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2GVL

Crystal Structure of Murine NMPRTase

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0001774biological_processmicroglial cell activation
A0005125molecular_functioncytokine activity
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0007165biological_processsignal transduction
A0007623biological_processcircadian rhythm
A0009435biological_processNAD biosynthetic process
A0010507biological_processnegative regulation of autophagy
A0014916biological_processregulation of lung blood pressure
A0016607cellular_componentnuclear speck
A0016740molecular_functiontransferase activity
A0016757molecular_functionglycosyltransferase activity
A0019363biological_processpyridine nucleotide biosynthetic process
A0030054cellular_componentcell junction
A0032922biological_processcircadian regulation of gene expression
A0042802molecular_functionidentical protein binding
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0047280molecular_functionnicotinamide phosphoribosyltransferase activity
A0048511biological_processrhythmic process
A0048661biological_processpositive regulation of smooth muscle cell proliferation
A0051770biological_processpositive regulation of nitric-oxide synthase biosynthetic process
A1901363molecular_functionheterocyclic compound binding
A2000773biological_processnegative regulation of cellular senescence
B0000166molecular_functionnucleotide binding
B0001774biological_processmicroglial cell activation
B0005125molecular_functioncytokine activity
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0007165biological_processsignal transduction
B0007623biological_processcircadian rhythm
B0009435biological_processNAD biosynthetic process
B0010507biological_processnegative regulation of autophagy
B0014916biological_processregulation of lung blood pressure
B0016607cellular_componentnuclear speck
B0016740molecular_functiontransferase activity
B0016757molecular_functionglycosyltransferase activity
B0019363biological_processpyridine nucleotide biosynthetic process
B0030054cellular_componentcell junction
B0032922biological_processcircadian regulation of gene expression
B0042802molecular_functionidentical protein binding
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0047280molecular_functionnicotinamide phosphoribosyltransferase activity
B0048511biological_processrhythmic process
B0048661biological_processpositive regulation of smooth muscle cell proliferation
B0051770biological_processpositive regulation of nitric-oxide synthase biosynthetic process
B1901363molecular_functionheterocyclic compound binding
B2000773biological_processnegative regulation of cellular senescence
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AARG196
AHIS247
AARG311
BARG311
BARG196
BHIS247

site_idSWS_FT_FI2
Number of Residues8
DetailsBINDING:
ChainResidueDetails
AASP219
AGLY353
BASP219
BGLY353
BGLY384
BARG392
AGLY384
AARG392

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: N-acetylmethionine => ECO:0000250|UniProtKB:P43490
ChainResidueDetails
AMET1
BMET1

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P43490
ChainResidueDetails
ATYR188
BTYR188

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P43490
ChainResidueDetails
ASER472
BSER472

218500

数据于2024-04-17公开中

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