2XRX

CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE IN COMPLEX WITH BIPHENYL FROM BURKHOLDERIA XENOVORANS LB400

GO（遺伝子オントロジー）由来の情報

鎖名	GO（遺伝子オントロジー）id	名前空間	内容
A	0005506	molecular_function	iron ion binding
A	0016491	molecular_function	oxidoreductase activity
A	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
A	0019439	biological_process	obsolete aromatic compound catabolic process
A	0044237	biological_process	cellular metabolic process
A	0046872	molecular_function	metal ion binding
A	0051213	molecular_function	dioxygenase activity
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
B	0006725	biological_process	obsolete cellular aromatic compound metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
B	0019380	biological_process	3-phenylpropionate catabolic process
B	0019439	biological_process	obsolete aromatic compound catabolic process
B	0051213	molecular_function	dioxygenase activity
C	0005506	molecular_function	iron ion binding
C	0016491	molecular_function	oxidoreductase activity
C	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
C	0019439	biological_process	obsolete aromatic compound catabolic process
C	0044237	biological_process	cellular metabolic process
C	0046872	molecular_function	metal ion binding
C	0051213	molecular_function	dioxygenase activity
C	0051536	molecular_function	iron-sulfur cluster binding
C	0051537	molecular_function	2 iron, 2 sulfur cluster binding
D	0006725	biological_process	obsolete cellular aromatic compound metabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
D	0019380	biological_process	3-phenylpropionate catabolic process
D	0019439	biological_process	obsolete aromatic compound catabolic process
D	0051213	molecular_function	dioxygenase activity
E	0005506	molecular_function	iron ion binding
E	0016491	molecular_function	oxidoreductase activity
E	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
E	0019439	biological_process	obsolete aromatic compound catabolic process
E	0044237	biological_process	cellular metabolic process
E	0046872	molecular_function	metal ion binding
E	0051213	molecular_function	dioxygenase activity
E	0051536	molecular_function	iron-sulfur cluster binding
E	0051537	molecular_function	2 iron, 2 sulfur cluster binding
F	0006725	biological_process	obsolete cellular aromatic compound metabolic process
F	0016491	molecular_function	oxidoreductase activity
F	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
F	0019380	biological_process	3-phenylpropionate catabolic process
F	0019439	biological_process	obsolete aromatic compound catabolic process
F	0051213	molecular_function	dioxygenase activity
G	0005506	molecular_function	iron ion binding
G	0016491	molecular_function	oxidoreductase activity
G	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
G	0019439	biological_process	obsolete aromatic compound catabolic process
G	0044237	biological_process	cellular metabolic process
G	0046872	molecular_function	metal ion binding
G	0051213	molecular_function	dioxygenase activity
G	0051536	molecular_function	iron-sulfur cluster binding
G	0051537	molecular_function	2 iron, 2 sulfur cluster binding
H	0006725	biological_process	obsolete cellular aromatic compound metabolic process
H	0016491	molecular_function	oxidoreductase activity
H	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
H	0019380	biological_process	3-phenylpropionate catabolic process
H	0019439	biological_process	obsolete aromatic compound catabolic process
H	0051213	molecular_function	dioxygenase activity
I	0005506	molecular_function	iron ion binding
I	0016491	molecular_function	oxidoreductase activity
I	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
I	0019439	biological_process	obsolete aromatic compound catabolic process
I	0044237	biological_process	cellular metabolic process
I	0046872	molecular_function	metal ion binding
I	0051213	molecular_function	dioxygenase activity
I	0051536	molecular_function	iron-sulfur cluster binding
I	0051537	molecular_function	2 iron, 2 sulfur cluster binding
J	0006725	biological_process	obsolete cellular aromatic compound metabolic process
J	0016491	molecular_function	oxidoreductase activity
J	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
J	0019380	biological_process	3-phenylpropionate catabolic process
J	0019439	biological_process	obsolete aromatic compound catabolic process
J	0051213	molecular_function	dioxygenase activity
K	0005506	molecular_function	iron ion binding
K	0016491	molecular_function	oxidoreductase activity
K	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
K	0019439	biological_process	obsolete aromatic compound catabolic process
K	0044237	biological_process	cellular metabolic process
K	0046872	molecular_function	metal ion binding
K	0051213	molecular_function	dioxygenase activity
K	0051536	molecular_function	iron-sulfur cluster binding
K	0051537	molecular_function	2 iron, 2 sulfur cluster binding
L	0006725	biological_process	obsolete cellular aromatic compound metabolic process
L	0016491	molecular_function	oxidoreductase activity
L	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
L	0019380	biological_process	3-phenylpropionate catabolic process
L	0019439	biological_process	obsolete aromatic compound catabolic process
L	0051213	molecular_function	dioxygenase activity
