2JLN
Structure of Mhp1, a nucleobase-cation-symport-1 family transporter
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0015205 | molecular_function | nucleobase transmembrane transporter activity |
| A | 0016020 | cellular_component | membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0055085 | biological_process | transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1471 |
| Chain | Residue |
| A | ALA38 |
| A | ILE41 |
| A | ALA309 |
| A | SER312 |
| A | THR313 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG A 1472 |
| Chain | Residue |
| A | CYS69 |
| A | TRP220 |
| A | MET260 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE30-GLY50 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL58-PHE78 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU104-LEU124 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU144-ILE164 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000255 |
| Chain | Residue | Details |
| A | MET167-LEU187 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000255 |
| Chain | Residue | Details |
| A | MET207-ILE227 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU258-VAL278 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=8 => ECO:0000255 |
| Chain | Residue | Details |
| A | ALA299-SER321 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=9 => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY339-LEU359 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=10 => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE362-PHE382 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 19 |
| Details | TRANSMEM: Helical; Name=11 => ECO:0000255 |
| Chain | Residue | Details |
| A | ARG405-LEU424 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 17 |
| Details | TRANSMEM: Helical; Name=12 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU428-MET445 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:18927357, ECO:0000305|PubMed:24952894, ECO:0007744|PDB:2JLN, ECO:0007744|PDB:4D1A, ECO:0007744|PDB:4D1B, ECO:0007744|PDB:4D1C, ECO:0007744|PDB:4D1D |
| Chain | Residue | Details |
| A | SER312 | |
| A | THR313 | |
| A | ALA38 | |
| A | ILE41 | |
| A | ALA309 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:24952894, ECO:0007744|PDB:4D1A, ECO:0007744|PDB:4D1B, ECO:0007744|PDB:4D1C, ECO:0007744|PDB:4D1D |
| Chain | Residue | Details |
| A | ASN318 | |
| A | GLN121 | |
| A | GLY219 |
