1RKS

E. COLI RIBOKINASE IN COMPLEX WITH D-RIBOSE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004747	molecular_function	ribokinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006014	biological_process	D-ribose metabolic process
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016740	molecular_function	transferase activity
A	0019303	biological_process	D-ribose catabolic process
A	0042803	molecular_function	protein homodimerization activity
A	0046835	biological_process	carbohydrate phosphorylation
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	RB1
Number of Residues	7
Details	RESIDUES MAKING DIRECT HYDROGEN BONDS WITH RIBOSE.

Chain	Residue
A	ASN14
A	ASP16
A	GLY42
A	LYS43
A	ASN46
A	GLU143
A	ASP255

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site_id	RB2
Number of Residues	5
Details	RESIDUES WITHIN VAN DER WAALS DISTANCE OF RIBOSE.

Chain	Residue
A	ILE110
A	ILE112
A	ILE251
A	ALA98
A	ILE100

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Functional Information from PROSITE/UniProt

site_id	PS00584
Number of Residues	14
Details	PFKB_KINASES_2 pfkB family of carbohydrate kinases signature 2. DTiAAGDtfnGALI

Chain	Residue	Details
A	ASP249-ILE262

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_01987, ECO:0000305|PubMed:11786021

Chain	Residue	Details
A	ASP255

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site_id	SWS_FT_FI2
Number of Residues	7
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01987, ECO:0000269|PubMed:10438599, ECO:0000269|PubMed:11786021, ECO:0000269|PubMed:9519409

Chain	Residue	Details
A	GLY42
A	GLU143
A	ASN187
A	THR223
A	ASP255
A	HIS279
A	ASN14

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site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01987, ECO:0000305|PubMed:11786021

Chain	Residue	Details
A	ILE251
A	ALA285
A	ARG288
A	GLY290
A	SER294
A	ASP249

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site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01987, ECO:0000269|PubMed:10438599, ECO:0000269|PubMed:11786021

Chain	Residue	Details
A	GLY254

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	4
Details	M-CSA 663

Chain	Residue	Details
A	ALA252	electrostatic stabiliser, polar interaction
A	ALA253	electrostatic stabiliser, polar interaction
A	GLY254	electrostatic stabiliser, polar interaction
A	ASP255	electrostatic stabiliser, proton acceptor, proton donor

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