M	0005506	molecular_function	iron ion binding
M	0016491	molecular_function	oxidoreductase activity
M	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
M	0019439	biological_process	obsolete aromatic compound catabolic process
M	0044237	biological_process	cellular metabolic process
M	0046872	molecular_function	metal ion binding
M	0051213	molecular_function	dioxygenase activity
M	0051536	molecular_function	iron-sulfur cluster binding
M	0051537	molecular_function	2 iron, 2 sulfur cluster binding
N	0006725	biological_process	obsolete cellular aromatic compound metabolic process
N	0016491	molecular_function	oxidoreductase activity
N	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
N	0019380	biological_process	3-phenylpropionate catabolic process
N	0019439	biological_process	obsolete aromatic compound catabolic process
N	0051213	molecular_function	dioxygenase activity
O	0005506	molecular_function	iron ion binding
O	0016491	molecular_function	oxidoreductase activity
O	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
O	0019439	biological_process	obsolete aromatic compound catabolic process
O	0044237	biological_process	cellular metabolic process
O	0046872	molecular_function	metal ion binding
O	0051213	molecular_function	dioxygenase activity
O	0051536	molecular_function	iron-sulfur cluster binding
O	0051537	molecular_function	2 iron, 2 sulfur cluster binding
P	0006725	biological_process	obsolete cellular aromatic compound metabolic process
P	0016491	molecular_function	oxidoreductase activity
P	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
P	0019380	biological_process	3-phenylpropionate catabolic process
P	0019439	biological_process	obsolete aromatic compound catabolic process
P	0051213	molecular_function	dioxygenase activity
Q	0005506	molecular_function	iron ion binding
Q	0016491	molecular_function	oxidoreductase activity
Q	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
Q	0019439	biological_process	obsolete aromatic compound catabolic process
Q	0044237	biological_process	cellular metabolic process
Q	0046872	molecular_function	metal ion binding
Q	0051213	molecular_function	dioxygenase activity
Q	0051536	molecular_function	iron-sulfur cluster binding
Q	0051537	molecular_function	2 iron, 2 sulfur cluster binding
R	0006725	biological_process	obsolete cellular aromatic compound metabolic process
R	0016491	molecular_function	oxidoreductase activity
R	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
R	0019380	biological_process	3-phenylpropionate catabolic process
R	0019439	biological_process	obsolete aromatic compound catabolic process
R	0051213	molecular_function	dioxygenase activity
S	0005506	molecular_function	iron ion binding
S	0016491	molecular_function	oxidoreductase activity
S	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
S	0019439	biological_process	obsolete aromatic compound catabolic process
S	0044237	biological_process	cellular metabolic process
S	0046872	molecular_function	metal ion binding
S	0051213	molecular_function	dioxygenase activity
S	0051536	molecular_function	iron-sulfur cluster binding
S	0051537	molecular_function	2 iron, 2 sulfur cluster binding
T	0006725	biological_process	obsolete cellular aromatic compound metabolic process
T	0016491	molecular_function	oxidoreductase activity
T	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
T	0019380	biological_process	3-phenylpropionate catabolic process
T	0019439	biological_process	obsolete aromatic compound catabolic process
T	0051213	molecular_function	dioxygenase activity
U	0005506	molecular_function	iron ion binding
U	0016491	molecular_function	oxidoreductase activity
U	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
U	0019439	biological_process	obsolete aromatic compound catabolic process
U	0044237	biological_process	cellular metabolic process
U	0046872	molecular_function	metal ion binding
U	0051213	molecular_function	dioxygenase activity
U	0051536	molecular_function	iron-sulfur cluster binding
U	0051537	molecular_function	2 iron, 2 sulfur cluster binding
V	0006725	biological_process	obsolete cellular aromatic compound metabolic process
V	0016491	molecular_function	oxidoreductase activity
V	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
V	0019380	biological_process	3-phenylpropionate catabolic process
V	0019439	biological_process	obsolete aromatic compound catabolic process
V	0051213	molecular_function	dioxygenase activity
W	0005506	molecular_function	iron ion binding
W	0016491	molecular_function	oxidoreductase activity
W	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
W	0019439	biological_process	obsolete aromatic compound catabolic process
W	0044237	biological_process	cellular metabolic process
W	0046872	molecular_function	metal ion binding
W	0051213	molecular_function	dioxygenase activity
W	0051536	molecular_function	iron-sulfur cluster binding
W	0051537	molecular_function	2 iron, 2 sulfur cluster binding
X	0006725	biological_process	obsolete cellular aromatic compound metabolic process
X	0016491	molecular_function	oxidoreductase activity
X	0018687	molecular_function	biphenyl 2,3-dioxygenase activity
X	0019380	biological_process	3-phenylpropionate catabolic process
X	0019439	biological_process	obsolete aromatic compound catabolic process
X	0051213	molecular_function	dioxygenase activity

