2PUH
Crystal Structure of the S112A mutant of a C-C hydrolase, BphD from Burkholderia xenovorans LB400, in complex with its substrate HOPDA
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016823 | molecular_function | hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances |
| A | 0018771 | molecular_function | 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity |
| A | 0018774 | molecular_function | 2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity |
| A | 0019439 | biological_process | obsolete aromatic compound catabolic process |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 3 |
| 詳細 | BINDING SITE FOR RESIDUE NA A 287 |
| 鎖名 | 残基 |
| A | ARG105 |
| A | MLI288 |
| A | HOH392 |
| site_id | AC2 |
| 残基数 | 9 |
| 詳細 | BINDING SITE FOR RESIDUE MLI A 288 |
| 鎖名 | 残基 |
| A | ILE182 |
| A | NA287 |
| A | HOH339 |
| A | THR35 |
| A | ARG65 |
| A | ILE103 |
| A | ASP104 |
| A | ARG105 |
| A | SER180 |
| site_id | AC3 |
| 残基数 | 14 |
| 詳細 | BINDING SITE FOR RESIDUE HPK A 289 |
| 鎖名 | 残基 |
| A | GLY42 |
| A | GLY43 |
| A | ASN51 |
| A | ASN111 |
| A | ALA112 |
| A | MET113 |
| A | ILE153 |
| A | PHE175 |
| A | ARG190 |
| A | LEU213 |
| A | TRP216 |
| A | VAL240 |
| A | HIS265 |
| A | TRP266 |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 1 |
| 詳細 | ACT_SITE: Proton acceptor |
| 鎖名 | 残基 | 詳細 |
| A | HIS265 |
| site_id | SWS_FT_FI2 |
| 残基数 | 6 |
| 詳細 | BINDING: |
| 鎖名 | 残基 | 詳細 |
| A | GLY42 | |
| A | ASN51 | |
| A | ASN111 | |
| A | SER180 | |
| A | ARG190 | |
| A | TRP266 |
| site_id | SWS_FT_FI3 |
| 残基数 | 1 |
| 詳細 | SITE: Transition state stabilizer |
| 鎖名 | 残基 | 詳細 |
| A | ALA112 |
