2AOA
Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 12 |
| 詳細 | BINDING SITE FOR RESIDUE S1S A 201 |
| 鎖名 | 残基 |
| A | ARG67 |
| A | LEU111 |
| A | LEU120 |
| B | ARG142 |
| A | ARG86 |
| A | SER88 |
| A | GLU89 |
| A | SER90 |
| A | SER96 |
| A | HIS107 |
| A | PHE108 |
| A | LYS109 |
| site_id | AC2 |
| 残基数 | 17 |
| 詳細 | BINDING SITE FOR RESIDUE S1S B 301 |
| 鎖名 | 残基 |
| A | ASN143 |
| A | S1S401 |
| A | S1S401 |
| A | HOH402 |
| A | HOH406 |
| A | HOH406 |
| A | HOH417 |
| B | ARG86 |
| B | SER96 |
| B | HIS107 |
| B | PHE108 |
| B | LYS109 |
| B | LEU111 |
| B | LEU120 |
| B | TRP121 |
| B | P33501 |
| B | HOH524 |
| site_id | AC3 |
| 残基数 | 16 |
| 詳細 | BINDING SITE FOR RESIDUE S1S A 401 |
| 鎖名 | 残基 |
| A | ASP113 |
| A | LYS117 |
| A | ARG142 |
| A | HOH402 |
| A | HOH404 |
| A | HOH458 |
| B | ASP94 |
| B | LYS109 |
| B | LEU111 |
| B | TRP121 |
| B | VAL122 |
| B | LYS124 |
| B | GLU130 |
| B | S1S301 |
| B | S1S301 |
| B | HOH506 |
| site_id | AC4 |
| 残基数 | 3 |
| 詳細 | BINDING SITE FOR RESIDUE P33 B 501 |
| 鎖名 | 残基 |
| B | ARG112 |
| B | S1S301 |
| B | HOH517 |
SwissProt/UniProtに記載されている蛋白質分子機能情報