PDBデータベースに由来する情報

site_id	AC1
残基数	6
詳細	BINDING SITE FOR RESIDUE FES A 1460

鎖名	残基
A	CYS100
A	HIS102
A	ARG103
A	CYS120
A	HIS123
A	TRP125

---

site_id	AC2
残基数	4
詳細	BINDING SITE FOR RESIDUE FE2 A 1461

鎖名	残基
A	ASP388
A	GLN226
A	HIS233
A	HIS239

---

site_id	AC3
残基数	9
詳細	BINDING SITE FOR RESIDUE BNL A 1462

鎖名	残基
A	GLN226
A	PHE227
A	ASP230
A	HIS233
A	GLY321
A	HIS323
A	LEU333
A	PHE336
A	PHE384

---

site_id	AC4
残基数	6
詳細	BINDING SITE FOR RESIDUE FES C 1460

鎖名	残基
C	CYS100
C	HIS102
C	ARG103
C	CYS120
C	HIS123
C	TRP125

---

site_id	AC5
残基数	5
詳細	BINDING SITE FOR RESIDUE FE2 C 1461

鎖名	残基
C	GLN226
C	HIS233
C	HIS239
C	ASP388
C	HOH2027

---

site_id	AC6
残基数	9
詳細	BINDING SITE FOR RESIDUE BNL C 1462

鎖名	残基
C	GLN226
C	PHE227
C	ASP230
C	MET231
C	HIS233
C	GLY321
C	HIS323
C	LEU333
C	PHE384

---

site_id	AC7
残基数	6
詳細	BINDING SITE FOR RESIDUE FES E 1460

鎖名	残基
E	CYS100
E	HIS102
E	ARG103
E	CYS120
E	HIS123
E	TRP125

---

site_id	AC8
残基数	4
詳細	BINDING SITE FOR RESIDUE FE2 E 1461

鎖名	残基
E	GLN226
E	HIS233
E	HIS239
E	ASP388

---

site_id	AC9
残基数	7
詳細	BINDING SITE FOR RESIDUE BNL E 1462

鎖名	残基
E	GLN226
E	PHE227
E	ASP230
E	HIS233
E	HIS323
E	PHE336
E	PHE384

---

site_id	BC1
残基数	6
詳細	BINDING SITE FOR RESIDUE FES G 1460

鎖名	残基
G	CYS100
G	HIS102
G	ARG103
G	CYS120
G	HIS123
G	TRP125

---

site_id	BC2
残基数	5
詳細	BINDING SITE FOR RESIDUE FE2 G 1461

鎖名	残基
G	GLN226
G	HIS233
G	HIS239
G	ASP388
G	HOH2013

---

site_id	BC3
残基数	9
詳細	BINDING SITE FOR RESIDUE BNL G 1462

鎖名	残基
G	GLN226
G	PHE227
G	ASP230
G	MET231
G	HIS233
G	GLY321
G	HIS323
G	LEU333
G	HOH2013

---

site_id	BC4
残基数	6
詳細	BINDING SITE FOR RESIDUE FES I 1460

鎖名	残基
I	CYS100
I	HIS102
I	ARG103
I	CYS120
I	HIS123
I	TRP125

---

site_id	BC5
残基数	4
詳細	BINDING SITE FOR RESIDUE FE2 I 1461

鎖名	残基
I	GLN226
I	HIS233
I	HIS239
I	ASP388

---

site_id	BC6
残基数	9
詳細	BINDING SITE FOR RESIDUE BNL I 1462

鎖名	残基
I	GLN226
I	PHE227
I	ASP230
I	HIS233
I	ALA234
