Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ZY3 A 2000 |
| Chain | Residue |
| A | GLY72 |
| A | GLN134 |
| A | PHE169 |
| A | ASP289 |
| A | GLY291 |
| A | THR292 |
| A | THR293 |
| A | ASN294 |
| A | ARG296 |
| A | SER386 |
| A | GOL2501 |
| A | GLN73 |
| A | LEU91 |
| A | ASP93 |
| A | GLY95 |
| A | SER96 |
| A | PRO131 |
| A | TYR132 |
| A | THR133 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 2500 |
| Chain | Residue |
| A | LYS70 |
| A | GLY72 |
| A | GLN73 |
| A | GLY74 |
| A | TYR75 |
| A | THR293 |
| A | VAL397 |
| A | HOH2286 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 2501 |
| Chain | Residue |
| A | ASN294 |
| A | ARG368 |
| A | PHE383 |
| A | ALA384 |
| A | ZY32000 |
| A | HOH2006 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 2502 |
| Chain | Residue |
| A | THR80 |
| A | VAL81 |
| A | GLY82 |
| A | SER83 |
| A | LEU145 |
| A | SER147 |
| A | THR155 |
| A | ARG358 |
| A | HOH2287 |
| A | HOH2288 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 2503 |
| Chain | Residue |
| A | GLU138 |
| A | GLU165 |
| A | SER166 |
| A | ASP167 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE90-VAL101 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP93 | |
| A | ASP289 | |
| Chain | Residue | Details |
| A | LYS126 | |
| A | LYS275 | |
| A | LYS279 | |
| A | LYS285 | |
| A | LYS299 | |
| A | LYS300 | |
| A | LYS307 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | GLN153 | |
| A | GLN172 | |
| A | GLN223 | |
| A | GLN354 | |
