1NI2

Structure of the active FERM domain of Ezrin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003779	molecular_function	actin binding
A	0005856	cellular_component	cytoskeleton
A	0008092	molecular_function	cytoskeletal protein binding
B	0003779	molecular_function	actin binding
B	0005856	cellular_component	cytoskeleton
B	0008092	molecular_function	cytoskeletal protein binding

Functional Information from PROSITE/UniProt

site_id	PS00660
Number of Residues	31
Details	FERM_1 FERM domain signature 1. WLkldKkVsaQe.Vrkenplq.FkfrakFYpeD

Chain	Residue	Details
A	TRP58-ASP88

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site_id	PS00661
Number of Residues	30
Details	FERM_2 FERM domain signature 2. HaehrgmlkdNAmleYLki.AqdLemYGiNY

Chain	Residue	Details
A	HIS176-TYR205

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LEU61
B	LEU61

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphotyrosine; by PDGFR => ECO:0000269|PubMed:1382070, ECO:0000269|PubMed:18046454

Chain	Residue	Details
A	LEU147
B	LEU147

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