1SEB
COMPLEX OF THE HUMAN MHC CLASS II GLYCOPROTEIN HLA-DR1 AND THE BACTERIAL SUPERANTIGEN SEB
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0006955 | biological_process | immune response |
A | 0016020 | cellular_component | membrane |
A | 0019882 | biological_process | antigen processing and presentation |
A | 0042613 | cellular_component | MHC class II protein complex |
B | 0006955 | biological_process | immune response |
B | 0016020 | cellular_component | membrane |
B | 0019882 | biological_process | antigen processing and presentation |
B | 0042613 | cellular_component | MHC class II protein complex |
D | 0005515 | molecular_function | protein binding |
D | 0005576 | cellular_component | extracellular region |
D | 0035821 | biological_process | modulation of process of another organism |
D | 0046872 | molecular_function | metal ion binding |
D | 0090729 | molecular_function | toxin activity |
E | 0006955 | biological_process | immune response |
E | 0016020 | cellular_component | membrane |
E | 0019882 | biological_process | antigen processing and presentation |
E | 0042613 | cellular_component | MHC class II protein complex |
F | 0006955 | biological_process | immune response |
F | 0016020 | cellular_component | membrane |
F | 0019882 | biological_process | antigen processing and presentation |
F | 0042613 | cellular_component | MHC class II protein complex |
H | 0005515 | molecular_function | protein binding |
H | 0005576 | cellular_component | extracellular region |
H | 0035821 | biological_process | modulation of process of another organism |
H | 0046872 | molecular_function | metal ion binding |
H | 0090729 | molecular_function | toxin activity |
Functional Information from PROSITE/UniProt
site_id | PS00290 |
Number of Residues | 7 |
Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YDCRVEH |
Chain | Residue | Details |
A | TYR161-HIS167 | |
B | TYR171-HIS177 |
site_id | PS00277 |
Number of Residues | 10 |
Details | STAPH_STREP_TOXIN_1 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin signature 1. YGGVTEHngN |
Chain | Residue | Details |
D | TYR115-ASN124 |
site_id | PS00278 |
Number of Residues | 24 |
Details | STAPH_STREP_TOXIN_2 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. KkkVtaqeLDyltRhyLvknkkLY |
Chain | Residue | Details |
D | LYS152-TYR175 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 8 |
Details | BINDING: BINDING => ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819 |
Chain | Residue | Details |
B | ASP57 | |
B | TRP61 | |
B | HIS81 | |
B | ASN82 | |
F | ASP57 | |
F | TRP61 | |
F | HIS81 | |
F | ASN82 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:8145819 |
Chain | Residue | Details |
B | ARG93 | |
F | ARG93 | |
E | GLY49 | |
E | ALA52 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19303388, ECO:0000269|PubMed:24190431 |
Chain | Residue | Details |
B | ASN19 | |
F | ASN19 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819 |
Chain | Residue | Details |
A | SER53 | |
E | SER53 |
site_id | SWS_FT_FI5 |
Number of Residues | 2 |
Details | SITE: Pathogen-derived peptide antigen => ECO:0000269|PubMed:23260142, ECO:0007744|PDB:4GBX |
Chain | Residue | Details |
A | GLU55 | |
E | GLU55 |
site_id | SWS_FT_FI6 |
Number of Residues | 2 |
Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4GBX |
Chain | Residue | Details |
A | ASN62 | |
E | ASN62 |
site_id | SWS_FT_FI7 |
Number of Residues | 2 |
Details | SITE: Pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX |
Chain | Residue | Details |
A | ASN69 | |
E | ASN69 |
site_id | SWS_FT_FI8 |
Number of Residues | 2 |
Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX |
Chain | Residue | Details |
A | ARG76 | |
E | ARG76 |
site_id | SWS_FT_FI9 |
Number of Residues | 4 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400 |
Chain | Residue | Details |
A | ASN78 | |
A | ASN118 | |
E | ASN78 | |
E | ASN118 |