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1QJA

14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 2)

GO(遺伝子オントロジー)由来の情報
鎖名GO(遺伝子オントロジー)id名前空間内容
A0000122biological_processnegative regulation of transcription by RNA polymerase II
A0001525biological_processangiogenesis
A0003016biological_processrespiratory system process
A0003723molecular_functionRNA binding
A0005515molecular_functionprotein binding
A0005615cellular_componentextracellular space
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005925cellular_componentfocal adhesion
A0006468biological_processprotein phosphorylation
A0006605biological_processprotein targeting
A0007165biological_processsignal transduction
A0008039biological_processsynaptic target recognition
A0019901molecular_functionprotein kinase binding
A0019904molecular_functionprotein domain specific binding
A0030324biological_processlung development
A0031625molecular_functionubiquitin protein ligase binding
A0031647biological_processregulation of protein stability
A0031982cellular_componentvesicle
A0035148biological_processtube formation
A0042149biological_processcellular response to glucose starvation
A0042470cellular_componentmelanosome
A0042802molecular_functionidentical protein binding
A0043066biological_processnegative regulation of apoptotic process
A0043067biological_processregulation of programmed cell death
A0044325molecular_functiontransmembrane transporter binding
A0045296molecular_functioncadherin binding
A0045824biological_processnegative regulation of innate immune response
A0050815molecular_functionphosphoserine residue binding
A0051683biological_processestablishment of Golgi localization
A0070062cellular_componentextracellular exosome
A0070371biological_processERK1 and ERK2 cascade
A0070372biological_processregulation of ERK1 and ERK2 cascade
A0072562cellular_componentblood microparticle
A0090128biological_processregulation of synapse maturation
A0090168biological_processGolgi reassembly
A0098686cellular_componenthippocampal mossy fiber to CA3 synapse
A0098978cellular_componentglutamatergic synapse
A0140297molecular_functionDNA-binding transcription factor binding
A0140311molecular_functionprotein sequestering activity
A1900181biological_processnegative regulation of protein localization to nucleus
A1904262biological_processnegative regulation of TORC1 signaling
B0000122biological_processnegative regulation of transcription by RNA polymerase II
B0001525biological_processangiogenesis
B0003016biological_processrespiratory system process
B0003723molecular_functionRNA binding
B0005515molecular_functionprotein binding
B0005615cellular_componentextracellular space
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005925cellular_componentfocal adhesion
B0006468biological_processprotein phosphorylation
B0006605biological_processprotein targeting
B0007165biological_processsignal transduction
B0008039biological_processsynaptic target recognition
B0019901molecular_functionprotein kinase binding
B0019904molecular_functionprotein domain specific binding
B0030324biological_processlung development
B0031625molecular_functionubiquitin protein ligase binding
B0031647biological_processregulation of protein stability
B0031982cellular_componentvesicle
B0035148biological_processtube formation
B0042149biological_processcellular response to glucose starvation
B0042470cellular_componentmelanosome
B0042802molecular_functionidentical protein binding
B0043066biological_processnegative regulation of apoptotic process
B0043067biological_processregulation of programmed cell death
B0044325molecular_functiontransmembrane transporter binding
B0045296molecular_functioncadherin binding
B0045824biological_processnegative regulation of innate immune response
B0050815molecular_functionphosphoserine residue binding
B0051683biological_processestablishment of Golgi localization
B0070062cellular_componentextracellular exosome
B0070371biological_processERK1 and ERK2 cascade
B0070372biological_processregulation of ERK1 and ERK2 cascade
B0072562cellular_componentblood microparticle
B0090128biological_processregulation of synapse maturation
B0090168biological_processGolgi reassembly
B0098686cellular_componenthippocampal mossy fiber to CA3 synapse
B0098978cellular_componentglutamatergic synapse
B0140297molecular_functionDNA-binding transcription factor binding
B0140311molecular_functionprotein sequestering activity
B1900181biological_processnegative regulation of protein localization to nucleus
B1904262biological_processnegative regulation of TORC1 signaling
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
site_idPS00796
残基数11
詳細1433_1 14-3-3 proteins signature 1. RNLLSVAYKNV
鎖名残基詳細
AARG41-VAL51

site_idPS00797
残基数20
詳細1433_2 14-3-3 proteins signature 2. YKDSTLIMQLLRDNLTLWTS
鎖名残基詳細
ATYR211-SER230

SwissProt/UniProtに記載されている蛋白質分子機能情報
site_idSWS_FT_FI1
残基数4
詳細SITE: Interaction with phosphoserine on interacting protein => ECO:0000250|UniProtKB:P63103
鎖名残基詳細
AARG56
AARG127
BARG56
BARG127

site_idSWS_FT_FI2
残基数2
詳細MOD_RES: N-acetylmethionine => ECO:0000269|Ref.8, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712
鎖名残基詳細
AMET1
BMET1

site_idSWS_FT_FI3
残基数4
詳細MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
鎖名残基詳細
ALYS3
ALYS68
BLYS3
BLYS68

site_idSWS_FT_FI4
残基数2
詳細MOD_RES: Phosphoserine; by PKA and PKB/AKT1 => ECO:0000269|PubMed:11956222, ECO:0000269|PubMed:12865427, ECO:0000269|PubMed:15883165, ECO:0000269|PubMed:16376338
鎖名残基詳細
ASER58
BSER58

site_idSWS_FT_FI5
残基数2
詳細MOD_RES: Phosphoserine; by MAPK8 => ECO:0000269|PubMed:15071501, ECO:0000269|PubMed:15696159
鎖名残基詳細
ASER184
BSER184

site_idSWS_FT_FI6
残基数2
詳細MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231
鎖名残基詳細
ASER207
BSER207

site_idSWS_FT_FI7
残基数2
詳細MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P63102
鎖名残基詳細
ASER210
BSER210

site_idSWS_FT_FI8
残基数2
詳細MOD_RES: Phosphothreonine; by CK1 => ECO:0000269|PubMed:31024343, ECO:0000269|PubMed:9360956, ECO:0007744|PubMed:20068231
鎖名残基詳細
ATHR232
BTHR232

218853

件を2024-04-24に公開中

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