2XSH

CRYSTAL STRUCTURE OF P4 VARIANT OF BIPHENYL DIOXYGENASE FROM BURKHOLDERIA XENOVORANS LB400 IN COMPLEX WITH 2,6 DI CHLOROBIPHENYL

GO（遺伝子オントロジー）由来の情報

鎖名	GO（遺伝子オントロジー）id	名前空間	内容
A	0005506	molecular_function	iron ion binding
A	0016491	molecular_function	oxidoreductase activity
A	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
A	0019439	biological_process	obsolete aromatic compound catabolic process
A	0044237	biological_process	cellular metabolic process
A	0046872	molecular_function	metal ion binding
A	0051213	molecular_function	dioxygenase activity
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
B	0006725	biological_process	obsolete cellular aromatic compound metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
B	0019380	biological_process	3-phenylpropionate catabolic process
B	0019439	biological_process	obsolete aromatic compound catabolic process
B	0051213	molecular_function	dioxygenase activity
C	0005506	molecular_function	iron ion binding
C	0016491	molecular_function	oxidoreductase activity
C	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
C	0019439	biological_process	obsolete aromatic compound catabolic process
C	0044237	biological_process	cellular metabolic process
C	0046872	molecular_function	metal ion binding
C	0051213	molecular_function	dioxygenase activity
C	0051536	molecular_function	iron-sulfur cluster binding
C	0051537	molecular_function	2 iron, 2 sulfur cluster binding
D	0006725	biological_process	obsolete cellular aromatic compound metabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
D	0019380	biological_process	3-phenylpropionate catabolic process
D	0019439	biological_process	obsolete aromatic compound catabolic process
D	0051213	molecular_function	dioxygenase activity
E	0005506	molecular_function	iron ion binding
E	0016491	molecular_function	oxidoreductase activity
E	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
E	0019439	biological_process	obsolete aromatic compound catabolic process
E	0044237	biological_process	cellular metabolic process
E	0046872	molecular_function	metal ion binding
E	0051213	molecular_function	dioxygenase activity
E	0051536	molecular_function	iron-sulfur cluster binding
E	0051537	molecular_function	2 iron, 2 sulfur cluster binding
F	0006725	biological_process	obsolete cellular aromatic compound metabolic process
F	0016491	molecular_function	oxidoreductase activity
F	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
F	0019380	biological_process	3-phenylpropionate catabolic process
F	0019439	biological_process	obsolete aromatic compound catabolic process
F	0051213	molecular_function	dioxygenase activity
G	0005506	molecular_function	iron ion binding
G	0016491	molecular_function	oxidoreductase activity
G	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
G	0019439	biological_process	obsolete aromatic compound catabolic process
G	0044237	biological_process	cellular metabolic process
G	0046872	molecular_function	metal ion binding
G	0051213	molecular_function	dioxygenase activity
G	0051536	molecular_function	iron-sulfur cluster binding
G	0051537	molecular_function	2 iron, 2 sulfur cluster binding
H	0006725	biological_process	obsolete cellular aromatic compound metabolic process
H	0016491	molecular_function	oxidoreductase activity
H	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
H	0019380	biological_process	3-phenylpropionate catabolic process
H	0019439	biological_process	obsolete aromatic compound catabolic process
H	0051213	molecular_function	dioxygenase activity
I	0005506	molecular_function	iron ion binding
I	0016491	molecular_function	oxidoreductase activity
I	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
I	0019439	biological_process	obsolete aromatic compound catabolic process
I	0044237	biological_process	cellular metabolic process
I	0046872	molecular_function	metal ion binding
I	0051213	molecular_function	dioxygenase activity
I	0051536	molecular_function	iron-sulfur cluster binding
I	0051537	molecular_function	2 iron, 2 sulfur cluster binding
J	0006725	biological_process	obsolete cellular aromatic compound metabolic process
J	0016491	molecular_function	oxidoreductase activity
J	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
J	0019380	biological_process	3-phenylpropionate catabolic process
J	0019439	biological_process	obsolete aromatic compound catabolic process
J	0051213	molecular_function	dioxygenase activity
K	0005506	molecular_function	iron ion binding
K	0016491	molecular_function	oxidoreductase activity
K	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
K	0019439	biological_process	obsolete aromatic compound catabolic process
K	0044237	biological_process	cellular metabolic process
K	0046872	molecular_function	metal ion binding
K	0051213	molecular_function	dioxygenase activity
K	0051536	molecular_function	iron-sulfur cluster binding
K	0051537	molecular_function	2 iron, 2 sulfur cluster binding
L	0006725	biological_process	obsolete cellular aromatic compound metabolic process
L	0016491	molecular_function	oxidoreductase activity
L	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
L	0019380	biological_process	3-phenylpropionate catabolic process
L	0019439	biological_process	obsolete aromatic compound catabolic process
L	0051213	molecular_function	dioxygenase activity

