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1PDW

Crystal structure of human DJ-1, P 1 21 1 space group

Functional Information from GO Data
ChainGOidnamespacecontents
A0000785cellular_componentchromatin
A0001046molecular_functioncore promoter sequence-specific DNA binding
A0001933biological_processnegative regulation of protein phosphorylation
A0001963biological_processsynaptic transmission, dopaminergic
A0002866biological_processpositive regulation of acute inflammatory response to antigenic stimulus
A0003690molecular_functiondouble-stranded DNA binding
A0003697molecular_functionsingle-stranded DNA binding
A0003713molecular_functiontranscription coactivator activity
A0003723molecular_functionRNA binding
A0003729molecular_functionmRNA binding
A0005102molecular_functionsignaling receptor binding
A0005507molecular_functioncopper ion binding
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005758cellular_componentmitochondrial intermembrane space
A0005759cellular_componentmitochondrial matrix
A0005783cellular_componentendoplasmic reticulum
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0005912cellular_componentadherens junction
A0006281biological_processDNA repair
A0006469biological_processnegative regulation of protein kinase activity
A0006508biological_processproteolysis
A0006517biological_processprotein deglycosylation
A0006914biological_processautophagy
A0006954biological_processinflammatory response
A0006974biological_processDNA damage response
A0006979biological_processresponse to oxidative stress
A0007005biological_processmitochondrion organization
A0007265biological_processRas protein signal transduction
A0007338biological_processsingle fertilization
A0008233molecular_functionpeptidase activity
A0008344biological_processadult locomotory behavior
A0009438biological_processmethylglyoxal metabolic process
A0010273biological_processdetoxification of copper ion
A0010628biological_processpositive regulation of gene expression
A0010629biological_processnegative regulation of gene expression
A0016020cellular_componentmembrane
A0016532molecular_functionsuperoxide dismutase copper chaperone activity
A0016605cellular_componentPML body
A0016684molecular_functionoxidoreductase activity, acting on peroxide as acceptor
A0016787molecular_functionhydrolase activity
A0019249biological_processlactate biosynthetic process
A0019826molecular_functionoxygen sensor activity
A0019899molecular_functionenzyme binding
A0019900molecular_functionkinase binding
A0019955molecular_functioncytokine binding
A0030073biological_processinsulin secretion
A0030424cellular_componentaxon
A0031334biological_processpositive regulation of protein-containing complex assembly
A0031397biological_processnegative regulation of protein ubiquitination
A0032091biological_processnegative regulation of protein binding
A0032148biological_processactivation of protein kinase B activity
A0032435biological_processnegative regulation of proteasomal ubiquitin-dependent protein catabolic process
A0032679biological_processregulation of TRAIL production
A0032757biological_processpositive regulation of interleukin-8 production
A0033138biological_processpositive regulation of peptidyl-serine phosphorylation
A0033234biological_processnegative regulation of protein sumoylation
A0033864biological_processpositive regulation of NAD(P)H oxidase activity
A0034599biological_processcellular response to oxidative stress
A0034614biological_processcellular response to reactive oxygen species
A0036470molecular_functiontyrosine 3-monooxygenase activator activity
A0036471biological_processcellular response to glyoxal
A0036478molecular_functionL-dopa decarboxylase activator activity
A0036524molecular_functionprotein deglycase activity
A0036526biological_processpeptidyl-cysteine deglycation
A0036527biological_processpeptidyl-arginine deglycation
A0036528biological_processpeptidyl-lysine deglycation
A0036529biological_processprotein deglycation, glyoxal removal
A0036530biological_processprotein deglycation, methylglyoxal removal
A0036531biological_processglutathione deglycation
A0042177biological_processnegative regulation of protein catabolic process
A0042542biological_processresponse to hydrogen peroxide
A0042593biological_processglucose homeostasis
A0042743biological_processhydrogen peroxide metabolic process
A0042802molecular_functionidentical protein binding
A0042803molecular_functionprotein homodimerization activity
A0043005cellular_componentneuron projection
A0043523biological_processregulation of neuron apoptotic process
A0043524biological_processnegative regulation of neuron apoptotic process
A0044297cellular_componentcell body
A0044388molecular_functionsmall protein activating enzyme binding
A0044390molecular_functionubiquitin-like protein conjugating enzyme binding
A0044877molecular_functionprotein-containing complex binding
A0045121cellular_componentmembrane raft
A0045202cellular_componentsynapse
A0045296molecular_functioncadherin binding
A0045340molecular_functionmercury ion binding
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0046295biological_processglycolate biosynthetic process
A0046826biological_processnegative regulation of protein export from nucleus
A0048471cellular_componentperinuclear region of cytoplasm
A0050681molecular_functionnuclear androgen receptor binding
A0050727biological_processregulation of inflammatory response
A0050787biological_processdetoxification of mercury ion
A0050821biological_processprotein stabilization
A0051091biological_processpositive regulation of DNA-binding transcription factor activity
A0051444biological_processnegative regulation of ubiquitin-protein transferase activity
A0051583biological_processdopamine uptake involved in synaptic transmission
A0051881biological_processregulation of mitochondrial membrane potential
A0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A0051899biological_processmembrane depolarization
A0051920molecular_functionperoxiredoxin activity
A0060081biological_processmembrane hyperpolarization
A0060765biological_processregulation of androgen receptor signaling pathway
A0061691biological_processdetoxification of hydrogen peroxide
A0061727biological_processmethylglyoxal catabolic process to lactate
A0070062cellular_componentextracellular exosome
A0070301biological_processcellular response to hydrogen peroxide
A0070994biological_processdetection of oxidative stress
A0097110molecular_functionscaffold protein binding
A0098793cellular_componentpresynapse
A0098869biological_processcellular oxidant detoxification
A0106044biological_processguanine deglycation
A0106045biological_processguanine deglycation, methylglyoxal removal
A0106046biological_processguanine deglycation, glyoxal removal
A0110095biological_processcellular detoxification of aldehyde
A0140041biological_processcellular detoxification of methylglyoxal
A0140297molecular_functionDNA-binding transcription factor binding
A1900182biological_processpositive regulation of protein localization to nucleus
A1901671biological_processpositive regulation of superoxide dismutase activity
A1901984biological_processnegative regulation of protein acetylation
A1902176biological_processnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
A1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
