1VPS

POLYOMAVIRUS VP1 PENTAMER COMPLEXED WITH A DISIALYLATED HEXASACCHARIDE

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GO(遺伝子オントロジー)由来の情報

鎖名GO(遺伝子オントロジー)id名前空間内容
A0042025cellular_componenthost cell nucleus
A0039620cellular_componentT=7 icosahedral viral capsid
A0005198molecular_functionstructural molecule activity
A0075513biological_processcaveolin-mediated endocytosis of virus by host cell
A0019062biological_processvirion attachment to host cell
B0042025cellular_componenthost cell nucleus
B0039620cellular_componentT=7 icosahedral viral capsid
B0005198molecular_functionstructural molecule activity
B0075513biological_processcaveolin-mediated endocytosis of virus by host cell
B0019062biological_processvirion attachment to host cell
C0042025cellular_componenthost cell nucleus
C0039620cellular_componentT=7 icosahedral viral capsid
C0005198molecular_functionstructural molecule activity
C0075513biological_processcaveolin-mediated endocytosis of virus by host cell
C0019062biological_processvirion attachment to host cell
D0042025cellular_componenthost cell nucleus
D0039620cellular_componentT=7 icosahedral viral capsid
D0005198molecular_functionstructural molecule activity
D0075513biological_processcaveolin-mediated endocytosis of virus by host cell
D0019062biological_processvirion attachment to host cell
E0042025cellular_componenthost cell nucleus
E0039620cellular_componentT=7 icosahedral viral capsid
E0005198molecular_functionstructural molecule activity
E0075513biological_processcaveolin-mediated endocytosis of virus by host cell
E0019062biological_processvirion attachment to host cell
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PDBデータベースに由来する情報

site_id残基数詳細
AC114BINDING SITE FOR RESIDUE SIA A 1
鎖名残基
AGAL2
ATYR72
AARG77
AGLY78
ATHR291
AASN293
AHIS298
AHOH496
AHOH499
AHOH603
AHOH662
AHOH669
AHOH678
BASP85

AC28BINDING SITE FOR RESIDUE GAL A 2
鎖名残基
ASIA1
ANAG3
AGLY78
AASN93
ATHR94
AHOH660
AHOH662
AHOH663

AC32BINDING SITE FOR RESIDUE NAG A 3
鎖名残基
AGAL2
ASIA4

AC49BINDING SITE FOR RESIDUE SIA A 4
鎖名残基
ANAG3
AASN80
ALEU81
ATHR83
ASER89
ALYS186
AHOH400
AHOH414
AHOH698

AC514BINDING SITE FOR RESIDUE SIA B 1
鎖名残基
BGAL2
BTYR72
BARG77
BGLY78
BTHR291
BASN293
BHIS298
BHOH518
BHOH521
BHOH570
BHOH714
BHOH715
BHOH725
CASP85

AC69BINDING SITE FOR RESIDUE GAL B 2
鎖名残基
BSIA1
BNAG3
BGLY78
BASN93
BTHR94
BHOH659
BHOH684
BHOH713
BHOH714

AC73BINDING SITE FOR RESIDUE NAG B 3
鎖名残基
BGAL2
BSIA4
BHOH713

AC89BINDING SITE FOR RESIDUE SIA B 4
鎖名残基
BNAG3
BASN80
BLEU81
BTHR83
BSER89
BLYS186
BHOH434
BHOH711
BHOH712

AC914BINDING SITE FOR RESIDUE SIA C 1
鎖名残基
CGAL2
CTYR72
CARG77
CGLY78
CTHR291
CASN293
CHIS298
CHOH512
CHOH515
CHOH579
CHOH724
CHOH747
CHOH758
DASP85