I	GLY321
I	HIS323
I	LEU333
I	PHE336

---

site_id	BC7
残基数	6
詳細	BINDING SITE FOR RESIDUE FES K 1460

鎖名	残基
K	HIS123
K	TRP125
K	CYS100
K	HIS102
K	ARG103
K	CYS120

---

site_id	BC8
残基数	5
詳細	BINDING SITE FOR RESIDUE FE2 K 1461

鎖名	残基
K	GLN226
K	HIS233
K	HIS239
K	ASP388
K	BNL1462

---

site_id	BC9
残基数	6
詳細	BINDING SITE FOR RESIDUE BNL K 1462

鎖名	残基
K	GLN226
K	ASP230
K	HIS233
K	HIS323
K	PHE384
K	FE21461

---

site_id	CC1
残基数	7
詳細	BINDING SITE FOR RESIDUE FES M 1460

鎖名	残基
M	CYS100
M	HIS102
M	ARG103
M	CYS120
M	TYR122
M	HIS123
M	TRP125

---

site_id	CC2
残基数	5
詳細	BINDING SITE FOR RESIDUE FE2 M 1461

鎖名	残基
M	GLN226
M	HIS233
M	HIS239
M	ASP388
M	HOH2034

---

site_id	CC3
残基数	9
詳細	BINDING SITE FOR RESIDUE BNL M 1462

鎖名	残基
M	GLN226
M	ASP230
M	MET231
M	HIS233
M	GLY321
M	HIS323
M	LEU333
M	PHE336
M	PHE384

---

site_id	CC4
残基数	6
詳細	BINDING SITE FOR RESIDUE FES O 1460

鎖名	残基
O	CYS100
O	HIS102
O	ARG103
O	CYS120
O	HIS123
O	TRP125

---

site_id	CC5
残基数	5
詳細	BINDING SITE FOR RESIDUE FE2 O 1461

鎖名	残基
O	GLN226
O	HIS233
O	HIS239
O	ASP388
O	HOH2053

---

site_id	CC6
残基数	7
詳細	BINDING SITE FOR RESIDUE BNL O 1462

鎖名	残基
O	GLN226
O	ASP230
O	HIS233
O	GLY321
O	HIS323
O	LEU333
O	PHE336

---

site_id	CC7
残基数	6
詳細	BINDING SITE FOR RESIDUE FES Q 1460

鎖名	残基
Q	CYS100
Q	HIS102
Q	ARG103
Q	CYS120
Q	HIS123
Q	TRP125

---

site_id	CC8
残基数	5
詳細	BINDING SITE FOR RESIDUE FE2 Q 1461

鎖名	残基
Q	GLN226
Q	HIS233
Q	HIS239
Q	ASP388
Q	HOH2048

---

site_id	CC9
残基数	6
詳細	BINDING SITE FOR RESIDUE BNL Q 1462

鎖名	残基
Q	GLN226
Q	ASP230
Q	HIS233
Q	HIS323
Q	LEU333
Q	HOH2048

---

site_id	DC1
残基数	7
詳細	BINDING SITE FOR RESIDUE FES S 1460

鎖名	残基
S	CYS100
S	HIS102
S	ARG103
S	MET105
S	CYS120
S	HIS123
S	TRP125

---

site_id	DC2
残基数	5
詳細	BINDING SITE FOR RESIDUE FE2 S 1461

鎖名	残基
S	GLN226
S	HIS233
S	HIS239
S	ASP388
S	BNL1462

---

site_id	DC3
残基数	8
詳細	BINDING SITE FOR RESIDUE BNL S 1462

鎖名	残基
S	GLN226
S	PHE227
