Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1QVR

Crystal Structure Analysis of ClpB

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0009408	biological_process	response to heat
A	0016887	molecular_function	ATP hydrolysis activity
A	0034605	biological_process	cellular response to heat
A	0042026	biological_process	protein refolding
A	0042802	molecular_function	identical protein binding
A	0043335	biological_process	protein unfolding
B	0000166	molecular_function	nucleotide binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0009408	biological_process	response to heat
B	0016887	molecular_function	ATP hydrolysis activity
B	0034605	biological_process	cellular response to heat
B	0042026	biological_process	protein refolding
B	0042802	molecular_function	identical protein binding
B	0043335	biological_process	protein unfolding
C	0000166	molecular_function	nucleotide binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0009408	biological_process	response to heat
C	0016887	molecular_function	ATP hydrolysis activity
C	0034605	biological_process	cellular response to heat
C	0042026	biological_process	protein refolding
C	0042802	molecular_function	identical protein binding
C	0043335	biological_process	protein unfolding

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PT B 855

Chain	Residue
B	MET24

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PT B 856

Chain	Residue
B	LYS606
B	MET619

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PT C 855

Chain	Residue
C	LYS606
C	MET619

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PT A 855

Chain	Residue
A	LYS606
A	MET619

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PT B 857

Chain	Residue
C	PRO221
B	MET394
C	ARG180

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PT C 856

Chain	Residue
C	MET624
C	TYR627

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PT A 856

Chain	Residue
A	MET24
A	LYS73

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PT B 858

Chain	Residue
B	MET394
C	ARG180

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PT B 859

Chain	Residue
B	THR625
B	MET628

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PT C 857

Chain	Residue
C	THR625
C	MET628

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PT A 858

Chain	Residue
A	MET234

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PT A 859

Chain	Residue
A	THR625
A	MET628

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PT A 860

Chain	Residue
A	MET394

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PT C 858

Chain	Residue
C	MET234
C	PHE247

site_id	BC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PT C 859

Chain	Residue
C	ARG391
C	MET394

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PT B 861

Chain	Residue
B	MET624
B	TYR627

site_id	BC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PT C 860

Chain	Residue
C	MET24

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PT A 861

Chain	Residue
A	ALA390
A	ARG393
A	MET394
B	GLN184

site_id	CC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PT A 862

Chain	Residue
A	MET624
A	TYR627

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PT C 861

Chain	Residue
A	ARG188
C	MET394

site_id	CC3
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ANP A 901

Chain	Residue
A	VAL172
A	ILE173
A	GLU199
A	PRO200
A	GLY201
A	VAL202
A	GLY203
A	LYS204
A	THR205
A	ALA206
A	ASP270
A	ILE340
A	LEU344
A	ILE382

site_id	CC4
Number of Residues	13
Details	BINDING SITE FOR RESIDUE ANP A 911

Chain	Residue
A	ARG559
A	VAL560
A	VAL561
A	THR597
A	GLY598
A	VAL599
A	GLY600
A	LYS601
A	THR602
A	GLU603
A	ILE765
A	ALA805
A	ARG806

site_id	CC5
Number of Residues	18
Details	BINDING SITE FOR RESIDUE ANP B 902

Chain	Residue
B	PRO171
B	VAL172
B	ILE173
B	GLU199
B	PRO200
B	GLY201
B	VAL202
B	GLY203
B	LYS204
B	THR205
B	ALA206
B	GLU271
B	ILE340
B	LEU344
B	ILE382
C	PRO318
C	GLU321
C	ARG322

site_id	CC6
Number of Residues	15
Details	BINDING SITE FOR RESIDUE ANP B 912

Chain	Residue
B	ARG559
B	VAL560
B	VAL561
B	THR597
B	GLY598
B	VAL599
B	GLY600
B	LYS601
B	THR602
B	GLU603
B	ARG621
B	ILE765
B	GLN769
B	ALA805
B	ARG806

site_id	CC7
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ANP C 903

Chain	Residue
C	PRO171
C	VAL172
C	ILE173
C	PRO200
C	GLY201
C	VAL202
C	GLY203
C	LYS204
C	THR205
C	ALA206
C	GLU209
C	ILE340
C	LEU344
C	ILE382

site_id	CC8
Number of Residues	13
Details	BINDING SITE FOR RESIDUE ANP C 913

Chain	Residue
C	ARG559
C	VAL560
C	VAL561
C	THR597
C	GLY598
C	VAL599
C	GLY600
C	LYS601
C	THR602
C	GLU603
C	ILE765
C	ALA805
C	ARG806

Functional Information from PROSITE/UniProt

site_id	PS00870
Number of Residues	13
Details	CLPAB_1 Chaperonins clpA/B signature 1. DAGNMLKPaLarG

Chain	Residue	Details
A	ASP286-GLY298

site_id	PS00871
Number of Residues	19
Details	CLPAB_2 Chaperonins clpA/B signature 2. RIDmTEYmEKhAvSRLiGA

Chain	Residue	Details
A	ARG621-ALA639

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING:

Chain	Residue	Details
A	GLY198
A	GLY595
B	GLY198
B	GLY595
C	GLY198
C	GLY595

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)