2V89
Crystal structure of RAG2-PHD finger in complex with H3K4me3 peptide at 1.1A resolution
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 2488 |
| Chain | Residue |
| A | CYS1419 |
| A | CYS1423 |
| A | HIS1455 |
| A | CYS1458 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 2489 |
| Chain | Residue |
| A | CYS1446 |
| A | HIS1452 |
| A | CYS1478 |
| A | HIS1481 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1488 |
| Chain | Residue |
| B | CYS423 |
| B | HIS455 |
| B | CYS458 |
| B | CYS419 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1489 |
| Chain | Residue |
| B | CYS446 |
| B | HIS452 |
| B | CYS478 |
| B | HIS481 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Citrulline; alternate => ECO:0000269|PubMed:16567635 |
| Chain | Residue | Details |
| D | ARG3002 | |
| E | ARG2002 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by HASPIN => ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088 |
| Chain | Residue | Details |
| D | THR3003 | |
| B | CYS423 | |
| B | CYS446 | |
| B | HIS452 | |
| B | HIS455 | |
| B | CYS458 | |
| B | CYS478 | |
| B | HIS481 | |
| E | THR2003 | |
| A | CYS1446 | |
| A | HIS1452 | |
| A | HIS1455 | |
| A | CYS1458 | |
| A | CYS1478 | |
| A | HIS1481 | |
| B | CYS419 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| D | M3L3004 | |
| E | M3L2004 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: 5-glutamyl serotonin; alternate => ECO:0000269|PubMed:30867594 |
| Chain | Residue | Details |
| D | GLN3005 | |
| E | GLN2005 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by PKC => ECO:0000269|PubMed:20228790 |
| Chain | Residue | Details |
| D | THR3006 | |
| E | THR2006 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Symmetric dimethylarginine; by PRMT5; alternate => ECO:0000250|UniProtKB:P68433 |
| Chain | Residue | Details |
| D | ALA3008 | |
| E | ALA2008 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:11242053, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| D | LYS3009 | |
| E | LYS2009 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5 => ECO:0000269|PubMed:10464286, ECO:0000269|PubMed:11856369, ECO:0000269|PubMed:12560483, ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16457588 |
| Chain | Residue | Details |
| D | ALA3010 | |
| E | ALA2010 |