A1902236biological_processnegative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
A1902903biological_processregulation of supramolecular fiber organization
A1902958biological_processpositive regulation of mitochondrial electron transport, NADH to ubiquinone
A1903073biological_processnegative regulation of death-inducing signaling complex assembly
A1903094biological_processnegative regulation of protein K48-linked deubiquitination
A1903122biological_processnegative regulation of TRAIL-activated apoptotic signaling pathway
A1903135molecular_functioncupric ion binding
A1903136molecular_functioncuprous ion binding
A1903168biological_processpositive regulation of pyrroline-5-carboxylate reductase activity
A1903178biological_processpositive regulation of tyrosine 3-monooxygenase activity
A1903181biological_processpositive regulation of dopamine biosynthetic process
A1903189biological_processglyoxal metabolic process
A1903190biological_processglyoxal catabolic process
A1903197biological_processpositive regulation of L-dopa biosynthetic process
A1903200biological_processpositive regulation of L-dopa decarboxylase activity
A1903376biological_processregulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
A1903377biological_processnegative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
A1903384biological_processnegative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
A1903427biological_processnegative regulation of reactive oxygen species biosynthetic process
A1903428biological_processpositive regulation of reactive oxygen species biosynthetic process
A1903599biological_processpositive regulation of autophagy of mitochondrion
A1903751biological_processnegative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
A1905259biological_processnegative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
A1990381molecular_functionubiquitin-specific protease binding
A1990422molecular_functionglyoxalase (glycolic acid-forming) activity
A2000157biological_processnegative regulation of ubiquitin-specific protease activity
A2000379biological_processpositive regulation of reactive oxygen species metabolic process
A2000679biological_processpositive regulation of transcription regulatory region DNA binding
A2000825biological_processpositive regulation of androgen receptor activity
A2001237biological_processnegative regulation of extrinsic apoptotic signaling pathway
A2001268biological_processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
B0000785cellular_componentchromatin
B0001046molecular_functioncore promoter sequence-specific DNA binding
B0001933biological_processnegative regulation of protein phosphorylation
B0001963biological_processsynaptic transmission, dopaminergic
B0002866biological_processpositive regulation of acute inflammatory response to antigenic stimulus
B0003690molecular_functiondouble-stranded DNA binding
B0003697molecular_functionsingle-stranded DNA binding
B0003713molecular_functiontranscription coactivator activity
B0003723molecular_functionRNA binding
B0003729molecular_functionmRNA binding
B0005102molecular_functionsignaling receptor binding
B0005507molecular_functioncopper ion binding
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005758cellular_componentmitochondrial intermembrane space
B0005759cellular_componentmitochondrial matrix
B0005783cellular_componentendoplasmic reticulum
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0005912cellular_componentadherens junction
B0006281biological_processDNA repair
B0006469biological_processnegative regulation of protein kinase activity
B0006508biological_processproteolysis
B0006517biological_processprotein deglycosylation
B0006914biological_processautophagy
B0006954biological_processinflammatory response
B0006974biological_processDNA damage response
B0006979biological_processresponse to oxidative stress
B0007005biological_processmitochondrion organization
B0007265biological_processRas protein signal transduction
B0007338biological_processsingle fertilization
B0008233molecular_functionpeptidase activity
B0008344biological_processadult locomotory behavior
B0009438biological_processmethylglyoxal metabolic process
B0010273biological_processdetoxification of copper ion
B0010628biological_processpositive regulation of gene expression
B0010629biological_processnegative regulation of gene expression
B0016020cellular_componentmembrane
B0016532molecular_functionsuperoxide dismutase copper chaperone activity
B0016605cellular_componentPML body
B0016684molecular_functionoxidoreductase activity, acting on peroxide as acceptor
B0016787molecular_functionhydrolase activity
B0019249biological_processlactate biosynthetic process
B0019826molecular_functionoxygen sensor activity
B0019899molecular_functionenzyme binding
B0019900molecular_functionkinase binding
B0019955molecular_functioncytokine binding
B0030073biological_processinsulin secretion
B0030424cellular_componentaxon
B0031334biological_processpositive regulation of protein-containing complex assembly
B0031397biological_processnegative regulation of protein ubiquitination
B0032091biological_processnegative regulation of protein binding
B0032148biological_processactivation of protein kinase B activity
B0032435biological_processnegative regulation of proteasomal ubiquitin-dependent protein catabolic process
B0032679biological_processregulation of TRAIL production
B0032757biological_processpositive regulation of interleukin-8 production
B0033138biological_processpositive regulation of peptidyl-serine phosphorylation
B0033234biological_processnegative regulation of protein sumoylation
B0033864biological_processpositive regulation of NAD(P)H oxidase activity
B0034599biological_processcellular response to oxidative stress
B0034614biological_processcellular response to reactive oxygen species
B0036470molecular_functiontyrosine 3-monooxygenase activator activity
B0036471biological_processcellular response to glyoxal
B0036478molecular_functionL-dopa decarboxylase activator activity
B0036524molecular_functionprotein deglycase activity
B0036526biological_processpeptidyl-cysteine deglycation
B0036527biological_processpeptidyl-arginine deglycation
B0036528biological_processpeptidyl-lysine deglycation
B0036529biological_processprotein deglycation, glyoxal removal
B0036530biological_processprotein deglycation, methylglyoxal removal
B0036531biological_processglutathione deglycation
B0042177biological_processnegative regulation of protein catabolic process
B0042542biological_processresponse to hydrogen peroxide
B0042593biological_processglucose homeostasis
B0042743biological_processhydrogen peroxide metabolic process
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0043005cellular_componentneuron projection
B0043523biological_processregulation of neuron apoptotic process
B0043524biological_processnegative regulation of neuron apoptotic process
B0044297cellular_componentcell body
B0044388molecular_functionsmall protein activating enzyme binding
B0044390molecular_functionubiquitin-like protein conjugating enzyme binding
B0044877molecular_functionprotein-containing complex binding
B0045121cellular_componentmembrane raft
B0045202cellular_componentsynapse
B0045296molecular_functioncadherin binding
B0045340molecular_functionmercury ion binding
