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2PQ5

Crystal structure of Dual specificity protein phosphatase 13 (DUSP13)

Functional Information from GO Data
ChainGOidnamespacecontents
A0004721molecular_functionphosphoprotein phosphatase activity
A0004722molecular_functionprotein serine/threonine phosphatase activity
A0004725molecular_functionprotein tyrosine phosphatase activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0006470biological_processprotein dephosphorylation
A0007283biological_processspermatogenesis
A0008138molecular_functionprotein tyrosine/serine/threonine phosphatase activity
A0016311biological_processdephosphorylation
A0016787molecular_functionhydrolase activity
A0016791molecular_functionphosphatase activity
A0017018molecular_functionmyosin phosphatase activity
A0033549molecular_functionMAP kinase phosphatase activity
A0043409biological_processnegative regulation of MAPK cascade
A0051321biological_processmeiotic cell cycle
B0004721molecular_functionphosphoprotein phosphatase activity
B0004722molecular_functionprotein serine/threonine phosphatase activity
B0004725molecular_functionprotein tyrosine phosphatase activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0006470biological_processprotein dephosphorylation
B0007283biological_processspermatogenesis
B0008138molecular_functionprotein tyrosine/serine/threonine phosphatase activity
B0016311biological_processdephosphorylation
B0016787molecular_functionhydrolase activity
B0016791molecular_functionphosphatase activity
B0017018molecular_functionmyosin phosphatase activity
B0033549molecular_functionMAP kinase phosphatase activity
B0043409biological_processnegative regulation of MAPK cascade
B0051321biological_processmeiotic cell cycle
C0004721molecular_functionphosphoprotein phosphatase activity
C0004722molecular_functionprotein serine/threonine phosphatase activity
C0004725molecular_functionprotein tyrosine phosphatase activity
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0006470biological_processprotein dephosphorylation
C0007283biological_processspermatogenesis
C0008138molecular_functionprotein tyrosine/serine/threonine phosphatase activity
C0016311biological_processdephosphorylation
C0016787molecular_functionhydrolase activity
C0016791molecular_functionphosphatase activity
C0017018molecular_functionmyosin phosphatase activity
C0033549molecular_functionMAP kinase phosphatase activity
C0043409biological_processnegative regulation of MAPK cascade
C0051321biological_processmeiotic cell cycle
D0004721molecular_functionphosphoprotein phosphatase activity
D0004722molecular_functionprotein serine/threonine phosphatase activity
D0004725molecular_functionprotein tyrosine phosphatase activity
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0006470biological_processprotein dephosphorylation
D0007283biological_processspermatogenesis
D0008138molecular_functionprotein tyrosine/serine/threonine phosphatase activity
D0016311biological_processdephosphorylation
D0016787molecular_functionhydrolase activity
D0016791molecular_functionphosphatase activity
D0017018molecular_functionmyosin phosphatase activity
D0033549molecular_functionMAP kinase phosphatase activity
D0043409biological_processnegative regulation of MAPK cascade
D0051321biological_processmeiotic cell cycle
Functional Information from PROSITE/UniProt
site_idPS00383
Number of Residues11
DetailsTYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCamGvsRSA
ChainResidueDetails
AVAL136-ALA146

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsACT_SITE: Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160
ChainResidueDetails
ACYS138
BCYS138
CCYS138
DCYS138

218853

数据于2024-04-24公开中

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