1YRL

Escherichia coli ketol-acid reductoisomerase

GO（遺伝子オントロジー）由来の情報

鎖名	GO（遺伝子オントロジー）id	名前空間	内容
A	0000287	molecular_function	magnesium ion binding
A	0004455	molecular_function	ketol-acid reductoisomerase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008652	biological_process	amino acid biosynthetic process
A	0008677	molecular_function	2-dehydropantoate 2-reductase activity
A	0009082	biological_process	branched-chain amino acid biosynthetic process
A	0009097	biological_process	isoleucine biosynthetic process
A	0009099	biological_process	valine biosynthetic process
A	0015940	biological_process	pantothenate biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0032991	cellular_component	protein-containing complex
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0050661	molecular_function	NADP binding
B	0000287	molecular_function	magnesium ion binding
B	0004455	molecular_function	ketol-acid reductoisomerase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008652	biological_process	amino acid biosynthetic process
B	0008677	molecular_function	2-dehydropantoate 2-reductase activity
B	0009082	biological_process	branched-chain amino acid biosynthetic process
B	0009097	biological_process	isoleucine biosynthetic process
B	0009099	biological_process	valine biosynthetic process
B	0015940	biological_process	pantothenate biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0032991	cellular_component	protein-containing complex
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	0050661	molecular_function	NADP binding
C	0000287	molecular_function	magnesium ion binding
C	0004455	molecular_function	ketol-acid reductoisomerase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0008652	biological_process	amino acid biosynthetic process
C	0008677	molecular_function	2-dehydropantoate 2-reductase activity
C	0009082	biological_process	branched-chain amino acid biosynthetic process
C	0009097	biological_process	isoleucine biosynthetic process
C	0009099	biological_process	valine biosynthetic process
C	0015940	biological_process	pantothenate biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0032991	cellular_component	protein-containing complex
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
C	0050661	molecular_function	NADP binding
D	0000287	molecular_function	magnesium ion binding
D	0004455	molecular_function	ketol-acid reductoisomerase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0008652	biological_process	amino acid biosynthetic process
D	0008677	molecular_function	2-dehydropantoate 2-reductase activity
D	0009082	biological_process	branched-chain amino acid biosynthetic process
D	0009097	biological_process	isoleucine biosynthetic process
D	0009099	biological_process	valine biosynthetic process
D	0015940	biological_process	pantothenate biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0032991	cellular_component	protein-containing complex
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
D	0050661	molecular_function	NADP binding

PDBデータベースに由来する情報

site_id	AC1
残基数	4
詳細	BINDING SITE FOR RESIDUE SO4 A 4121

鎖名	残基
A	ASN3
A	ASN6
A	HOH4183
A	HOH4282

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site_id	AC2
残基数	2
詳細	BINDING SITE FOR RESIDUE SO4 A 4122

鎖名	残基
A	ARG11
A	GLN12

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site_id	AC3
残基数	2
詳細	BINDING SITE FOR RESIDUE SO4 D 4123

鎖名	残基
D	ASN3
D	ASN6

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site_id	AC4
残基数	3
詳細	BINDING SITE FOR RESIDUE SO4 D 4124

鎖名	残基
D	ARG11
D	GLN12
A	GLN301

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site_id	AC5
残基数	2
詳細	BINDING SITE FOR RESIDUE SO4 C 4125

鎖名	残基
C	ARG11
C	GLN12

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site_id	AC6
残基数	2
詳細	BINDING SITE FOR RESIDUE SO4 B 4126

鎖名	残基
B	ARG11
B	GLN12

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site_id	AC7
残基数	5
詳細	BINDING SITE FOR RESIDUE SO4 A 4127

鎖名	残基
A	ALA71
A	ARG76
A	SER78
A	HOH4156
A	HOH4163

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site_id	AC8
残基数	2
詳細	BINDING SITE FOR RESIDUE SO4 A 4128

鎖名	残基
A	HIS201
A	ARG202

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site_id	AC9
残基数	2
詳細	BINDING SITE FOR RESIDUE SO4 D 4129

鎖名	残基
D	HIS201
D	ARG202

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SwissProt/UniProtに記載されている蛋白質分子機能情報

site_id	SWS_FT_FI1
残基数	4
詳細	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00435

鎖名	残基	詳細
A	GLY133
B	GLY133
C	GLY133
D	GLY133

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site_id	SWS_FT_FI2
残基数	24
詳細	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00435, ECO:0000269|PubMed:23036858

鎖名	残基	詳細
A	SER390
A	LEU394
B	GLY46
B	TRP79
B	LYS109
B	LEU218
B	SER390
B	LEU394
C	GLY46
C	TRP79
C	LYS109
C	LEU218
C	SER390
C	LEU394
D	GLY46
D	TRP79
D	LYS109
D	LEU218
D	SER390
D	LEU394
A	GLY46
A	TRP79
A	LYS109
A	LEU218

---

site_id	SWS_FT_FI3
残基数	4
詳細	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00435, ECO:0000305|PubMed:9015391

鎖名	残基	詳細
A	LYS69
B	LYS69
C	LYS69
D	LYS69

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site_id	SWS_FT_FI4
残基数	4
詳細	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00435, ECO:0000269|PubMed:23036858, ECO:0000305|PubMed:9015391

鎖名	残基	詳細
A	ALA77
B	ALA77
C	ALA77
D	ALA77

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site_id	SWS_FT_FI5
残基数	12
詳細	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00435

鎖名	残基	詳細
B	GLN222
B	ASP415
C	THR159
C	GLN222
C	ASP415
D	THR159
D	GLN222
D	ASP415
A	THR159
A	GLN222
A	ASP415
B	THR159

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