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0046295biological_processglycolate biosynthetic process
B0046826biological_processnegative regulation of protein export from nucleus
B0048471cellular_componentperinuclear region of cytoplasm
B0050681molecular_functionnuclear androgen receptor binding
B0050727biological_processregulation of inflammatory response
B0050787biological_processdetoxification of mercury ion
B0050821biological_processprotein stabilization
B0051091biological_processpositive regulation of DNA-binding transcription factor activity
B0051444biological_processnegative regulation of ubiquitin-protein transferase activity
B0051583biological_processdopamine uptake involved in synaptic transmission
B0051881biological_processregulation of mitochondrial membrane potential
B0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
B0051899biological_processmembrane depolarization
B0051920molecular_functionperoxiredoxin activity
B0060081biological_processmembrane hyperpolarization
B0060765biological_processregulation of androgen receptor signaling pathway
B0061691biological_processdetoxification of hydrogen peroxide
B0061727biological_processmethylglyoxal catabolic process to lactate
B0070062cellular_componentextracellular exosome
B0070301biological_processcellular response to hydrogen peroxide
B0070994biological_processdetection of oxidative stress
B0097110molecular_functionscaffold protein binding
B0098793cellular_componentpresynapse
B0098869biological_processcellular oxidant detoxification
B0106044biological_processguanine deglycation
B0106045biological_processguanine deglycation, methylglyoxal removal
B0106046biological_processguanine deglycation, glyoxal removal
B0110095biological_processcellular detoxification of aldehyde
B0140041biological_processcellular detoxification of methylglyoxal
B0140297molecular_functionDNA-binding transcription factor binding
B1900182biological_processpositive regulation of protein localization to nucleus
B1901671biological_processpositive regulation of superoxide dismutase activity
B1901984biological_processnegative regulation of protein acetylation
B1902176biological_processnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
B1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
B1902236biological_processnegative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
B1902903biological_processregulation of supramolecular fiber organization
B1902958biological_processpositive regulation of mitochondrial electron transport, NADH to ubiquinone
B1903073biological_processnegative regulation of death-inducing signaling complex assembly
B1903094biological_processnegative regulation of protein K48-linked deubiquitination
B1903122biological_processnegative regulation of TRAIL-activated apoptotic signaling pathway
B1903135molecular_functioncupric ion binding
B1903136molecular_functioncuprous ion binding
B1903168biological_processpositive regulation of pyrroline-5-carboxylate reductase activity
B1903178biological_processpositive regulation of tyrosine 3-monooxygenase activity
B1903181biological_processpositive regulation of dopamine biosynthetic process
B1903189biological_processglyoxal metabolic process
B1903190biological_processglyoxal catabolic process
B1903197biological_processpositive regulation of L-dopa biosynthetic process
B1903200biological_processpositive regulation of L-dopa decarboxylase activity
B1903376biological_processregulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
B1903377biological_processnegative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
B1903384biological_processnegative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
B1903427biological_processnegative regulation of reactive oxygen species biosynthetic process
B1903428biological_processpositive regulation of reactive oxygen species biosynthetic process
B1903599biological_processpositive regulation of autophagy of mitochondrion
B1903751biological_processnegative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
B1905259biological_processnegative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
B1990381molecular_functionubiquitin-specific protease binding
B1990422molecular_functionglyoxalase (glycolic acid-forming) activity
B2000157biological_processnegative regulation of ubiquitin-specific protease activity
B2000379biological_processpositive regulation of reactive oxygen species metabolic process
B2000679biological_processpositive regulation of transcription regulatory region DNA binding
B2000825biological_processpositive regulation of androgen receptor activity
B2001237biological_processnegative regulation of extrinsic apoptotic signaling pathway
B2001268biological_processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
C0000785cellular_componentchromatin
C0001046molecular_functioncore promoter sequence-specific DNA binding
C0001933biological_processnegative regulation of protein phosphorylation
C0001963biological_processsynaptic transmission, dopaminergic
C0002866biological_processpositive regulation of acute inflammatory response to antigenic stimulus
C0003690molecular_functiondouble-stranded DNA binding
C0003697molecular_functionsingle-stranded DNA binding
C0003713molecular_functiontranscription coactivator activity
C0003723molecular_functionRNA binding
C0003729molecular_functionmRNA binding
C0005102molecular_functionsignaling receptor binding
C0005507molecular_functioncopper ion binding
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005758cellular_componentmitochondrial intermembrane space
C0005759cellular_componentmitochondrial matrix
C0005783cellular_componentendoplasmic reticulum
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0005912cellular_componentadherens junction
C0006281biological_processDNA repair
C0006469biological_processnegative regulation of protein kinase activity
C0006508biological_processproteolysis
C0006517biological_processprotein deglycosylation
C0006914biological_processautophagy
C0006954biological_processinflammatory response
C0006974biological_processDNA damage response
C0006979biological_processresponse to oxidative stress
C0007005biological_processmitochondrion organization
C0007265biological_processRas protein signal transduction
C0007338biological_processsingle fertilization
C0008233molecular_functionpeptidase activity
C0008344biological_processadult locomotory behavior
C0009438biological_processmethylglyoxal metabolic process
C0010273biological_processdetoxification of copper ion
C0010628biological_processpositive regulation of gene expression
C0010629biological_processnegative regulation of gene expression
C0016020cellular_componentmembrane
C0016532molecular_functionsuperoxide dismutase copper chaperone activity
C0016605cellular_componentPML body
C0016684molecular_functionoxidoreductase activity, acting on peroxide as acceptor
C0016787molecular_functionhydrolase activity
C0019249biological_processlactate biosynthetic process
C0019826molecular_functionoxygen sensor activity
C0019899molecular_functionenzyme binding
C0019900molecular_functionkinase binding
C0019955molecular_functioncytokine binding
C0030073biological_processinsulin secretion
C0030424cellular_componentaxon
C0031334biological_processpositive regulation of protein-containing complex assembly
