2A4G
Hepatitis C Protease NS3-4A serine protease with Ketoamide Inhibitor SCH225724 Bound
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0019087 | biological_process | transformation of host cell by virus |
| C | 0006508 | biological_process | proteolysis |
| C | 0008236 | molecular_function | serine-type peptidase activity |
| C | 0019087 | biological_process | transformation of host cell by virus |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN A 301 |
| 鎖名 | 残基 |
| A | CYS97 |
| A | CYS99 |
| A | CYS145 |
| A | HOH440 |
| site_id | AC2 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN C 302 |
| 鎖名 | 残基 |
| C | CYS97 |
| C | CYS99 |
| C | CYS145 |
| C | HOH303 |
| site_id | AC3 |
| 残基数 | 13 |
| 詳細 | BINDING SITE FOR RESIDUE UNH A 401 |
| 鎖名 | 残基 |
| A | THR42 |
| A | HIS57 |
| A | ARG123 |
| A | LYS136 |
| A | GLY137 |
| A | SER138 |
| A | SER139 |
| A | PHE154 |
| A | ARG155 |
| A | ALA156 |
| A | ALA157 |
| A | CYS159 |
| A | GLN41 |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 6 |
| 詳細 | ACT_SITE: Charge relay system; for serine protease NS3 activity => ECO:0000255|PROSITE-ProRule:PRU01166 |
| 鎖名 | 残基 | 詳細 |
| A | HIS57 | |
| A | ASP81 | |
| A | SER139 | |
| C | HIS57 | |
| C | ASP81 | |
| C | SER139 |
| site_id | SWS_FT_FI2 |
| 残基数 | 8 |
| 詳細 | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01166 |
| 鎖名 | 残基 | 詳細 |
| A | CYS97 | |
| A | CYS99 | |
| A | CYS145 | |
| A | HIS149 | |
| C | CYS97 | |
| C | CYS99 | |
| C | CYS145 | |
| C | HIS149 |