BC19BINDING SITE FOR RESIDUE GAL C 2
鎖名残基
CSIA1
CNAG3
CGLY78
CASN93
CTHR94
CHOH598
CHOH626
CHOH724
CHOH726

BC23BINDING SITE FOR RESIDUE NAG C 3
鎖名残基
CGAL2
CSIA4
CHOH598

BC37BINDING SITE FOR RESIDUE SIA C 4
鎖名残基
CNAG3
CASN80
CLEU81
CSER89
CHOH418
CHOH432
CHOH749

BC416BINDING SITE FOR RESIDUE SIA D 1
鎖名残基
DGAL2
DTYR72
DARG77
DGLY78
DTHR291
DASN293
DHIS298
DHOH523
DHOH526
DHOH634
DHOH719
DHOH720
DHOH735
DHOH742
DHOH749
EASP85

BC58BINDING SITE FOR RESIDUE GAL D 2
鎖名残基
DSIA1
DNAG3
DGLY78
DASN93
DTHR94
DHOH717
DHOH720
DHOH726

BC65BINDING SITE FOR RESIDUE NAG D 3
鎖名残基
CTYR294
DGAL2
DSIA4
DHOH734
DHOH740

BC712BINDING SITE FOR RESIDUE SIA D 4
鎖名残基
BASN149
BHOH650
CTYR294
DNAG3
DASN80
DLEU81
DTHR83
DSER89
DLYS186
DHOH628
DHOH718
DHOH728

BC813BINDING SITE FOR RESIDUE SIA E 1
鎖名残基
AASP85
EGAL2
ETYR72
EARG77
EGLY78
ETHR291
EASN293
EHIS298
EHOH528
EHOH531
EHOH595
EHOH668
EHOH672

BC97BINDING SITE FOR RESIDUE GAL E 2
鎖名残基
ESIA1
ENAG3
EGLY78
EASN93
ETHR94
EHOH668
EHOH670

CC13BINDING SITE FOR RESIDUE NAG E 3
鎖名残基
EGAL2
ESIA4
EHOH698

CC27BINDING SITE FOR RESIDUE SIA E 4
鎖名残基
ENAG3
EASN80
ELEU81
ETHR83
ESER89
EHOH435
EHOH665

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「HETATM」原子の座標から抽出されたリガンド結合部位

site_id残基数詳細
SIA_1vps_A_19O-SIALIC ACID binding site
鎖名残基ligand
ATYR72SIA: O-SIALIC ACID
AARG77-GLY78SIA: O-SIALIC ACID
AARG289SIA: O-SIALIC ACID
ATHR291SIA: O-SIALIC ACID
AASN293SIA: O-SIALIC ACID
AVAL296SIA: O-SIALIC ACID
AHIS298SIA: O-SIALIC ACID
BASP85SIA: O-SIALIC ACID

GAL_1vps_A_27BETA-D-GALACTOSE binding site
鎖名残基ligand
AARG77-ASN80GAL: BETA-D-GALACTOSE
AGLY91GAL: BETA-D-GALACTOSE
AASN93-THR94GAL: BETA-D-GALACTOSE

SIA_1vps_A_47O-SIALIC ACID binding site
鎖名残基ligand
AASN80-THR83SIA: O-SIALIC ACID
AGLU87SIA: O-SIALIC ACID
ASER89SIA: O-SIALIC ACID
ALYS186SIA: O-SIALIC ACID

SIA_1vps_E_19O-SIALIC ACID binding site
鎖名残基ligand
AASP85SIA: O-SIALIC ACID
ETYR72SIA: O-SIALIC ACID
EARG77-GLY78SIA: O-SIALIC ACID
EARG289SIA: O-SIALIC ACID
ETHR291SIA: O-SIALIC ACID
EASN293SIA: O-SIALIC ACID
EVAL296SIA: O-SIALIC ACID
EHIS298SIA: O-SIALIC ACID