C0031397biological_processnegative regulation of protein ubiquitination
C0032091biological_processnegative regulation of protein binding
C0032148biological_processactivation of protein kinase B activity
C0032435biological_processnegative regulation of proteasomal ubiquitin-dependent protein catabolic process
C0032679biological_processregulation of TRAIL production
C0032757biological_processpositive regulation of interleukin-8 production
C0033138biological_processpositive regulation of peptidyl-serine phosphorylation
C0033234biological_processnegative regulation of protein sumoylation
C0033864biological_processpositive regulation of NAD(P)H oxidase activity
C0034599biological_processcellular response to oxidative stress
C0034614biological_processcellular response to reactive oxygen species
C0036470molecular_functiontyrosine 3-monooxygenase activator activity
C0036471biological_processcellular response to glyoxal
C0036478molecular_functionL-dopa decarboxylase activator activity
C0036524molecular_functionprotein deglycase activity
C0036526biological_processpeptidyl-cysteine deglycation
C0036527biological_processpeptidyl-arginine deglycation
C0036528biological_processpeptidyl-lysine deglycation
C0036529biological_processprotein deglycation, glyoxal removal
C0036530biological_processprotein deglycation, methylglyoxal removal
C0036531biological_processglutathione deglycation
C0042177biological_processnegative regulation of protein catabolic process
C0042542biological_processresponse to hydrogen peroxide
C0042593biological_processglucose homeostasis
C0042743biological_processhydrogen peroxide metabolic process
C0042802molecular_functionidentical protein binding
C0042803molecular_functionprotein homodimerization activity
C0043005cellular_componentneuron projection
C0043523biological_processregulation of neuron apoptotic process
C0043524biological_processnegative regulation of neuron apoptotic process
C0044297cellular_componentcell body
C0044388molecular_functionsmall protein activating enzyme binding
C0044390molecular_functionubiquitin-like protein conjugating enzyme binding
C0044877molecular_functionprotein-containing complex binding
C0045121cellular_componentmembrane raft
C0045202cellular_componentsynapse
C0045296molecular_functioncadherin binding
C0045340molecular_functionmercury ion binding
C0045944biological_processpositive regulation of transcription by RNA polymerase II
C0046295biological_processglycolate biosynthetic process
C0046826biological_processnegative regulation of protein export from nucleus
C0048471cellular_componentperinuclear region of cytoplasm
C0050681molecular_functionnuclear androgen receptor binding
C0050727biological_processregulation of inflammatory response
C0050787biological_processdetoxification of mercury ion
C0050821biological_processprotein stabilization
C0051091biological_processpositive regulation of DNA-binding transcription factor activity
C0051444biological_processnegative regulation of ubiquitin-protein transferase activity
C0051583biological_processdopamine uptake involved in synaptic transmission
C0051881biological_processregulation of mitochondrial membrane potential
C0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
C0051899biological_processmembrane depolarization
C0051920molecular_functionperoxiredoxin activity
C0060081biological_processmembrane hyperpolarization
C0060765biological_processregulation of androgen receptor signaling pathway
C0061691biological_processdetoxification of hydrogen peroxide
C0061727biological_processmethylglyoxal catabolic process to lactate
C0070062cellular_componentextracellular exosome
C0070301biological_processcellular response to hydrogen peroxide
C0070994biological_processdetection of oxidative stress
C0097110molecular_functionscaffold protein binding
C0098793cellular_componentpresynapse
C0098869biological_processcellular oxidant detoxification
C0106044biological_processguanine deglycation
C0106045biological_processguanine deglycation, methylglyoxal removal
C0106046biological_processguanine deglycation, glyoxal removal
C0110095biological_processcellular detoxification of aldehyde
C0140041biological_processcellular detoxification of methylglyoxal
C0140297molecular_functionDNA-binding transcription factor binding
C1900182biological_processpositive regulation of protein localization to nucleus
C1901671biological_processpositive regulation of superoxide dismutase activity
C1901984biological_processnegative regulation of protein acetylation
C1902176biological_processnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
C1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
C1902236biological_processnegative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
C1902903biological_processregulation of supramolecular fiber organization
C1902958biological_processpositive regulation of mitochondrial electron transport, NADH to ubiquinone
C1903073biological_processnegative regulation of death-inducing signaling complex assembly
C1903094biological_processnegative regulation of protein K48-linked deubiquitination
C1903122biological_processnegative regulation of TRAIL-activated apoptotic signaling pathway
C1903135molecular_functioncupric ion binding
C1903136molecular_functioncuprous ion binding
C1903168biological_processpositive regulation of pyrroline-5-carboxylate reductase activity
C1903178biological_processpositive regulation of tyrosine 3-monooxygenase activity
C1903181biological_processpositive regulation of dopamine biosynthetic process
C1903189biological_processglyoxal metabolic process
C1903190biological_processglyoxal catabolic process
C1903197biological_processpositive regulation of L-dopa biosynthetic process
C1903200biological_processpositive regulation of L-dopa decarboxylase activity
C1903376biological_processregulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
C1903377biological_processnegative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
C1903384biological_processnegative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
C1903427biological_processnegative regulation of reactive oxygen species biosynthetic process
C1903428biological_processpositive regulation of reactive oxygen species biosynthetic process
C1903599biological_processpositive regulation of autophagy of mitochondrion
C1903751biological_processnegative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
C1905259biological_processnegative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
C1990381molecular_functionubiquitin-specific protease binding
C1990422molecular_functionglyoxalase (glycolic acid-forming) activity
C2000157biological_processnegative regulation of ubiquitin-specific protease activity
C2000379biological_processpositive regulation of reactive oxygen species metabolic process
C2000679biological_processpositive regulation of transcription regulatory region DNA binding
C2000825biological_processpositive regulation of androgen receptor activity
C2001237biological_processnegative regulation of extrinsic apoptotic signaling pathway
C2001268biological_processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
D0000785cellular_componentchromatin
D0001046molecular_functioncore promoter sequence-specific DNA binding
D0001933biological_processnegative regulation of protein phosphorylation
