913, ECO:0000269|PubMed:15736934, ECO:0000269|PubMed:16225867, ECO:0000269|PubMed:17855366, ECO:0000269|PubMed:17958399, ECO:0000269|PubMed:19211556 |
| 鎖名 | 残基 | 詳細 |
| A | LYS22 | |
| A | SER169 | |
| A | LYS340 |
| site_id | SWS_FT_FI4 |
| 残基数 | 3 |
| 詳細 | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00210, ECO:0000269|PubMed:11171958, ECO:0000269|PubMed:12430021, ECO:0000269|PubMed:13129913, ECO:0000269|PubMed:15736934, ECO:0000269|PubMed:17855366, ECO:0000269|PubMed:17958399, ECO:0000269|PubMed:19211556 |
| 鎖名 | 残基 | 詳細 |
| A | ARG27 | |
| A | SER197 | |
| A | ASN336 |
| site_id | SWS_FT_FI5 |
| 残基数 | 4 |
| 詳細 | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00210, ECO:0000269|PubMed:11171958, ECO:0000269|PubMed:16225867, ECO:0000269|PubMed:17855366, ECO:0000269|PubMed:19211556 |
| 鎖名 | 残基 | 詳細 |
| A | ARG124 | |
| A | ARG344 | |
| A | ARG386 | |
| A | LYS411 |
| site_id | SWS_FT_FI6 |
| 残基数 | 2 |
| 詳細 | SITE: Modified by bromopyruvate => ECO:0000269|PubMed:11171958 |
| 鎖名 | 残基 | 詳細 |
| A | CYS408 | |
| A | LYS411 |
CSAにおける酵素触媒機能の情報
| site_id | MCSA1 |
| 残基数 | 7 |
| 詳細 | M-CSA 457 |
| 鎖名 | 残基 | 詳細 |
| A | ASP49 | metal ligand |
| A | ASN94 | metal ligand |
| A | ASP313 | electrostatic stabiliser, proton shuttle (general acid/base) |
| A | GLU341 | electrostatic stabiliser, metal ligand, proton shuttle (general acid/base) |
| A | HIS385 | steric role |
| A | ARG386 | transition state stabiliser |
| A | LYS411 | steric role |
