1V8X

Crystal Structure of the Dioxygen-bound Heme Oxygenase from Corynebacterium diphtheriae

GO（遺伝子オントロジー）由来の情報

鎖名	GO（遺伝子オントロジー）id	名前空間	内容
A	0004392	molecular_function	heme oxygenase (decyclizing) activity
A	0006788	biological_process	heme oxidation
A	0006979	biological_process	response to oxidative stress
A	0016491	molecular_function	oxidoreductase activity
A	0020037	molecular_function	heme binding
A	0042167	biological_process	heme catabolic process
A	0046872	molecular_function	metal ion binding
B	0004392	molecular_function	heme oxygenase (decyclizing) activity
B	0006788	biological_process	heme oxidation
B	0006979	biological_process	response to oxidative stress
B	0016491	molecular_function	oxidoreductase activity
B	0020037	molecular_function	heme binding
B	0042167	biological_process	heme catabolic process
B	0046872	molecular_function	metal ion binding
C	0004392	molecular_function	heme oxygenase (decyclizing) activity
C	0006788	biological_process	heme oxidation
C	0006979	biological_process	response to oxidative stress
C	0016491	molecular_function	oxidoreductase activity
C	0020037	molecular_function	heme binding
C	0042167	biological_process	heme catabolic process
C	0046872	molecular_function	metal ion binding

UniProtにおけるモチーフ・データベースPROSITEからの機能情報

site_id	PS00593
残基数	11
詳細	HEME_OXYGENASE Heme oxygenase signature. LVAHHYVRYLG

鎖名	残基	詳細
A	LEU125-GLY135

SwissProt/UniProtに記載されている蛋白質分子機能情報

site_id	SWS_FT_FI1
残基数	3
詳細	BINDING: axial binding residue => ECO:0000250

CSAにおける酵素触媒機能の情報

鎖名	残基	詳細
A	HIS25	metal ligand
A	TYR53	activator, electrostatic stabiliser
A	VAL131	activator
A	ARG132	activator
A	GLY135	steric role
A	ASP136	modifies pKa
A	GLY140	steric role

鎖名	残基	詳細
B	HIS325	metal ligand
B	TYR353	activator, electrostatic stabiliser
B	VAL431	activator
B	ARG432	activator
B	GLY435	steric role
B	ASP436	modifies pKa
B	GLY440	steric role

鎖名	残基	詳細
C	HIS625	metal ligand
C	TYR653	activator, electrostatic stabiliser
C	VAL731	activator
C	ARG732	activator
C	GLY735	steric role
C	ASP736	modifies pKa
C	GLY740	steric role