D0001963biological_processsynaptic transmission, dopaminergic
D0002866biological_processpositive regulation of acute inflammatory response to antigenic stimulus
D0003690molecular_functiondouble-stranded DNA binding
D0003697molecular_functionsingle-stranded DNA binding
D0003713molecular_functiontranscription coactivator activity
D0003723molecular_functionRNA binding
D0003729molecular_functionmRNA binding
D0005102molecular_functionsignaling receptor binding
D0005507molecular_functioncopper ion binding
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005758cellular_componentmitochondrial intermembrane space
D0005759cellular_componentmitochondrial matrix
D0005783cellular_componentendoplasmic reticulum
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0005912cellular_componentadherens junction
D0006281biological_processDNA repair
D0006469biological_processnegative regulation of protein kinase activity
D0006508biological_processproteolysis
D0006517biological_processprotein deglycosylation
D0006914biological_processautophagy
D0006954biological_processinflammatory response
D0006974biological_processDNA damage response
D0006979biological_processresponse to oxidative stress
D0007005biological_processmitochondrion organization
D0007265biological_processRas protein signal transduction
D0007338biological_processsingle fertilization
D0008233molecular_functionpeptidase activity
D0008344biological_processadult locomotory behavior
D0009438biological_processmethylglyoxal metabolic process
D0010273biological_processdetoxification of copper ion
D0010628biological_processpositive regulation of gene expression
D0010629biological_processnegative regulation of gene expression
D0016020cellular_componentmembrane
D0016532molecular_functionsuperoxide dismutase copper chaperone activity
D0016605cellular_componentPML body
D0016684molecular_functionoxidoreductase activity, acting on peroxide as acceptor
D0016787molecular_functionhydrolase activity
D0019249biological_processlactate biosynthetic process
D0019826molecular_functionoxygen sensor activity
D0019899molecular_functionenzyme binding
D0019900molecular_functionkinase binding
D0019955molecular_functioncytokine binding
D0030073biological_processinsulin secretion
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D0033138biological_processpositive regulation of peptidyl-serine phosphorylation
D0033234biological_processnegative regulation of protein sumoylation
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D0034599biological_processcellular response to oxidative stress
D0034614biological_processcellular response to reactive oxygen species
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D0036471biological_processcellular response to glyoxal
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D0036528biological_processpeptidyl-lysine deglycation
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D0036530biological_processprotein deglycation, methylglyoxal removal
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D0042542biological_processresponse to hydrogen peroxide
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D0045340molecular_functionmercury ion binding
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D1903178biological_processpositive regulation of tyrosine 3-monooxygenase activity
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E0032679biological_processregulation of TRAIL production
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E0033138biological_processpositive regulation of peptidyl-serine phosphorylation
E0033234biological_processnegative regulation of protein sumoylation
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E0036528biological_processpeptidyl-lysine deglycation
E0036529biological_processprotein deglycation, glyoxal removal
E0036530biological_processprotein deglycation, methylglyoxal removal
E0036531biological_processglutathione deglycation
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E0046295biological_processglycolate biosynthetic process
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E0051583biological_processdopamine uptake involved in synaptic transmission
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E0070062cellular_componentextracellular exosome
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E0070994biological_processdetection of oxidative stress
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E0098793cellular_componentpresynapse
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E0106044biological_processguanine deglycation
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E0106046biological_processguanine deglycation, glyoxal removal
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E0140041biological_processcellular detoxification of methylglyoxal
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E1902176biological_processnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
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E1902236biological_processnegative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
E1902903biological_processregulation of supramolecular fiber organization
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E1903073biological_processnegative regulation of death-inducing signaling complex assembly
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E1903178biological_processpositive regulation of tyrosine 3-monooxygenase activity
E1903181biological_processpositive regulation of dopamine biosynthetic process
E1903189biological_processglyoxal metabolic process
E1903190biological_processglyoxal catabolic process
E1903197biological_processpositive regulation of L-dopa biosynthetic process
E1903200biological_processpositive regulation of L-dopa decarboxylase activity
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E1903377biological_processnegative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
E1903384biological_processnegative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
E1903427biological_processnegative regulation of reactive oxygen species biosynthetic process
E1903428biological_processpositive regulation of reactive oxygen species biosynthetic process
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E1903751biological_processnegative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
E1905259biological_processnegative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
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E2000679biological_processpositive regulation of transcription regulatory region DNA binding
E2000825biological_processpositive regulation of androgen receptor activity
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F0005654cellular_componentnucleoplasm
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F0033138biological_processpositive regulation of peptidyl-serine phosphorylation
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F0046295biological_processglycolate biosynthetic process
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F0106046biological_processguanine deglycation, glyoxal removal
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F1902176biological_processnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
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F1903094biological_processnegative regulation of protein K48-linked deubiquitination
