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1YSG

Solution Structure of the Anti-apoptotic Protein Bcl-xL in Complex with "SAR by NMR" Ligands

GO(遺伝子オントロジー)由来の情報
鎖名GO(遺伝子オントロジー)id名前空間内容
A0042981biological_processregulation of apoptotic process
PDBデータベースに由来する情報
site_idAC1
残基数8
詳細BINDING SITE FOR RESIDUE 4FC A 1000
鎖名残基
APHE101
ATYR105
AALA108
APHE109
ALEU134
AGLY142
AARG143
AALA146

site_idAC2
残基数5
詳細BINDING SITE FOR RESIDUE TN1 A 1001
鎖名残基
AGLU100
APHE101
AVAL145
ATYR199
AALA97

UniProtにおけるモチーフ・データベースPROSITEからの機能情報
site_idPS01080
残基数19
詳細BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFsFGG
鎖名残基詳細
ALEU134-GLY152

site_idPS01258
残基数12
詳細BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqenGGWDtFV
鎖名残基詳細
ATRP185-VAL196

site_idPS01259
残基数15
詳細BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VkqaLReAGDEFELR
鎖名残基詳細
AVAL90-ARG104

site_idPS01260
残基数21
詳細BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. SNRELVvDFLSYKLSQKGYsW
鎖名残基詳細
ASER8-TRP28

SwissProt/UniProtに記載されている蛋白質分子機能情報
site_idSWS_FT_FI1
残基数1
詳細SITE: Cleavage; by caspase-1
鎖名残基詳細
ATYR105

site_idSWS_FT_FI2
残基数1
詳細MOD_RES: Phosphoserine; by PLK3 => ECO:0000269|PubMed:21840391
鎖名残基詳細
AALA93

site_idSWS_FT_FI3
残基数1
詳細MOD_RES: Phosphoserine; by CDK1 => ECO:0000269|PubMed:19917720
鎖名残基詳細
AARG106

217705

件を2024-03-27に公開中

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