SIA_1vps_B_19O-SIALIC ACID binding site
鎖名残基ligand
BTYR72SIA: O-SIALIC ACID
BARG77-GLY78SIA: O-SIALIC ACID
BARG289SIA: O-SIALIC ACID
BTHR291SIA: O-SIALIC ACID
BASN293SIA: O-SIALIC ACID
BVAL296SIA: O-SIALIC ACID
BHIS298SIA: O-SIALIC ACID
CASP85SIA: O-SIALIC ACID

GAL_1vps_B_27BETA-D-GALACTOSE binding site
鎖名残基ligand
BARG77-ASN80GAL: BETA-D-GALACTOSE
BGLY91GAL: BETA-D-GALACTOSE
BASN93-THR94GAL: BETA-D-GALACTOSE

SIA_1vps_B_47O-SIALIC ACID binding site
鎖名残基ligand
BASN80-THR83SIA: O-SIALIC ACID
BGLU87SIA: O-SIALIC ACID
BSER89SIA: O-SIALIC ACID
BLYS186SIA: O-SIALIC ACID

SIA_1vps_C_19O-SIALIC ACID binding site
鎖名残基ligand
CTYR72SIA: O-SIALIC ACID
CARG77-GLY78SIA: O-SIALIC ACID
CARG289SIA: O-SIALIC ACID
CTHR291SIA: O-SIALIC ACID
CASN293SIA: O-SIALIC ACID
CVAL296SIA: O-SIALIC ACID
CHIS298SIA: O-SIALIC ACID
DASP85SIA: O-SIALIC ACID

GAL_1vps_C_27BETA-D-GALACTOSE binding site
鎖名残基ligand
CARG77-ASN80GAL: BETA-D-GALACTOSE
CGLY91GAL: BETA-D-GALACTOSE
CASN93-THR94GAL: BETA-D-GALACTOSE

SIA_1vps_C_47O-SIALIC ACID binding site
鎖名残基ligand
CASN80-THR83SIA: O-SIALIC ACID
CGLU87SIA: O-SIALIC ACID
CSER89SIA: O-SIALIC ACID
CLYS186SIA: O-SIALIC ACID

SIA_1vps_D_19O-SIALIC ACID binding site
鎖名残基ligand
DTYR72SIA: O-SIALIC ACID
DARG77-GLY78SIA: O-SIALIC ACID
DARG289SIA: O-SIALIC ACID
DTHR291SIA: O-SIALIC ACID
DASN293SIA: O-SIALIC ACID
DVAL296SIA: O-SIALIC ACID
DHIS298SIA: O-SIALIC ACID
EASP85SIA: O-SIALIC ACID

GAL_1vps_D_27BETA-D-GALACTOSE binding site
鎖名残基ligand
DARG77-ASN80GAL: BETA-D-GALACTOSE
DGLY91GAL: BETA-D-GALACTOSE
DASN93-THR94GAL: BETA-D-GALACTOSE

SIA_1vps_D_47O-SIALIC ACID binding site
鎖名残基ligand
DASN80-THR83SIA: O-SIALIC ACID
DGLU87SIA: O-SIALIC ACID
DSER89SIA: O-SIALIC ACID
DLYS186SIA: O-SIALIC ACID

GAL_1vps_E_27BETA-D-GALACTOSE binding site
鎖名残基ligand
EARG77-ASN80GAL: BETA-D-GALACTOSE
EGLY91GAL: BETA-D-GALACTOSE
EASN93-THR94GAL: BETA-D-GALACTOSE

SIA_1vps_E_47O-SIALIC ACID binding site
鎖名残基ligand
EASN80-THR83SIA: O-SIALIC ACID
EGLU87SIA: O-SIALIC ACID
ESER89SIA: O-SIALIC ACID
ELYS186SIA: O-SIALIC ACID

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UniProtにおけるモチーフ・データベースPROSITEからの機能情報

site_id残基数詳細
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SwissProt/UniProtに記載されている蛋白質分子機能情報

site_id残基数詳細
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CSAにおける酵素触媒機能の情報

site_id残基数詳細