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F1903135molecular_functioncupric ion binding
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F1903168biological_processpositive regulation of pyrroline-5-carboxylate reductase activity
F1903178biological_processpositive regulation of tyrosine 3-monooxygenase activity
F1903181biological_processpositive regulation of dopamine biosynthetic process
F1903189biological_processglyoxal metabolic process
F1903190biological_processglyoxal catabolic process
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F1903200biological_processpositive regulation of L-dopa decarboxylase activity
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F1903384biological_processnegative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
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F1905259biological_processnegative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
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F2000379biological_processpositive regulation of reactive oxygen species metabolic process
F2000679biological_processpositive regulation of transcription regulatory region DNA binding
F2000825biological_processpositive regulation of androgen receptor activity
F2001237biological_processnegative regulation of extrinsic apoptotic signaling pathway
F2001268biological_processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
G0000785cellular_componentchromatin
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G0005654cellular_componentnucleoplasm
G0005737cellular_componentcytoplasm
G0005739cellular_componentmitochondrion
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G0005759cellular_componentmitochondrial matrix
G0005783cellular_componentendoplasmic reticulum
G0005829cellular_componentcytosol
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G0005912cellular_componentadherens junction
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G0006469biological_processnegative regulation of protein kinase activity
G0006508biological_processproteolysis
G0006517biological_processprotein deglycosylation
G0006914biological_processautophagy
G0006954biological_processinflammatory response
G0006974biological_processDNA damage response
G0006979biological_processresponse to oxidative stress
G0007005biological_processmitochondrion organization
G0007265biological_processRas protein signal transduction
G0007338biological_processsingle fertilization
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G0008344biological_processadult locomotory behavior
G0009438biological_processmethylglyoxal metabolic process
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G0016605cellular_componentPML body
G0016684molecular_functionoxidoreductase activity, acting on peroxide as acceptor
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G0019249biological_processlactate biosynthetic process
G0019826molecular_functionoxygen sensor activity
G0019899molecular_functionenzyme binding
G0019900molecular_functionkinase binding
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G0030073biological_processinsulin secretion
G0030424cellular_componentaxon
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G0031397biological_processnegative regulation of protein ubiquitination
G0032091biological_processnegative regulation of protein binding
G0032148biological_processactivation of protein kinase B activity
G0032435biological_processnegative regulation of proteasomal ubiquitin-dependent protein catabolic process
G0032679biological_processregulation of TRAIL production
G0032757biological_processpositive regulation of interleukin-8 production
G0033138biological_processpositive regulation of peptidyl-serine phosphorylation
G0033234biological_processnegative regulation of protein sumoylation
G0033864biological_processpositive regulation of NAD(P)H oxidase activity
G0034599biological_processcellular response to oxidative stress
G0034614biological_processcellular response to reactive oxygen species
G0036470molecular_functiontyrosine 3-monooxygenase activator activity
G0036471biological_processcellular response to glyoxal
G0036478molecular_functionL-dopa decarboxylase activator activity
G0036524molecular_functionprotein deglycase activity
G0036526biological_processpeptidyl-cysteine deglycation
G0036527biological_processpeptidyl-arginine deglycation
G0036528biological_processpeptidyl-lysine deglycation
G0036529biological_processprotein deglycation, glyoxal removal
G0036530biological_processprotein deglycation, methylglyoxal removal
G0036531biological_processglutathione deglycation
G0042177biological_processnegative regulation of protein catabolic process
G0042542biological_processresponse to hydrogen peroxide
G0042593biological_processglucose homeostasis
G0042743biological_processhydrogen peroxide metabolic process
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G0044297cellular_componentcell body
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G0044390molecular_functionubiquitin-like protein conjugating enzyme binding
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G0045202cellular_componentsynapse
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G0046295biological_processglycolate biosynthetic process
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G0048471cellular_componentperinuclear region of cytoplasm
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G0050787biological_processdetoxification of mercury ion
G0050821biological_processprotein stabilization
G0051091biological_processpositive regulation of DNA-binding transcription factor activity
G0051444biological_processnegative regulation of ubiquitin-protein transferase activity
G0051583biological_processdopamine uptake involved in synaptic transmission
G0051881biological_processregulation of mitochondrial membrane potential
G0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
G0051899biological_processmembrane depolarization
G0051920molecular_functionperoxiredoxin activity
G0060081biological_processmembrane hyperpolarization
G0060765biological_processregulation of androgen receptor signaling pathway
G0061691biological_processdetoxification of hydrogen peroxide
G0061727biological_processmethylglyoxal catabolic process to lactate
G0070062cellular_componentextracellular exosome
G0070301biological_processcellular response to hydrogen peroxide
G0070994biological_processdetection of oxidative stress
G0097110molecular_functionscaffold protein binding
G0098793cellular_componentpresynapse
G0098869biological_processcellular oxidant detoxification
G0106044biological_processguanine deglycation
G0106045biological_processguanine deglycation, methylglyoxal removal
G0106046biological_processguanine deglycation, glyoxal removal
G0110095biological_processcellular detoxification of aldehyde
G0140041biological_processcellular detoxification of methylglyoxal
G0140297molecular_functionDNA-binding transcription factor binding
G1900182biological_processpositive regulation of protein localization to nucleus
G1901671biological_processpositive regulation of superoxide dismutase activity
G1901984biological_processnegative regulation of protein acetylation
G1902176biological_processnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