S	ASP230
S	HIS233
S	GLY321
S	HIS323
S	PHE336
S	FE21461

---

site_id	DC4
残基数	6
詳細	BINDING SITE FOR RESIDUE FES U 1460

鎖名	残基
U	CYS100
U	HIS102
U	ARG103
U	CYS120
U	HIS123
U	TRP125

---

site_id	DC5
残基数	4
詳細	BINDING SITE FOR RESIDUE FE2 U 1461

鎖名	残基
U	GLN226
U	HIS233
U	HIS239
U	ASP388

---

site_id	DC6
残基数	8
詳細	BINDING SITE FOR RESIDUE BNL U 1462

鎖名	残基
U	GLN226
U	PHE227
U	ASP230
U	HIS233
U	HIS323
U	LEU333
U	PHE336
U	PHE384

---

site_id	DC7
残基数	6
詳細	BINDING SITE FOR RESIDUE FES W 1460

鎖名	残基
W	CYS100
W	HIS102
W	ARG103
W	CYS120
W	HIS123
W	TRP125

---

site_id	DC8
残基数	4
詳細	BINDING SITE FOR RESIDUE FE2 W 1461

鎖名	残基
W	GLN226
W	HIS233
W	HIS239
W	ASP388

---

site_id	DC9
残基数	9
詳細	BINDING SITE FOR RESIDUE BNL W 1462

鎖名	残基
W	GLN226
W	PHE227
W	ASP230
W	HIS233
W	ALA234
W	GLY321
W	HIS323
W	LEU333
W	PHE336

---

UniProtにおけるモチーフ・データベースPROSITEからの機能情報

site_id	PS00570
残基数	24
詳細	RING_HYDROXYL_ALPHA Bacterial ring hydroxylating dioxygenases alpha-subunit signature. CrHRGmricrsdaGNakaftCsYH

鎖名	残基	詳細
A	CYS100-HIS123

---

SwissProt/UniProtに記載されている蛋白質分子機能情報

site_id	SWS_FT_FI1
残基数	48
詳細	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00628

鎖名	残基	詳細
A	CYS100
E	HIS102
E	CYS120
E	HIS123
G	CYS100
G	HIS102
G	CYS120
G	HIS123
I	CYS100
I	HIS102
I	CYS120
A	HIS102
I	HIS123
K	CYS100
K	HIS102
K	CYS120
K	HIS123
M	CYS100
M	HIS102
M	CYS120
M	HIS123
O	CYS100
A	CYS120
O	HIS102
O	CYS120
O	HIS123
Q	CYS100
Q	HIS102
Q	CYS120
Q	HIS123
S	CYS100
S	HIS102
S	CYS120
A	HIS123
S	HIS123
U	CYS100
U	HIS102
U	CYS120
U	HIS123
W	CYS100
W	HIS102
W	CYS120
W	HIS123
C	CYS100
C	HIS102
C	CYS120
C	HIS123
E	CYS100

---

site_id	SWS_FT_FI2
残基数	24
詳細	BINDING: BINDING => ECO:0000250

鎖名	残基	詳細
A	HIS233
I	HIS239
K	HIS233
K	HIS239
M	HIS233
M	HIS239
O	HIS233
O	HIS239
Q	HIS233
Q	HIS239
S	HIS233
A	HIS239
S	HIS239
U	HIS233
U	HIS239
W	HIS233
W	HIS239
C	HIS233
C	HIS239
E	HIS233
E	HIS239
G	HIS233
G	HIS239
I	HIS233

---