1Z8Y

Mapping the E2 Glycoprotein of Alphaviruses

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004252	molecular_function	serine-type endopeptidase activity
A	0019028	cellular_component	viral capsid
A	0055036	cellular_component	virion membrane
B	0004252	molecular_function	serine-type endopeptidase activity
B	0019028	cellular_component	viral capsid
B	0055036	cellular_component	virion membrane
C	0004252	molecular_function	serine-type endopeptidase activity
C	0019028	cellular_component	viral capsid
C	0055036	cellular_component	virion membrane
D	0004252	molecular_function	serine-type endopeptidase activity
D	0019028	cellular_component	viral capsid
D	0055036	cellular_component	virion membrane
E	0004252	molecular_function	serine-type endopeptidase activity
E	0019028	cellular_component	viral capsid
E	0055036	cellular_component	virion membrane
F	0004252	molecular_function	serine-type endopeptidase activity
F	0019028	cellular_component	viral capsid
F	0055036	cellular_component	virion membrane
G	0004252	molecular_function	serine-type endopeptidase activity
G	0019028	cellular_component	viral capsid
G	0055036	cellular_component	virion membrane
H	0004252	molecular_function	serine-type endopeptidase activity
H	0019028	cellular_component	viral capsid
H	0055036	cellular_component	virion membrane
J	0005198	molecular_function	structural molecule activity
J	0019028	cellular_component	viral capsid
L	0005198	molecular_function	structural molecule activity
L	0019028	cellular_component	viral capsid
N	0005198	molecular_function	structural molecule activity
N	0019028	cellular_component	viral capsid
P	0005198	molecular_function	structural molecule activity
P	0019028	cellular_component	viral capsid
Q	0004252	molecular_function	serine-type endopeptidase activity
Q	0006508	biological_process	proteolysis
R	0004252	molecular_function	serine-type endopeptidase activity
R	0006508	biological_process	proteolysis
S	0004252	molecular_function	serine-type endopeptidase activity
S	0006508	biological_process	proteolysis
T	0004252	molecular_function	serine-type endopeptidase activity
T	0006508	biological_process	proteolysis

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	ACT_SITE: Charge relay system => ECO:0000255|PROSITE-ProRule:PRU01027, ECO:0000269|PubMed:1944569

Chain	Residue	Details
Q	HIS141
T	HIS141
T	ASP163
T	SER215
Q	ASP163
Q	SER215
R	HIS141
R	ASP163
R	SER215
S	HIS141
S	ASP163
S	SER215

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site_id	SWS_FT_FI2
Number of Residues	8
Details	SITE: Involved in dimerization of the capsid protein => ECO:0000250|UniProtKB:Q86925

Chain	Residue	Details
Q	TYR189
Q	ASN222
R	TYR189
R	ASN222
S	TYR189
S	ASN222
T	TYR189
T	ASN222

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site_id	SWS_FT_FI3
Number of Residues	4
Details	SITE: Cleavage; by autolysis => ECO:0000250|UniProtKB:P03315

Chain	Residue	Details
Q	TRP264
R	TRP264
S	TRP264
T	TRP264

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