G1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
G1902236biological_processnegative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
G1902903biological_processregulation of supramolecular fiber organization
G1902958biological_processpositive regulation of mitochondrial electron transport, NADH to ubiquinone
G1903073biological_processnegative regulation of death-inducing signaling complex assembly
G1903094biological_processnegative regulation of protein K48-linked deubiquitination
G1903122biological_processnegative regulation of TRAIL-activated apoptotic signaling pathway
G1903135molecular_functioncupric ion binding
G1903136molecular_functioncuprous ion binding
G1903168biological_processpositive regulation of pyrroline-5-carboxylate reductase activity
G1903178biological_processpositive regulation of tyrosine 3-monooxygenase activity
G1903181biological_processpositive regulation of dopamine biosynthetic process
G1903189biological_processglyoxal metabolic process
G1903190biological_processglyoxal catabolic process
G1903197biological_processpositive regulation of L-dopa biosynthetic process
G1903200biological_processpositive regulation of L-dopa decarboxylase activity
G1903376biological_processregulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
G1903377biological_processnegative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
G1903384biological_processnegative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
G1903427biological_processnegative regulation of reactive oxygen species biosynthetic process
G1903428biological_processpositive regulation of reactive oxygen species biosynthetic process
G1903599biological_processpositive regulation of autophagy of mitochondrion
G1903751biological_processnegative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
G1905259biological_processnegative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
G1990381molecular_functionubiquitin-specific protease binding
G1990422molecular_functionglyoxalase (glycolic acid-forming) activity
G2000157biological_processnegative regulation of ubiquitin-specific protease activity
G2000379biological_processpositive regulation of reactive oxygen species metabolic process
G2000679biological_processpositive regulation of transcription regulatory region DNA binding
G2000825biological_processpositive regulation of androgen receptor activity
G2001237biological_processnegative regulation of extrinsic apoptotic signaling pathway
G2001268biological_processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
H0000785cellular_componentchromatin
H0001046molecular_functioncore promoter sequence-specific DNA binding
H0001933biological_processnegative regulation of protein phosphorylation
H0001963biological_processsynaptic transmission, dopaminergic
H0002866biological_processpositive regulation of acute inflammatory response to antigenic stimulus
H0003690molecular_functiondouble-stranded DNA binding
H0003697molecular_functionsingle-stranded DNA binding
H0003713molecular_functiontranscription coactivator activity
H0003723molecular_functionRNA binding
H0003729molecular_functionmRNA binding
H0005102molecular_functionsignaling receptor binding
H0005507molecular_functioncopper ion binding
H0005515molecular_functionprotein binding
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0005737cellular_componentcytoplasm
H0005739cellular_componentmitochondrion
H0005758cellular_componentmitochondrial intermembrane space
H0005759cellular_componentmitochondrial matrix
H0005783cellular_componentendoplasmic reticulum
H0005829cellular_componentcytosol
H0005886cellular_componentplasma membrane
H0005912cellular_componentadherens junction
H0006281biological_processDNA repair
H0006469biological_processnegative regulation of protein kinase activity
H0006508biological_processproteolysis
H0006517biological_processprotein deglycosylation
H0006914biological_processautophagy
H0006954biological_processinflammatory response
H0006974biological_processDNA damage response
H0006979biological_processresponse to oxidative stress
H0007005biological_processmitochondrion organization
H0007265biological_processRas protein signal transduction
H0007338biological_processsingle fertilization
H0008233molecular_functionpeptidase activity
H0008344biological_processadult locomotory behavior
H0009438biological_processmethylglyoxal metabolic process
H0010273biological_processdetoxification of copper ion
H0010628biological_processpositive regulation of gene expression
H0010629biological_processnegative regulation of gene expression
H0016020cellular_componentmembrane
H0016532molecular_functionsuperoxide dismutase copper chaperone activity
H0016605cellular_componentPML body
H0016684molecular_functionoxidoreductase activity, acting on peroxide as acceptor
H0016787molecular_functionhydrolase activity
H0019249biological_processlactate biosynthetic process
H0019826molecular_functionoxygen sensor activity
H0019899molecular_functionenzyme binding
H0019900molecular_functionkinase binding
H0019955molecular_functioncytokine binding
H0030073biological_processinsulin secretion
H0030424cellular_componentaxon
H0031334biological_processpositive regulation of protein-containing complex assembly
H0031397biological_processnegative regulation of protein ubiquitination
H0032091biological_processnegative regulation of protein binding
H0032148biological_processactivation of protein kinase B activity
H0032435biological_processnegative regulation of proteasomal ubiquitin-dependent protein catabolic process
H0032679biological_processregulation of TRAIL production
H0032757biological_processpositive regulation of interleukin-8 production
H0033138biological_processpositive regulation of peptidyl-serine phosphorylation
H0033234biological_processnegative regulation of protein sumoylation
H0033864biological_processpositive regulation of NAD(P)H oxidase activity
H0034599biological_processcellular response to oxidative stress
H0034614biological_processcellular response to reactive oxygen species
H0036470molecular_functiontyrosine 3-monooxygenase activator activity
H0036471biological_processcellular response to glyoxal
H0036478molecular_functionL-dopa decarboxylase activator activity
H0036524molecular_functionprotein deglycase activity
H0036526biological_processpeptidyl-cysteine deglycation
H0036527biological_processpeptidyl-arginine deglycation
H0036528biological_processpeptidyl-lysine deglycation
H0036529biological_processprotein deglycation, glyoxal removal
H0036530biological_processprotein deglycation, methylglyoxal removal
H0036531biological_processglutathione deglycation
H0042177biological_processnegative regulation of protein catabolic process
H0042542biological_processresponse to hydrogen peroxide
H0042593biological_processglucose homeostasis
H0042743biological_processhydrogen peroxide metabolic process
H0042802molecular_functionidentical protein binding
H0042803molecular_functionprotein homodimerization activity
H0043005cellular_componentneuron projection
H0043523biological_processregulation of neuron apoptotic process
H0043524biological_processnegative regulation of neuron apoptotic process
H0044297cellular_componentcell body
H0044388molecular_functionsmall protein activating enzyme binding
H0044390molecular_functionubiquitin-like protein conjugating enzyme binding
