1SFT
ALANINE RACEMASE
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006522 | biological_process | alanine metabolic process |
| A | 0008784 | molecular_function | alanine racemase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0030632 | biological_process | D-alanine biosynthetic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006522 | biological_process | alanine metabolic process |
| B | 0008784 | molecular_function | alanine racemase activity |
| B | 0009252 | biological_process | peptidoglycan biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0030632 | biological_process | D-alanine biosynthetic process |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 7 |
| 詳細 | BINDING SITE FOR RESIDUE ACT B 400 |
| 鎖名 | 残基 |
| A | LYS39 |
| A | ARG136 |
| A | PLP402 |
| B | TYR265 |
| B | CYS311 |
| B | MET312 |
| B | HOH454 |
| site_id | AC2 |
| 残基数 | 9 |
| 詳細 | BINDING SITE FOR RESIDUE ACT A 401 |
| 鎖名 | 残基 |
| A | CYS311 |
| A | MET312 |
| A | HOH408 |
| A | HOH473 |
| B | LYS39 |
| B | ARG136 |
| B | PLP401 |
| A | TYR265 |
| A | TYR284 |
| site_id | AC3 |
| 残基数 | 14 |
| 詳細 | BINDING SITE FOR RESIDUE PLP A 402 |
| 鎖名 | 残基 |
| A | LYS39 |
| A | TYR43 |
| A | LEU85 |
| A | ARG136 |
| A | HIS166 |
| A | SER204 |
| A | ARG219 |
| A | GLY221 |
| A | ILE222 |
| A | TYR354 |
| A | HOH448 |
| A | HOH463 |
| A | HOH513 |
| B | ACT400 |
| site_id | AC4 |
| 残基数 | 15 |
| 詳細 | BINDING SITE FOR RESIDUE PLP B 401 |
| 鎖名 | 残基 |
| A | ACT401 |
| B | LYS39 |
| B | TYR43 |
| B | LEU85 |
| B | ARG136 |
| B | HIS166 |
| B | ASN203 |
| B | SER204 |
| B | ARG219 |
| B | GLY221 |
| B | ILE222 |
| B | TYR354 |
| B | HOH415 |
| B | HOH461 |
| B | HOH486 |
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
| site_id | PS00395 |
| 残基数 | 11 |
| 詳細 | ALANINE_RACEMASE Alanine racemase pyridoxal-phosphate attachment site. AVvKANAYGHG |
| 鎖名 | 残基 | 詳細 |
| A | ALA36-GLY46 |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 2 |
| 詳細 | ACT_SITE: Proton acceptor; specific for D-alanine => ECO:0000305|PubMed:10502689, ECO:0000305|PubMed:15807525 |
| 鎖名 | 残基 | 詳細 |
| A | LYS39 | |
| B | LYS39 |
| site_id | SWS_FT_FI2 |
| 残基数 | 2 |
| 詳細 | ACT_SITE: Proton acceptor; specific for L-alanine => ECO:0000305|PubMed:10502689, ECO:0000305|PubMed:15807525 |
| 鎖名 | 残基 | 詳細 |
| A | TYR265 | |
| B | TYR265 |
| site_id | SWS_FT_FI3 |
| 残基数 | 4 |
| 詳細 | BINDING: BINDING => ECO:0000269|PubMed:11886871 |
| 鎖名 | 残基 | 詳細 |
| A | ARG136 | |
| A | MET312 | |
| B | ARG136 | |
| B | MET312 |
| site_id | SWS_FT_FI4 |
| 残基数 | 2 |
| 詳細 | MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000269|PubMed:11886871, ECO:0000269|PubMed:15807525, ECO:0000269|PubMed:9063881 |
| 鎖名 | 残基 | 詳細 |
| A | LYS39 | |
| B | LYS39 |
| site_id | SWS_FT_FI5 |
| 残基数 | 2 |
| 詳細 | MOD_RES: N6-carboxylysine => ECO:0000269|PubMed:10079072, ECO:0000269|PubMed:11886871, ECO:0000269|PubMed:12741835, ECO:0000269|PubMed:15807525, ECO:0000269|Ref.10 |
| 鎖名 | 残基 | 詳細 |
| A | LYS129 | |
| B | LYS129 |
CSAにおける酵素触媒機能の情報
| site_id | MCSA1 |
| 残基数 | 7 |
| 詳細 | M-CSA 213 |
| 鎖名 | 残基 | 詳細 |
| A | LYS39 | covalently attached, electron pair acceptor, electron pair donor, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| A | ARG136 | electrostatic stabiliser |
| A | HIS166 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| A | ARG219 | electrostatic stabiliser, hydrogen bond donor |
| A | TYR265 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | CYS311 | electrostatic stabiliser |
| A | ASP313 | electrostatic stabiliser, hydrogen bond acceptor |
| site_id | MCSA2 |
| 残基数 | 7 |
| 詳細 | M-CSA 213 |
| 鎖名 | 残基 | 詳細 |
| B | LYS39 | covalently attached, electron pair acceptor, electron pair donor, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| B | ARG136 | electrostatic stabiliser |
| B | HIS166 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| B | ARG219 | electrostatic stabiliser, hydrogen bond donor |
| B | TYR265 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | CYS311 | electrostatic stabiliser |
| B | ASP313 | electrostatic stabiliser, hydrogen bond acceptor |