PDBデータベースに由来する情報

site_id	AC1
残基数	6
詳細	BINDING SITE FOR RESIDUE FES A 900

鎖名	残基
A	CYS100
A	HIS102
A	ARG103
A	CYS120
A	HIS123
A	TRP125

---

site_id	AC2
残基数	5
詳細	BINDING SITE FOR RESIDUE FE2 A 901

鎖名	残基
A	ASP388
A	HOH2109
A	GLN226
A	HIS233
A	HIS239

---

site_id	AC3
残基数	10
詳細	BINDING SITE FOR RESIDUE DC5 A 902

鎖名	残基
A	GLN226
A	ASP230
A	MET231
A	HIS233
A	HIS239
A	SER283
A	GLN322
A	HIS323
A	LEU333
A	PHE384

---

site_id	AC4
残基数	6
詳細	BINDING SITE FOR RESIDUE FES C 900

鎖名	残基
C	CYS100
C	HIS102
C	ARG103
C	CYS120
C	HIS123
C	TRP125

---

site_id	AC5
残基数	5
詳細	BINDING SITE FOR RESIDUE FE2 C 901

鎖名	残基
C	GLN226
C	HIS233
C	HIS239
C	ASP388
C	HOH2073

---

site_id	AC6
残基数	11
詳細	BINDING SITE FOR RESIDUE DC5 C 902

鎖名	残基
C	GLN226
C	ASP230
C	MET231
C	HIS233
C	ALA234
C	HIS239
C	GLN322
C	HIS323
C	LEU333
C	PHE384
C	HOH2073

---

site_id	AC7
残基数	11
詳細	BINDING SITE FOR RESIDUE DC5 E 900

鎖名	残基
E	GLN226
E	ASP230
E	MET231
E	HIS233
E	ALA234
E	HIS239
E	GLN322
E	HIS323
E	LEU333
E	MET336
E	PHE384

---

site_id	AC8
残基数	7
詳細	BINDING SITE FOR RESIDUE FES E 901

鎖名	残基
E	CYS100
E	HIS102
E	ARG103
E	MET105
E	CYS120
E	HIS123
E	TRP125

---

site_id	AC9
残基数	5
詳細	BINDING SITE FOR RESIDUE FE2 E 902

鎖名	残基
E	GLN226
E	HIS233
E	HIS239
E	ASP388
E	HOH2101

---

site_id	BC1
残基数	8
詳細	BINDING SITE FOR RESIDUE FES G 900

鎖名	残基
G	CYS100
G	HIS102
G	ARG103
G	CYS120
G	HIS123
G	TRP125
G	HOH2019
G	HOH2023

---

site_id	BC2
残基数	5
詳細	BINDING SITE FOR RESIDUE FE2 G 901

鎖名	残基
G	GLN226
G	HIS233
G	HIS239
G	ASP388
G	HOH2050

---

site_id	BC3
残基数	7
詳細	BINDING SITE FOR RESIDUE FES I 900

鎖名	残基
I	CYS100
I	HIS102
I	ARG103
I	CYS120
I	HIS123
I	TRP125
I	HOH2025

---

site_id	BC4
残基数	5
詳細	BINDING SITE FOR RESIDUE FE2 I 901

鎖名	残基
I	GLN226
I	HIS233
I	HIS239
I	ASP388
I	HOH2068

---

site_id	BC5
残基数	6
詳細	BINDING SITE FOR RESIDUE FES K 900

鎖名	残基
K	CYS100
K	HIS102
K	ARG103
K	CYS120
K	HIS123
K	TRP125

---

site_id	BC6
残基数	5
詳細	BINDING SITE FOR RESIDUE FE2 K 901

鎖名	残基
K	HIS239
K	ASP388
K	HOH2063
K	GLN226
K	HIS233

---

UniProtにおけるモチーフ・データベースPROSITEからの機能情報

site_id	PS00570
残基数	24
詳細	RING_HYDROXYL_ALPHA Bacterial ring hydroxylating dioxygenases alpha-subunit signature. CrHRGmricrsdaGNakaftCsYH

鎖名	残基	詳細
A	CYS100-HIS123

---

SwissProt/UniProtに記載されている蛋白質分子機能情報

site_id	SWS_FT_FI1
残基数	24
詳細	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00628

鎖名	残基	詳細
A	CYS100
E	HIS102
E	CYS120
E	HIS123
G	CYS100
G	HIS102
G	CYS120
G	HIS123
I	CYS100
I	HIS102
I	CYS120
A	HIS102
I	HIS123
K	CYS100
K	HIS102
K	CYS120
K	HIS123
A	CYS120
A	HIS123
C	CYS100
C	HIS102
C	CYS120
C	HIS123
E	CYS100

---

site_id	SWS_FT_FI2
残基数	12
詳細	BINDING: BINDING => ECO:0000250

鎖名	残基	詳細
A	HIS233
I	HIS239
K	HIS233
K	HIS239
A	HIS239
C	HIS233
C	HIS239
E	HIS233
E	HIS239
G	HIS233
G	HIS239
I	HIS233

---