H0044877molecular_functionprotein-containing complex binding
H0045121cellular_componentmembrane raft
H0045202cellular_componentsynapse
H0045296molecular_functioncadherin binding
H0045340molecular_functionmercury ion binding
H0045944biological_processpositive regulation of transcription by RNA polymerase II
H0046295biological_processglycolate biosynthetic process
H0046826biological_processnegative regulation of protein export from nucleus
H0048471cellular_componentperinuclear region of cytoplasm
H0050681molecular_functionnuclear androgen receptor binding
H0050727biological_processregulation of inflammatory response
H0050787biological_processdetoxification of mercury ion
H0050821biological_processprotein stabilization
H0051091biological_processpositive regulation of DNA-binding transcription factor activity
H0051444biological_processnegative regulation of ubiquitin-protein transferase activity
H0051583biological_processdopamine uptake involved in synaptic transmission
H0051881biological_processregulation of mitochondrial membrane potential
H0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
H0051899biological_processmembrane depolarization
H0051920molecular_functionperoxiredoxin activity
H0060081biological_processmembrane hyperpolarization
H0060765biological_processregulation of androgen receptor signaling pathway
H0061691biological_processdetoxification of hydrogen peroxide
H0061727biological_processmethylglyoxal catabolic process to lactate
H0070062cellular_componentextracellular exosome
H0070301biological_processcellular response to hydrogen peroxide
H0070994biological_processdetection of oxidative stress
H0097110molecular_functionscaffold protein binding
H0098793cellular_componentpresynapse
H0098869biological_processcellular oxidant detoxification
H0106044biological_processguanine deglycation
H0106045biological_processguanine deglycation, methylglyoxal removal
H0106046biological_processguanine deglycation, glyoxal removal
H0110095biological_processcellular detoxification of aldehyde
H0140041biological_processcellular detoxification of methylglyoxal
H0140297molecular_functionDNA-binding transcription factor binding
H1900182biological_processpositive regulation of protein localization to nucleus
H1901671biological_processpositive regulation of superoxide dismutase activity
H1901984biological_processnegative regulation of protein acetylation
H1902176biological_processnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
H1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
H1902236biological_processnegative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
H1902903biological_processregulation of supramolecular fiber organization
H1902958biological_processpositive regulation of mitochondrial electron transport, NADH to ubiquinone
H1903073biological_processnegative regulation of death-inducing signaling complex assembly
H1903094biological_processnegative regulation of protein K48-linked deubiquitination
H1903122biological_processnegative regulation of TRAIL-activated apoptotic signaling pathway
H1903135molecular_functioncupric ion binding
H1903136molecular_functioncuprous ion binding
H1903168biological_processpositive regulation of pyrroline-5-carboxylate reductase activity
H1903178biological_processpositive regulation of tyrosine 3-monooxygenase activity
H1903181biological_processpositive regulation of dopamine biosynthetic process
H1903189biological_processglyoxal metabolic process
H1903190biological_processglyoxal catabolic process
H1903197biological_processpositive regulation of L-dopa biosynthetic process
H1903200biological_processpositive regulation of L-dopa decarboxylase activity
H1903376biological_processregulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
H1903377biological_processnegative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
H1903384biological_processnegative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
H1903427biological_processnegative regulation of reactive oxygen species biosynthetic process
H1903428biological_processpositive regulation of reactive oxygen species biosynthetic process
H1903599biological_processpositive regulation of autophagy of mitochondrion
H1903751biological_processnegative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
H1905259biological_processnegative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
H1990381molecular_functionubiquitin-specific protease binding
H1990422molecular_functionglyoxalase (glycolic acid-forming) activity
H2000157biological_processnegative regulation of ubiquitin-specific protease activity
H2000379biological_processpositive regulation of reactive oxygen species metabolic process
H2000679biological_processpositive regulation of transcription regulatory region DNA binding
H2000825biological_processpositive regulation of androgen receptor activity
H2001237biological_processnegative regulation of extrinsic apoptotic signaling pathway
H2001268biological_processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsACT_SITE: Nucleophile => ECO:0000305|PubMed:20304780, ECO:0000305|PubMed:25416785
ChainResidueDetails
ACYS106
BCYS306
CCYS1106
DCYS1306
ECYS2106
FCYS2306
GCYS3106
HCYS3306

site_idSWS_FT_FI2
Number of Residues8
DetailsACT_SITE: ACT_SITE => ECO:0000305|PubMed:20304780
ChainResidueDetails
AHIS126
BHIS326
CHIS1126
DHIS1326
EHIS2126
FHIS2326
GHIS3126
HHIS3326

site_idSWS_FT_FI3
Number of Residues8
DetailsSITE: Cleavage; by CASP6 => ECO:0000250|UniProtKB:Q99LX0
ChainResidueDetails
AASP149
BASP349
CASP1149
DASP1349
EASP2149
FASP2349
GASP3149
HASP3349

site_idSWS_FT_FI4
Number of Residues8
DetailsMOD_RES: N-acetylalanine => ECO:0007744|PubMed:25944712
ChainResidueDetails
AALA2
BALA202
CALA1002
DALA1202
EALA2002
FALA2202
GALA3002
HALA3202

site_idSWS_FT_FI5
Number of Residues8
DetailsMOD_RES: Phosphotyrosine => ECO:0007744|PubMed:15592455
ChainResidueDetails
ATYR67
BTYR267
CTYR1067
DTYR1267
ETYR2067
FTYR2267
GTYR3067
HTYR3267

site_idSWS_FT_FI6
Number of Residues8
DetailsMOD_RES: Cysteine sulfinic acid (-SO2H); alternate => ECO:0000269|PubMed:12939276
ChainResidueDetails
ACYS106
BCYS306
CCYS1106
DCYS1306
ECYS2106
FCYS2306
GCYS3106
HCYS3306

site_idSWS_FT_FI7
Number of Residues8
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q99LX0
ChainResidueDetails
ALYS148
BLYS348
CLYS1148
DLYS1348
ELYS2148
FLYS2348
GLYS3148
HLYS3348

site_idSWS_FT_FI8
Number of Residues8
DetailsMOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q99LX0
ChainResidueDetails
ALYS182
BLYS382
CLYS1182
DLYS1382
ELYS2182
FLYS2382
GLYS3182
HLYS3382

site_idSWS_FT_FI9
Number of Residues16
DetailsLIPID: S-palmitoyl cysteine => ECO:0000269|PubMed:23847046
ChainResidueDetails
ACYS46
ECYS2053
FCYS2246
FCYS2253
GCYS3046
GCYS3053
HCYS3246
HCYS3253
ACYS53
BCYS246
BCYS253
CCYS1046
CCYS1053
DCYS1246
DCYS1253
ECYS2046

site_idSWS_FT_FI10
Number of Residues8
DetailsLIPID: S-palmitoyl cysteine; alternate => ECO:0000269|PubMed:23847046
ChainResidueDetails
ACYS106
BCYS306
CCYS1106
DCYS1306
ECYS2106
FCYS2306
GCYS3106
HCYS3306

site_idSWS_FT_FI11
Number of Residues16
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:15976810
ChainResidueDetails
ALYS130
FLYS2330
GLYS3130
HLYS3330
BLYS330
CLYS1130
DLYS1330
ELYS2130

218853

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