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2VV1

hPPARgamma Ligand binding domain in complex with 4-HDHA

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
B0003677molecular_functionDNA binding
B0004879molecular_functionnuclear receptor activity
B0005634cellular_componentnucleus
B0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues10
DetailsBINDING SITE FOR RESIDUE 4HD A 1476
ChainResidue
APHE282
ATYR473
ACYS285
AGLN286
ASER289
AHIS323
ALEU330
AMET364
AHIS449
ALEU469

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE 4HD B 1474
ChainResidue
BCYS285
BARG288
BSER289
BGLU291
BILE326
BLEU330
BVAL339
BSER342
BMET364

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG
ChainResidueDetails
BTHR316
BLEU353

site_idSWS_FT_FI2
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649
ChainResidueDetails
BSER254

218853

数据于2024-04-24公开中

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