2PGI

THE CRYSTAL STRUCTURE OF PHOSPHOGLUCOSE ISOMERASE-AN ENZYME WITH AUTOCRINE MOTILITY FACTOR ACTIVITY IN TUMOR CELLS

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Functional Information from GO Data

ChainGOidnamespacecontents
A0005737cellular_componentcytoplasm
A0004347molecular_functionglucose-6-phosphate isomerase activity
A0006094biological_processgluconeogenesis
A0006096biological_processglycolytic process
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Functional Information from PDB Data

site_idNumber of ResiduesDetails
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Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_idNumber of ResiduesDetails
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Functional Information from PROSITE/UniProt

site_idNumber of ResiduesDetails
PS0017418Phosphoglucose isomerase signature 2. [GSA]-x-[LIVMCAYQS]-[LIVMFYWN]-x(4)-[FY]-[DNTH]-Q-x-[GA]-[IV]-[EQST]
ChainResidueDetails
AGLY403-LYS420

PS0076514Phosphoglucose isomerase signature 1. [DENSA]-x-[LIVM]-[GP]-G-R-[FY]-[ST]-[LIVMFSTAP]-x-[GSTA]-[PSTACM]
ChainResidueDetails
AASP197-GLY210

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Functional Information from SwissProt/UniProt

site_idNumber of ResiduesDetails
SWS_FT_FI12By similarity.
ChainResidueDetails
AHIS306
ALYS420

SWS_FT_FI21Proton donor (By similarity).
ChainResidueDetails
AGLU285

CSA16Annotated By Reference To The Literature 1dqr
ChainResidueDetails
AGLY201
AGLU145
AGLU285
ALYS139
ALYS420
AARG202

CSA21Annotated By Reference To The Literature 1dqr
ChainResidueDetails
AHIS306

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Catalytic Information from CSA

site_idNumber of ResiduesDetails
CSA16Annotated By Reference To The Literature 1dqr
ChainResidueDetails
AGLY201
AGLU145
AGLU285
ALYS139
ALYS420
AARG202

CSA21Annotated By Reference To The Literature 1dqr
ChainResidueDetails
AHIS306